Baker Bros. Advisors LP Purchases and Sells in Q3 2025

Baker Bros. Advisors LP

$12.3 Billion
Q3 2025

Top Buys

Incresed Positions

14 operations

Stock	Shares change	Price Range	Shares Held	Trade History
INCY	388 + 0.0%	$67.27 - $86.96 $26.1K - $33.7K	30.7M $2.61B
MDGL	166K + 8.38%	$287.52 - $458.66 $47.6M - $76M	2.14M $982M
CELC	2.47M + 45.23%	$12.58 - $62.68 $31M - $155M	7.92M $389M
RVMD	90.4K + 0.97%	$34.7 - $46.7 $3.14M - $4.22M	9.46M $442M
ALKS	1.68M + 26.22%	$26.13 - $30.46 $43.9M - $51.2M	8.09M $243M
IMTX	1.93M + 18.93%	$5.09 - $8.52 $9.8M - $16.4M	12.1M $103M

New Holdings

12 operations

Stock	Shares change	Price Range	Shares Held	Trade History
IONS	567K New	$39.94 - $65.42 $22.6M - $37.1M	567K $37.1M
RNA	625K New	$28.46 - $50.36 $17.8M - $31.5M	625K $27.2M
PHVS	375K New	$17.25 - $25.36 $6.47M - $9.51M	375K $9.36M
VKTX	366K New	$23.09 - $42.09 $8.45M - $15.4M	366K $9.35M
HRTX	4.25M New	$1.21 - $2.23 $5.14M - $9.48M	4.25M $5.44M
VTYX	1.02M New	$2.02 - $3.27 $2.07M - $3.35M	1.02M $3.18M

Top Sells

Reduced Positions

5 operations

Stock	Shares change	Price Range	Shares Held	Trade History
CERS	-2.88M - 22.32%	$1.16 - $1.6 $3.34M - $4.6M	10M $15.9M
Contineum Therapeutics, Inc.	-235K - 75.15%	N/A	77.7K $0
KALA BIO, Inc.	-217K - 18.04%	N/A	985K $0
Structure Therapeutics Inc.	-953K - 37.97%	N/A	1.56M $0
INSM	-1.01M - 13.09%	$96.14 - $147.2 $97M - $149M	6.7M $965M

Activity Summary All Purchases 26 New Holdings 12 Increased Positions 14 All Sells 5 Reductions 5 Sold out 0 Calls 0 Puts 0

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