Dafna Capital Management LLC Portfolio Holdings

Dafna Capital Management LLC

  • $368 Million
  • Q3 2025

Dafna Capital Management LLC has filed its 13F form on November 14, 2025 for Q3 2025 where it was disclosed a total value porftolio of $368 Million distributed in 75 stocks.

Among their holdings, we can observe that their the top five positions include companies like: Stereotaxis, Inc. with a value of $41.9M, Spdr Ser Tr Spdr S&P Biotech E with a value of $40.2M, Revolution Medicines, Inc. with a value of $30.7M, Cytokinetics Inc with a value of $21.7M, and Atri Cure, Inc. with a value of $20.9M.

Examining the 13F form we can see an increase of $24.1M in the current position value, from $344M to 368M.

Dafna Capital Management LLC is based out at Los Angeles, CA

Below you can find more details about Dafna Capital Management LLC portfolio as well as his latest detailed transactions.

Portfolio value $368 Million
Healthcare: $313 Million
ETFs: $55 Million

Stock Holdings Table

Stock Market Cap. Holding Value (Reported) # of Shares. Last Trade Trade History
$165M
$41.9 Million 11.38% of portfolio
13,680,554
Q1 2018 Added 896.5%
$0
$40.2 Million 10.93% of portfolio
401,505
Q3 2025 Reduced 3.37%
$5.94B
$30.7 Million 8.34% of portfolio
657,176
Q3 2025 Reduced 2.95%
$6.25B
$21.7 Million 5.9% of portfolio
394,940
Q3 2025 Reduced 0.79%
$1.53B
$20.9 Million 5.67% of portfolio
592,273
Q1 2025 Reduced 7.7%
$4.4B
$20.8 Million 5.64% of portfolio
220,451
Q3 2025 Reduced 44.72%
$0
$14.8 Million 4.02% of portfolio
102,500
Q1 2022 Added 150.61%
$1.54B
$14.7 Million 3.99% of portfolio
539,923
Q3 2025 Reduced 12.79%
$1B
$13.2 Million 3.6% of portfolio
742,282
Q3 2025 Added 0.07%
$2.54B
$11.6 Million 3.14% of portfolio
287,939
Q2 2025 Added 5.19%
$13.9B
$9.91 Million 2.69% of portfolio
70,615
Q2 2025 Reduced 1.4%
$1.45B
$8.54 Million 2.32% of portfolio
627,626
Q2 2025 Added 0.4%
$940M
$7.71 Million 2.09% of portfolio
500,702
Q3 2025 Reduced 7.89%
$646M
$7.04 Million 1.91% of portfolio
999,163
Q3 2025 Added 13.65%
$363M
$6.93 Million 1.88% of portfolio
811,046
Q2 2025 Added 14.06%
$11.4B
$6.6 Million 1.79% of portfolio
33,177
Q3 2025 Reduced 54.35%
$328M
$5.11 Million 1.39% of portfolio
422,731
Q3 2025 Reduced 27.34%
$158M
$4.95 Million 1.34% of portfolio
605,625
Q2 2025 Added 32.21%
$2.06B
$4.51 Million 1.23% of portfolio
130,175
Q4 2023 Added 116.33%
$22.4B
$4.41 Million 1.2% of portfolio
65,552
Q1 2024 Reduced 2.96%
$1.2B
$4.31 Million 1.17% of portfolio
355,208
Q3 2025 Added 20.73%
$749M
$4.1 Million 1.11% of portfolio
463,368
Q1 2025 Added 3.35%
$4.77B
$4.04 Million 1.1% of portfolio
134,748
Q3 2025 Added 29.88%
$1.05B
$3.99 Million 1.08% of portfolio
169,791
Q3 2025 Reduced 66.18%
$494M
$3.55 Million 0.96% of portfolio
946,661
Q3 2025 Added 79.75%
$1.44B
$3.47 Million 0.94% of portfolio
213,736
Q3 2025 Reduced 10.25%
$156M
$3.31 Million 0.9% of portfolio
1,567,561
Q4 2024 Added 73.1%
$146M
$3.32 Million 0.9% of portfolio
1,027,764
Q3 2025 Added 176.7%
$288M
$2.87 Million 0.78% of portfolio
512,589
Q3 2025 Added 260.98%
$2.34B
$2.45 Million 0.66% of portfolio
168,500
Q2 2025 Added 31.74%
$102M
$2.36 Million 0.64% of portfolio
798,351
Q3 2025 Reduced 12.55%
$191M
$2.31 Million 0.63% of portfolio
319,775
Q3 2025 Reduced 1.54%
$18.8M
$2.12 Million 0.58% of portfolio
1,441,029
Q4 2024 New
$23.1B
$2.12 Million 0.58% of portfolio
6,870
Q3 2025 Reduced 30.61%
$100M
$1.98 Million 0.54% of portfolio
1,222,358
Q4 2022 Added 29.79%
$778M
$2 Million 0.54% of portfolio
235,000
Q3 2025 Reduced 4.08%
$177M
$1.71 Million 0.46% of portfolio
1,380,118
Q1 2025 Added 11.29%
$3.05B
$1.65 Million 0.45% of portfolio
64,516
Q4 2024 Reduced 48.64%
$1.32B
$1.66 Million 0.45% of portfolio
218,255
Q2 2025 Reduced 60.9%
$10.7B
$1.38 Million 0.37% of portfolio
11,000
Q1 2025 Added 100.0%
$2.49B
$1.28 Million 0.35% of portfolio
17,200
Q3 2025 New
$445M
$1.28 Million 0.35% of portfolio
80,716
Q3 2025 Reduced 38.06%
$518M
$1.25 Million 0.34% of portfolio
104,671
Q3 2025 Reduced 22.62%
$153M
$1.13 Million 0.31% of portfolio
307,070
Q3 2025 Reduced 34.8%
$27.7M
$852,000 0.23% of portfolio
1,704,232
Q2 2024 Added 30.35%
$262M
$849,000 0.23% of portfolio
56,966
Q3 2025 Reduced 55.2%
$315M
$763,000 0.21% of portfolio
350,000
Q2 2025 Added 2.94%
$25B
$690,000 0.19% of portfolio
7,000
Q2 2025 Reduced 33.33%
$1.2B
$634,000 0.17% of portfolio
24,518
Q3 2025 New

Summary

  • Portfolio
  • No. of Stocks 75
  • Current Value $368 Million
  • Prior Value $344 Million
  • Filing
  • Period Q3 2025
  • Filing Date November 14, 2025
  • Form Type 13F-HR
  • Activity in Q3 2025
  • New Purchases 7 stocks
  • Additional Purchases 10 stocks
  • Sold out of 0 stocks
  • Reduced holdings in 24 stocks
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