David A. Siegel Castle Biosciences Inc Transaction History

Two Sigma Advisers, LP

$47 Billion
Q3 2025

A detailed history of David A. Siegel (Two Sigma Advisers, LP) transactions in Castle Biosciences Inc stock. As of the latest transaction made, Two Sigma Advisers, LP holds 9,900 shares of CSTL stock, worth $331,155. This represents 0.0% of its overall portfolio holdings.

Number of Shares

9,900

Previous 12,000 17.5%

Holding current value

$331,155

Previous $245,000 8.16%

% of portfolio

0.0%

Previous 0.0%

23 transactions

Quarter	Operation	Price Per share	shares change	shares Held
Q3 2025 Nov 14, 2025	SELL	$14.65 - $24.65 $30,765 - $51,765	-2,100 Reduced 17.5%	9,900 $225,000
Q2 2025 Aug 14, 2025	SELL	$15.8 - $21.98 $903,760 - $1.26 Million	-57,200 Reduced 82.66%	12,000 $245,000
Q1 2025 May 15, 2025	BUY	$18.76 - $32.72 $1.08 Million - $1.89 Million	57,700 Added 501.74%	69,200 $1.39 Million
Q4 2024 Feb 14, 2025	BUY	$26.52 - $34.67 $304,980 - $398,705	11,500 New	11,500 $306,000
Q1 2024 May 15, 2024	SELL	$18.06 - $25.3 $236,585 - $331,430	-13,100 Reduced 40.81%	19,000 $420,000

Q4 2023 Feb 14, 2024	SELL	$12.19 - $22.43 $297,436 - $547,292	-24,400 Reduced 43.19%	32,100 $692,000
Q3 2023 Nov 14, 2023	SELL	$13.28 - $20.3 $484,720 - $740,950	-36,500 Reduced 39.25%	56,500 $954,000
Q2 2023 Aug 14, 2023	SELL	$11.66 - $26.0 $225,038 - $501,800	-19,300 Reduced 17.19%	93,000 $1.28 Million
Q1 2023 May 15, 2023	SELL	$19.47 - $28.49 $385,506 - $564,102	-19,800 Reduced 14.99%	112,300 $2.55 Million
Q4 2022 Feb 14, 2023	SELL	$18.08 - $30.0 $385,103 - $639,000	-21,300 Reduced 13.89%	132,100 $3.11 Million
Q3 2022 Nov 14, 2022	SELL	$22.51 - $34.32 $42,769 - $65,208	-1,900 Reduced 1.22%	153,400 $4 Million
Q2 2022 Aug 15, 2022	BUY	$16.0 - $45.99 $2.1 Million - $6.05 Million	131,500 Added 552.52%	155,300 $3.41 Million
Q1 2022 May 16, 2022	SELL	$33.17 - $46.98 $2.91 Million - $4.12 Million	-87,700 Reduced 78.65%	23,800 $1.07 Million
Q4 2021 Feb 14, 2022	BUY	$39.06 - $67.58 $1.24 Million - $2.14 Million	31,700 Added 39.72%	111,500 $4.78 Million
Q3 2021 Nov 15, 2021	BUY	$60.13 - $77.6 $1.74 Million - $2.25 Million	29,000 Added 57.09%	79,800 $5.31 Million
Q2 2021 Aug 16, 2021	SELL	$50.07 - $76.78 $565,791 - $867,614	-11,300 Reduced 18.2%	50,800 $3.73 Million
Q1 2021 May 17, 2021	BUY	$58.92 - $97.33 $2.18 Million - $3.6 Million	37,000 Added 147.41%	62,100 $4.25 Million
Q4 2020 Feb 16, 2021	BUY	$43.6 - $73.05 $579,880 - $971,565	13,300 Added 112.71%	25,100 $1.69 Million
Q3 2020 Nov 16, 2020	SELL	$38.47 - $52.03 $96,175 - $130,075	-2,500 Reduced 17.48%	11,800 $607,000
Q2 2020 Aug 14, 2020	BUY	$27.28 - $43.01 $21,824 - $34,408	800 Added 5.93%	14,300 $539,000
Q1 2020 May 15, 2020	SELL	$23.08 - $35.53 $20,772 - $31,977	-900 Reduced 6.25%	13,500 $402,000
Q4 2019 Feb 14, 2020	SELL	$15.74 - $35.04 $31,480 - $70,080	-2,000 Reduced 12.2%	14,400 $495,000
Q3 2019 Nov 14, 2019	BUY	$18.09 - $27.92 $296,676 - $457,888	16,400 New	16,400 $297,000

Others Institutions Holding CSTL

# of Institutions

185

Shares Held

27M

Call Options Held

42.2K

Put Options Held

9.3K

View Full List

About CASTLE BIOSCIENCES INC

Ticker CSTL
Exchange NASDAQ
Sector Healthcare
Industry Diagnostics & Research
Shares Outstandng 26,297,000
Market Cap $880M
Description
Castle Biosciences, Inc., a commercial-stage diagnostics company, focuses to provide diagnostic and prognostic testing services for dermatological cancers. Its lead product is DecisionDx-Melanoma, a multi-gene expression profile (GEP) test to identify the risk of metastasis for patients diagnosed with invasive cutaneous melanoma. The company als...

More about CSTL

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