Rothschild Investment LLC Biotechnology

Rothschild Investment LLC

$1.77 Trillion
Q3 2025

Stock List

Stock	Market Cap.	Holding Value (Reported)	# of Shares.	Last Trade	Trade History
NUVB Nuvation Bio Inc.	$1.06B	$962,000 0.0% of portfolio	260	Q3 2025 Added 100.0%
XNCR Xencor Inc	$891M	$938,000 0.0% of portfolio	80	Q3 2025 Reduced 62.79%
URGN Uro Gen Pharma Ltd.	$553M	$898,000 0.0% of portfolio	45	Q3 2025 Reduced 35.71%
IMVT Immunovant, Inc.	$3.55B	$887,000 0.0% of portfolio	55	Q3 2025 Reduced 65.63%
IONS Ionis Pharmaceuticals Inc	$10.2B	$850,000 0.0% of portfolio	13	Q3 2025 Added 30.0%
ERAS Erasca, Inc.	$315M	$839,000 0.0% of portfolio	385	Q2 2025 Added 57.14%
ATXS Astria Therapeutics, Inc.	$191M	$837,000 0.0% of portfolio	115	Q2 2025 Reduced 25.81%
ARCT Arcturus Therapeutics Holdings Inc.	$193M	$829,000 0.0% of portfolio	45	Q2 2025 Reduced 18.18%
CRMD Cor Medix Inc.	$467M	$814,000 0.0% of portfolio	70	Q3 2025 Reduced 58.82%

TYRA Tyra Biosciences, Inc.	$652M	$769,000 0.0% of portfolio	55	Q2 2025 Added 1,000.0%
IOVA Iovance Biotherapeutics, Inc.	$390M	$760,000 0.0% of portfolio	350	Q3 2025 Added 59.09%
ROIV Roivant Sciences Ltd.	$14.3B	$757,000 0.0% of portfolio	50	Q3 2025 Added 42.86%
RPRX Royalty Pharma PLC	$17.1B	$741,000 0.0% of portfolio	21	Q3 2025 Added 425.0%
ALDX Aldeyra Therapeutics, Inc.	$296M	$705,000 0.0% of portfolio	135	Q3 2025 Added 58.82%
ALEC Alector, Inc.	$102M	$648,000 0.0% of portfolio	219	Q3 2025 Reduced 42.37%
BEAM Beam Therapeutics Inc.	$1.55B	$607,000 0.0% of portfolio	25	Q3 2025 Reduced 79.17%
INSM Insmed Inc	$26.2B	$576,000 0.0% of portfolio	4	Q3 2025 New
ORIC Oric Pharmaceuticals, Inc.	$518M	$540,000 0.0% of portfolio	45	Q3 2025 Reduced 50.0%

REPL Replimune Group, Inc.	$443M	$524,000 0.0% of portfolio	125	Q3 2025 Added 19.05%
KMPH Kempharm, Inc	$170M	$523,000 0.0% of portfolio	55	Q3 2025 Reduced 38.89%
EDIT Editas Medicine, Inc.	$179M	$521,000 0.0% of portfolio	150	Q3 2025 Reduced 50.0%
ANNX Annexon, Inc.	$136M	$503,000 0.0% of portfolio	165	Q2 2025 Reduced 60.71%
CDXS Codexis, Inc.	$108M	$500,000 0.0% of portfolio	205	Q2 2025 Added 192.86%
SLDB Solid Biosciences Inc.	$31.7M	$463,000 0.0% of portfolio	75	Q2 2025 New
CMPX Compass Therapeutics, Inc.	$494M	$420,000 0.0% of portfolio	120	Q2 2025 New
GLUE Monte Rosa Therapeutics, Inc.	$671M	$371,000 0.0% of portfolio	50	Q3 2025 Reduced 52.38%
LRMR Larimar Therapeutics, Inc.	$146M	$355,000 0.0% of portfolio	110	Q2 2025 Added 214.29%
SBTX Silverback Therapeutics, Inc.	$0	$352,000 0.0% of portfolio	35	Q3 2025 Reduced 78.79%
ABSI Absci Corp	$266M	$319,000 0.0% of portfolio	105	Q2 2025 Reduced 34.38%
RXRX Recursion Pharmaceuticals, Inc.	$747M	$293,000 0.0% of portfolio	60	Q3 2025 Reduced 90.0%
CDXC Chroma Dex Corp.	$420M	$280,000 0.0% of portfolio	30	Q3 2025 Reduced 73.91%
APLS Apellis Pharmaceuticals, Inc.	$2.23B	$272,000 0.0% of portfolio	12	Q3 2025 New
ATAI Atai Life Sciences N.V.	$664M	$265,000 0.0% of portfolio	50	Q2 2024 New
AVIR Atea Pharmaceuticals, Inc.	$246M	$247,000 0.0% of portfolio	85	Q2 2025 New
AURA Aura Biosciences, Inc.	$162M	$216,000 0.0% of portfolio	35	Q3 2025 Reduced 53.33%
CGEM Cullinan Oncology, Inc.	$390M	$178,000 0.0% of portfolio	30	Q2 2025 Reduced 87.76%
TNGX Tango Therapeutics, Inc.	$720M	$168,000 0.0% of portfolio	20	Q3 2025 New
IBRX Immunity Bio, Inc.	$833M	$148,000 0.0% of portfolio	60	Q3 2025 Reduced 92.05%
XOMA Xoma Corp	$371M	$116,000 0.0% of portfolio	3	Q1 2025 New
HRTX Heron Therapeutics, Inc.	$131M	$40,000 0.0% of portfolio	32	Q3 2025 Reduced 86.38%
SMMT Summit Therapeutics Inc.	$3.67B	$21,000 0.0% of portfolio	1	Q3 2025 New

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