Pictet Asset Management Holding Sa Biotechnology

Pictet Asset Management Holding Sa

$98.2 Billion
Q3 2025

Stock List

Stock	Market Cap.	Holding Value (Reported)	# of Shares.	Last Trade	Trade History
VRTX Vertex Pharmaceuticals Inc	$111B	$310 Million 0.32% of portfolio	791,458	Q3 2025 Added 7.56%
REGN Regeneron Pharmaceuticals, Inc.	$74.3B	$182 Million 0.19% of portfolio	323,370	Q3 2025 Added 6.33%
ALNY Alnylam Pharmaceuticals, Inc.	$55.3B	$177 Million 0.18% of portfolio	387,546	Q3 2025 Reduced 16.59%
INSM Insmed Inc	$26.2B	$164 Million 0.17% of portfolio	1,140,827	Q3 2025 Reduced 26.57%
UTHR United Therapeutics Corp	$21.2B	$135 Million 0.14% of portfolio	321,495	Q3 2025 Added 52.07%
ARGX Argenx Se	$50.2B	$125 Million 0.13% of portfolio	169,333	Q3 2025 Reduced 14.17%
IONS Ionis Pharmaceuticals Inc	$10.2B	$91.1 Million 0.09% of portfolio	1,393,124	Q3 2025 Added 128.89%
MDGL Madrigal Pharmaceuticals, Inc.	$9.05B	$88 Million 0.09% of portfolio	191,796	Q3 2025 Reduced 7.91%
PTCT Ptc Therapeutics, Inc.	$5.39B	$86.4 Million 0.09% of portfolio	1,407,974	Q3 2025 Added 35.2%

INCY Incyte Corp	$23.2B	$70.1 Million 0.07% of portfolio	826,284	Q3 2025 Reduced 24.57%
RYTM Rhythm Pharmaceuticals, Inc.	$5.54B	$69 Million 0.07% of portfolio	683,017	Q3 2025 Added 64.14%
CYTK Cytokinetics Inc	$6.25B	$63 Million 0.06% of portfolio	1,145,558	Q3 2025 Reduced 25.92%
RVMD Revolution Medicines, Inc.	$5.94B	$61.3 Million 0.06% of portfolio	1,311,741	Q3 2025 Added 29.62%
CRNX Crinetics Pharmaceuticals, Inc.	$2.34B	$61 Million 0.06% of portfolio	1,465,262	Q3 2025 Added 22.06%
BBIO Bridge Bio Pharma, Inc.	$9.84B	$58.9 Million 0.06% of portfolio	1,133,351	Q3 2025 Reduced 37.3%
RNA Avidity Biosciences, Inc.	$3.69B	$58.3 Million 0.06% of portfolio	1,338,091	Q3 2025 Added 38.29%
TGTX Tg Therapeutics, Inc.	$4.5B	$58.2 Million 0.06% of portfolio	1,609,551	Q3 2025 Reduced 15.62%
PTGX Protagonist Therapeutics, Inc	$4.15B	$54.6 Million 0.06% of portfolio	822,212	Q3 2025 Added 9.34%

FOLD Amicus Therapeutics, Inc.	$2.66B	$53.5 Million 0.05% of portfolio	6,788,164	Q3 2025 Added 73.72%
XENE Xenon Pharmaceuticals Inc.	$2.54B	$50.7 Million 0.05% of portfolio	1,262,579	Q3 2025 Reduced 14.37%
SRRK Scholar Rock Holding Corp	$1.95B	$49.4 Million 0.05% of portfolio	1,322,931	Q3 2025 Added 33.97%
BMRN Biomarin Pharmaceutical Inc	$10.2B	$48.2 Million 0.05% of portfolio	890,213	Q3 2025 Reduced 18.58%
AKRO Akero Therapeutics, Inc.	$2.52B	$44 Million 0.04% of portfolio	926,441	Q3 2025 Reduced 6.1%
AXSM Axsome Therapeutics, Inc.	$5.99B	$44 Million 0.04% of portfolio	362,138	Q3 2025 Reduced 12.07%
RARE Ultragenyx Pharmaceutical Inc.	$2.32B	$43.9 Million 0.04% of portfolio	1,458,187	Q3 2025 Reduced 14.22%
VERA Vera Therapeutics, Inc.	$766M	$41.7 Million 0.04% of portfolio	1,439,121	Q3 2025 Added 86.22%
MIRM Mirum Pharmaceuticals, Inc.	$2.63B	$39.7 Million 0.04% of portfolio	541,277	Q3 2025 Reduced 22.8%
PCVX Vaxcyte, Inc.	$2.87B	$37.1 Million 0.04% of portfolio	1,029,629	Q3 2025 Reduced 12.42%
KRYS Krystal Biotech, Inc.	$5.29B	$34.8 Million 0.04% of portfolio	196,904	Q3 2025 Added 50.84%
ACLX Arcellx, Inc.	$3.94B	$34.5 Million 0.04% of portfolio	420,805	Q3 2025 Added 9.83%
NUVL Nuvalent, Inc.	$4.15B	$33.3 Million 0.03% of portfolio	384,576	Q3 2025 Reduced 34.8%
SMMT Summit Therapeutics Inc.	$3.67B	$33.3 Million 0.03% of portfolio	1,604,163	Q3 2025 Reduced 25.87%
CLDX Celldex Therapeutics, Inc.	$1.2B	$31.4 Million 0.03% of portfolio	1,211,990	Q3 2025 Reduced 6.79%
ACAD Acadia Pharmaceuticals Inc	$3.89B	$31.2 Million 0.03% of portfolio	1,463,048	Q3 2025 Reduced 7.67%
MRUS Merus N.V.	$4.4B	$31.1 Million 0.03% of portfolio	330,228	Q3 2025 Reduced 63.92%
VKTX Viking Therapeutics, Inc.	$3.05B	$30.6 Million 0.03% of portfolio	1,196,305	Q3 2025 Reduced 37.59%
JAZZ Jazz Pharmaceuticals PLC	$8.84B	$28.8 Million 0.03% of portfolio	218,243	Q3 2025 Reduced 3.79%
IDYA Ideaya Biosciences, Inc.	$1.54B	$28.1 Million 0.03% of portfolio	1,032,999	Q3 2025 Reduced 42.77%
VRDN Viridian Therapeutics, Inc.\De	$1.15B	$22.6 Million 0.02% of portfolio	1,049,385	Q3 2025 Reduced 17.09%
KYMR Kymera Therapeutics, Inc.	$3.55B	$19.6 Million 0.02% of portfolio	346,817	Q3 2025 Added 6,139.96%
MRNA Moderna, Inc.	$9.69B	$19 Million 0.02% of portfolio	734,489	Q3 2025 Added 7.62%
IMVT Immunovant, Inc.	$3.55B	$18.6 Million 0.02% of portfolio	676,577	Q3 2025 Reduced 43.08%
NRIX Nurix Therapeutics, Inc.	$603M	$18.3 Million 0.02% of portfolio	1,980,540	Q3 2025 Reduced 0.91%
DAWN Day One Biopharmaceuticals, Inc.	$646M	$16.7 Million 0.02% of portfolio	2,373,133	Q3 2025 Reduced 36.25%
TVTX Travere Therapeutics, Inc.	$2.21B	$16.4 Million 0.02% of portfolio	684,384	Q3 2025 Added 14.89%
OLMA Olema Pharmaceuticals, Inc.	$351M	$15.8 Million 0.02% of portfolio	1,636,372	Q3 2025 Reduced 12.91%
EXEL Exelixis, Inc.	$13.4B	$15.4 Million 0.02% of portfolio	372,399	Q3 2025 Reduced 2.37%
ASND Ascendis Pharma A/S	$11.4B	$15.3 Million 0.02% of portfolio	77,058	Q3 2025 Reduced 9.91%
JANX Janux Therapeutics, Inc.	$1.22B	$14.5 Million 0.01% of portfolio	594,831	Q3 2025 Reduced 11.42%
RPRX Royalty Pharma PLC	$17.1B	$13.3 Million 0.01% of portfolio	376,049	Q3 2025 Reduced 22.65%

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