Sig Brokerage, LP Biotechnology

Sig Brokerage, LP

  • $3.47 Trillion
  • Q3 2025

Stock List

Stock Option Type Value Options Held Last Trade Trade History
REGN
Regeneron Pharmaceuticals, Inc.
CALL
$7.87 Billion
14K
Q4 2024
New holding
UTHR
United Therapeutics Corp
PUT
$7.13 Billion
17K
Q3 2025
New holding
VRTX
Vertex Pharmaceuticals Inc
PUT
$5.91 Billion
15.1K
Q3 2025
Reduced 18.96%
MRUS
Merus N.V.
CALL
$5.65 Billion
60K N/A
KRYS
Krystal Biotech, Inc.
PUT
$4.73 Billion
26.8K
Q3 2025
New holding
QURE
Uni Qure N.V.
CALL
$2.98 Billion
51K
Q3 2025
New holding
MRNA
Moderna, Inc.
CALL
$2.69 Billion
104K N/A
NVO
Novo Nordisk A S
CALL
$2.22 Billion
40K
Q3 2025
Reduced 76.61%
NVO
Novo Nordisk A S
PUT
$2.03 Billion
36.5K
Q3 2025
Reduced 76.61%
INSM
Insmed Inc
CALL
$1.68 Billion
11.7K N/A
MDGL
Madrigal Pharmaceuticals, Inc.
CALL
$1.15 Billion
2.5K N/A
PCVX
Vaxcyte, Inc.
CALL
$1.13 Billion
31.5K N/A
APLS
Apellis Pharmaceuticals, Inc.
CALL
$917 Million
40.5K N/A
RVMD
Revolution Medicines, Inc.
PUT
$789 Million
16.9K
Q3 2025
Reduced 22.37%
INSM
Insmed Inc
PUT
$677 Million
4.7K N/A
SRRK
Scholar Rock Holding Corp
PUT
$667 Million
17.9K
Q3 2025
Added 24.34%
AVXL
Anavex Life Sciences Corp.
CALL
$552 Million
62K N/A
WVE
Wave Life Sciences Ltd.
CALL
$549 Million
75K
Q3 2025
New holding
BGNE
Bei Gene, Ltd.
CALL
$511 Million
1.5K N/A
BGNE
Bei Gene, Ltd.
PUT
$511 Million
1.5K N/A
ABUS
Arbutus Biopharma Corp
CALL
$372 Million
81.9K N/A
TECH
Bio Techne Corp
CALL
$367 Million
6.6K N/A
QURE
Uni Qure N.V.
PUT
$350 Million
6K
Q3 2025
New holding
CRSP
Crispr Therapeutics Ag
PUT
$324 Million
5K
Q3 2025
New holding
CRSP
Crispr Therapeutics Ag
CALL
$305 Million
4.7K
Q3 2025
New holding
INCY
Incyte Corp
PUT
$254 Million
3K N/A
INCY
Incyte Corp
CALL
$254 Million
3K N/A
TECH
Bio Techne Corp
PUT
$245 Million
4.4K N/A
ARDX
Ardelyx, Inc.
PUT
$214 Million
38.8K
Q1 2025
New holding
CAPR
Capricor Therapeutics, Inc.
CALL
$108 Million
15K N/A
SCPH
Sc Pharmaceuticals Inc.
CALL
$72.6 Million
12.8K N/A
REPL
Replimune Group, Inc.
CALL
$48.2 Million
11.5K N/A
LIFE
A Tyr Pharma Inc
CALL
$43.2 Million
60K N/A
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