D. E. Shaw & Co., Inc. Biotechnology

D. E. Shaw & Co., Inc.

  • $156 Billion
  • Q3 2025

Stock List

Stock Option Type Value Options Held Last Trade Trade History
NVO
Novo Nordisk A S
PUT
$139 Million
2.51M
Q3 2025
New holding
MRNA
Moderna, Inc.
PUT
$112 Million
4.33M
Q3 2025
Reduced 17.65%
ARGX
Argenx Se
CALL
$55.2 Million
74.9K
Q3 2025
Added 22.52%
MRNA
Moderna, Inc.
CALL
$35.6 Million
1.38M
Q3 2025
Reduced 17.65%
MDGL
Madrigal Pharmaceuticals, Inc.
CALL
$24.7 Million
53.9K
Q3 2025
Reduced 14.11%
REGN
Regeneron Pharmaceuticals, Inc.
CALL
$24.6 Million
43.7K
Q3 2025
Added 10.82%
CRSP
Crispr Therapeutics Ag
CALL
$23.4 Million
360K
Q3 2024
Added 4.23%
ALNY
Alnylam Pharmaceuticals, Inc.
CALL
$14.5 Million
31.9K
Q3 2025
Added 84.17%
VRTX
Vertex Pharmaceuticals Inc
CALL
$13.9 Million
35.6K
Q3 2025
Reduced 83.35%
NVO
Novo Nordisk A S
CALL
$12 Million
217K
Q3 2025
New holding
REGN
Regeneron Pharmaceuticals, Inc.
PUT
$11.2 Million
20K
Q3 2025
Added 10.82%
INSM
Insmed Inc
CALL
$8.89 Million
61.7K
Q3 2025
Added 65.3%
QURE
Uni Qure N.V.
CALL
$8.24 Million
141K
Q3 2025
Added 18.18%
ARGX
Argenx Se
PUT
$7.38 Million
10K
Q3 2025
Added 22.52%
VRTX
Vertex Pharmaceuticals Inc
PUT
$4.86 Million
12.4K
Q3 2025
Reduced 83.35%
CRSP
Crispr Therapeutics Ag
PUT
$4.55 Million
70.2K
Q3 2024
Added 4.23%
CYTK
Cytokinetics Inc
CALL
$4 Million
72.7K
Q3 2025
Reduced 28.72%
CORT
Corcept Therapeutics Inc
PUT
$3.74 Million
45K
Q3 2025
Reduced 13.23%
VKTX
Viking Therapeutics, Inc.
CALL
$3.53 Million
138K
Q3 2025
Reduced 21.47%
BMRN
Biomarin Pharmaceutical Inc
PUT
$3.25 Million
60K
Q3 2025
Reduced 75.32%
BNTX
Bio N Tech Se
PUT
$3.16 Million
32K
Q1 2025
Added 70.33%
TGTX
Tg Therapeutics, Inc.
CALL
$3.1 Million
85.8K
Q3 2025
Added 96.4%
BNTX
Bio N Tech Se
CALL
$2.56 Million
26K
Q1 2025
Added 70.33%
NVAX
Novavax Inc
PUT
$2.38 Million
275K
Q3 2025
Added 8.45%
NVAX
Novavax Inc
CALL
$2.35 Million
271K
Q3 2025
Added 8.45%
SRPT
Sarepta Therapeutics, Inc.
PUT
$1.61 Million
83.6K
Q3 2025
Reduced 55.19%
INSM
Insmed Inc
PUT
$1.44 Million
10K
Q3 2025
Added 65.3%
BEAM
Beam Therapeutics Inc.
CALL
$1.36 Million
55.9K
Q2 2024
New holding
UTHR
United Therapeutics Corp
CALL
$1.17 Million
2.8K
Q3 2025
Added 199.48%
VRNA
Verona Pharma PLC
CALL
$1.07 Million
10K
Q3 2025
Reduced 76.18%
CYTK
Cytokinetics Inc
PUT
$1.01 Million
18.4K
Q3 2025
Reduced 28.72%
ASND
Ascendis Pharma A/S
CALL
$994,000
5K
Q3 2025
Reduced 50.1%
AXSM
Axsome Therapeutics, Inc.
CALL
$801,000
6.6K
Q3 2025
Added 47.58%
MLTX
Moon Lake Immunotherapeutics
CALL
$661,000
92.3K
Q4 2023
New holding
CAPR
Capricor Therapeutics, Inc.
CALL
$471,000
65K
Q3 2025
Added 48.56%
ALNY
Alnylam Pharmaceuticals, Inc.
PUT
$410,000
900
Q3 2025
Added 84.17%
BGNE
Bei Gene, Ltd.
CALL
$362,000
1.6K
Q2 2025
Added 12.54%
APLS
Apellis Pharmaceuticals, Inc.
PUT
$339,000
15K
Q3 2025
Added 81.94%
APLS
Apellis Pharmaceuticals, Inc.
CALL
$314,000
13.9K
Q3 2025
Added 81.94%
LGND
Ligand Pharmaceuticals Inc
CALL
$283,000
1.6K
Q3 2025
Added 144.92%
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