David A. Siegel Fulcrum Therapeutics, Inc. Transaction History

Two Sigma Advisers, LP

$47 Billion
Q3 2025

A detailed history of David A. Siegel (Two Sigma Advisers, LP) transactions in Fulcrum Therapeutics, Inc. stock. As of the latest transaction made, Two Sigma Advisers, LP holds 31,500 shares of FULC stock, worth $273,105. This represents 0.0% of its overall portfolio holdings.

Number of Shares

31,500

Previous 82,100 61.63%

Holding current value

$273,105

Previous $564,000 51.42%

% of portfolio

0.0%

Previous 0.0%

17 transactions

Quarter	Operation	Price Per share	shares change	shares Held
Q3 2025 Nov 14, 2025	SELL	$6.34 - $8.84 $320,804 - $447,304	-50,600 Reduced 61.63%	31,500 $274,000
Q2 2025 Aug 14, 2025	SELL	$2.51 - $7.38 $491,206 - $1.44 Million	-195,700 Reduced 70.45%	82,100 $564,000
Q1 2025 May 15, 2025	SELL	$2.88 - $5.08 $189,504 - $334,264	-65,800 Reduced 19.15%	277,800 $800,000
Q4 2024 Feb 14, 2025	SELL	$2.97 - $4.84 $114,642 - $186,824	-38,600 Reduced 10.1%	343,600 $1.61 Million
Q3 2024 Nov 14, 2024	SELL	$3.18 - $9.74 $576,534 - $1.77 Million	-181,300 Reduced 32.17%	382,200 $1.36 Million

Q2 2024 Aug 14, 2024	BUY	$5.98 - $9.31 $856,934 - $1.33 Million	143,300 Added 34.1%	563,500 $3.49 Million
Q1 2024 May 15, 2024	SELL	$6.7 - $12.0 $509,200 - $912,000	-76,000 Reduced 15.32%	420,200 $3.97 Million
Q4 2023 Feb 14, 2024	SELL	$3.18 - $6.86 $82,044 - $176,988	-25,800 Reduced 4.94%	496,200 $3.35 Million
Q3 2023 Nov 14, 2023	SELL	$3.25 - $6.08 $238,225 - $445,664	-73,300 Reduced 12.31%	522,000 $2.32 Million
Q2 2023 Aug 14, 2023	BUY	$2.26 - $3.8 $751,901 - $1.26 Million	332,700 Added 126.69%	595,300 $1.96 Million
Q1 2023 May 15, 2023	BUY	$2.83 - $13.99 $562,038 - $2.78 Million	198,600 Added 310.31%	262,600 $748,000
Q4 2022 Feb 14, 2023	BUY	$5.01 - $8.35 $68,637 - $114,395	13,700 Added 27.24%	64,000 $465,000
Q3 2022 Nov 14, 2022	SELL	$4.92 - $9.1 $300,120 - $555,100	-61,000 Reduced 54.81%	50,300 $407,000
Q2 2022 Aug 15, 2022	BUY	$4.2 - $24.0 $108,360 - $619,200	25,800 Added 30.18%	111,300 $545,000
Q1 2022 May 16, 2022	SELL	$9.96 - $23.65 $2.92 Million - $6.94 Million	-293,600 Reduced 77.45%	85,500 $2.02 Million
Q4 2021 Feb 14, 2022	BUY	$14.0 - $28.44 $3.32 Million - $6.74 Million	236,900 Added 166.6%	379,100 $6.71 Million
Q3 2021 Nov 15, 2021	BUY	$7.28 - $30.97 $1.04 Million - $4.4 Million	142,200 New	142,200 $4.01 Million

Others Institutions Holding FULC

# of Institutions

133

Shares Held

55.4M

Call Options Held

176K

Put Options Held

13.5K

View Full List

About Fulcrum Therapeutics, Inc.

Ticker FULC
Exchange NASDAQ
Sector Healthcare
Industry Biotechnology
Shares Outstandng 52,038,900
Market Cap $451M
Description
Fulcrum Therapeutics, Inc., a clinical-stage biopharmaceutical company, focuses on developing products for improving the lives of patients with genetically defined diseases in the areas of high unmet medical need in the United States. Its product candidates are losmapimod, a small molecule for the treatment of facioscapulohumeral muscular dystro...

More about FULC

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