California State Teachers Retirement System Biotechnology

California State Teachers Retirement System

$83.3 Billion
Q4 2024

Stock List

Stock	Market Cap.	Holding Value (Reported)	# of Shares.	Last Trade	Trade History
VRTX Vertex Pharmaceuticals Inc	$124B	$161 Million 0.19% of portfolio	400,670	Q2 2024 Added 3.8%
REGN Regeneron Pharmaceuticals, Inc.	$68B	$120 Million 0.14% of portfolio	167,889	Q2 2024 Added 3.48%
ALNY Alnylam Pharmaceuticals, Inc.	$33.2B	$46.2 Million 0.06% of portfolio	196,362	Q2 2024 Reduced 1.41%
RPRX Royalty Pharma PLC	$13.6B	$22.4 Million 0.03% of portfolio	876,268	Q2 2024 Reduced 16.53%
UTHR United Therapeutics Corp	$14B	$22.2 Million 0.03% of portfolio	62,979	Q2 2024 Added 15.54%
MRNA Moderna, Inc.	$11.1B	$20.8 Million 0.03% of portfolio	500,867	Q2 2024 Added 3.93%
BMRN Biomarin Pharmaceutical Inc	$13.1B	$18 Million 0.02% of portfolio	273,761	Q2 2024 Reduced 0.19%
TECH Bio Techne Corp	$2.3B	$18 Million 0.02% of portfolio	249,350	Q2 2024 Reduced 2.68%
INCY Incyte Corp	$13.5B	$16.6 Million 0.02% of portfolio	241,033	Q2 2024 Reduced 0.79%
INSM Insmed Inc	$10.6B	$10.6 Million 0.01% of portfolio	153,343	Q2 2024 Reduced 9.53%
SRPT Sarepta Therapeutics, Inc.	$5.59B	$9.81 Million 0.01% of portfolio	80,662	Q2 2024 Added 2.83%
PCVX Vaxcyte, Inc.	$2.24B	$8.6 Million 0.01% of portfolio	105,052	Q2 2024 Reduced 13.11%
EXEL Exelixis, Inc.	$11.9B	$8.06 Million 0.01% of portfolio	241,973	Q2 2024 Added 7.9%
JAZZ Jazz Pharmaceuticals PLC	$7.78B	$6.78 Million 0.01% of portfolio	55,015	Q2 2024 Added 5.91%
HALO Halozyme Therapeutics, Inc.	$8.89B	$5.66 Million 0.01% of portfolio	118,318	Q2 2024 Added 4.75%
BPMC Blueprint Medicines Corp	$5.3B	$5.17 Million 0.01% of portfolio	59,259	Q2 2024 Reduced 3.56%
RVMD Revolution Medicines, Inc.	$3.28B	$4.94 Million 0.01% of portfolio	113,036	Q2 2024 Added 1.99%
CYTK Cytokinetics Inc	$4.07B	$4.93 Million 0.01% of portfolio	104,718	Q2 2024 Reduced 6.53%
IONS Ionis Pharmaceuticals Inc	$4.28B	$4.68 Million 0.01% of portfolio	133,902	Q2 2024 Reduced 3.5%
ROIV Roivant Sciences Ltd.	$7.31B	$4.63 Million 0.01% of portfolio	391,703	Q2 2024 Reduced 9.68%
CORT Corcept Therapeutics Inc	$5.85B	$4.38 Million 0.01% of portfolio	86,974	Q2 2024 Added 3.57%
TGTX Tg Therapeutics, Inc.	$5.79B	$4.12 Million 0.0% of portfolio	137,002	Q2 2024 Added 4.18%
CRNX Crinetics Pharmaceuticals, Inc.	$1.8B	$3.9 Million 0.0% of portfolio	76,264	Q2 2024 Reduced 14.07%
MDGL Madrigal Pharmaceuticals, Inc.	$5.61B	$3.87 Million 0.0% of portfolio	12,546	Q2 2024 Added 0.9%
VKTX Viking Therapeutics, Inc.	$1.97B	$3.77 Million 0.0% of portfolio	93,794	Q2 2024 Added 3.04%
ADMA Adma Biologics, Inc.	$3.98B	$3.73 Million 0.0% of portfolio	217,391	Q2 2024 Reduced 0.88%
RARE Ultragenyx Pharmaceutical Inc.	$2.65B	$3.28 Million 0.0% of portfolio	78,051	Q2 2024 Reduced 5.91%
KRYS Krystal Biotech, Inc.	$4.72B	$3.19 Million 0.0% of portfolio	20,388	Q2 2024 Reduced 9.63%
BBIO Bridge Bio Pharma, Inc.	$5.2B	$3.17 Million 0.0% of portfolio	115,655	Q2 2024 Reduced 5.05%
PTCT Ptc Therapeutics, Inc.	$3.88B	$2.95 Million 0.0% of portfolio	65,254	Q2 2024 Added 4.0%
VCYT Veracyte, Inc.	$2.16B	$2.84 Million 0.0% of portfolio	71,834	Q2 2024 Added 1.62%
CRSP Crispr Therapeutics Ag	$2.65B	$2.75 Million 0.0% of portfolio	69,742	Q2 2024 Added 4.53%
NUVL Nuvalent, Inc.	$3.14B	$2.62 Million 0.0% of portfolio	33,442	Q2 2024 Reduced 13.67%
VCEL Vericel Corp	$2.1B	$2.52 Million 0.0% of portfolio	45,857	Q2 2024 Reduced 1.55%
AXSM Axsome Therapeutics, Inc.	$5.08B	$2.5 Million 0.0% of portfolio	29,594	Q2 2024 Added 3.23%
RNA Avidity Biosciences, Inc.	$1.65B	$2.46 Million 0.0% of portfolio	84,552	Q2 2024 Reduced 6.64%
DNLI Denali Therapeutics Inc.	$1.98B	$2.45 Million 0.0% of portfolio	120,174	Q2 2024 Reduced 3.51%
RYTM Rhythm Pharmaceuticals, Inc.	$3.05B	$2.43 Million 0.0% of portfolio	43,533	Q2 2024 Added 2.81%
SRRK Scholar Rock Holding Corp	$1.7B	$2.43 Million 0.0% of portfolio	56,269	Q2 2024 Reduced 22.15%
ACLX Arcellx, Inc.	$2.98B	$2.36 Million 0.0% of portfolio	30,961	Q2 2024 Added 3.56%
APLS Apellis Pharmaceuticals, Inc.	$2.67B	$2.26 Million 0.0% of portfolio	70,688	Q2 2024 Added 11.34%
XENE Xenon Pharmaceuticals Inc.	$2.13B	$2.18 Million 0.0% of portfolio	55,492	Q2 2024 Added 4.77%
CPRX Catalyst Pharmaceuticals, Inc.	$2.54B	$2.09 Million 0.0% of portfolio	100,230	Q2 2024 Added 4.47%
SWTX Spring Works Therapeutics, Inc.	$2.96B	$2.03 Million 0.0% of portfolio	56,220	Q2 2024 Reduced 2.1%
FOLD Amicus Therapeutics, Inc.	$2.36B	$2.01 Million 0.0% of portfolio	213,265	Q2 2024 Added 4.13%
ARWR Arrowhead Pharmaceuticals, Inc.	$1.46B	$1.98 Million 0.0% of portfolio	105,154	Q2 2024 Added 14.76%
JANX Janux Therapeutics, Inc.	$1.21B	$1.97 Million 0.0% of portfolio	36,735	Q2 2024 Reduced 43.55%
ACAD Acadia Pharmaceuticals Inc	$2.76B	$1.87 Million 0.0% of portfolio	101,658	Q2 2024 Added 3.85%
IDYA Ideaya Biosciences, Inc.	$820M	$1.84 Million 0.0% of portfolio	71,726	Q2 2024 Reduced 12.43%
LGND Ligand Pharmaceuticals Inc	$1.82B	$1.82 Million 0.0% of portfolio	17,014	Q2 2024 Reduced 3.43%

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