Diadema Partners LP Options Holdings

Diadema Partners LP

  • $391 Billion
  • Q3 2025

Options Holdings Table

Stock Option Type Value Options Held Last Trade Trade History
QURE
Uni Qure N.V.

Healthcare
PUT
$17.5 Billion
300K
Q3 2025
New holding
SPY
Spdr S&P 500 ETF Trust

ETFs
PUT
$13.3 Billion
20K
Q3 2025
New holding
JAZZ
Jazz Pharmaceuticals PLC

Healthcare
CALL
$13.2 Billion
100K
Q3 2025
New holding
VKTX
Viking Therapeutics, Inc.

Healthcare
CALL
$10.6 Billion
405K
Q3 2025
New holding
AGIO
Agios Pharmaceuticals, Inc.

Healthcare
CALL
$8.92 Billion
222K
Q3 2025
Added 81.9%
RNA
Avidity Biosciences, Inc.

Healthcare
CALL
$8.72 Billion
200K
Q3 2025
New holding
INCY
Incyte Corp

Healthcare
CALL
$8.48 Billion
100K
Q3 2025
New holding
NTLA
Intellia Therapeutics, Inc.

Healthcare
CALL
$8.12 Billion
470K
Q3 2025
New holding
BMY
Bristol Myers Squibb CO

Healthcare
CALL
$8.12 Billion
180K
Q3 2025
New holding
LLY
Eli Lilly & CO

Healthcare
PUT
$7.63 Billion
10K
Q3 2025
Reduced 51.69%
BBIO
Bridge Bio Pharma, Inc.

Healthcare
CALL
$6.82 Billion
131K
Q1 2025
Added 31.4%
Soleno Therapeutics Inc
PUT
$6.76 Billion
100K
Q3 2025
New holding
JAZZ
Jazz Pharmaceuticals PLC

Healthcare
PUT
$6.59 Billion
50K
Q3 2025
New holding
IONS
Ionis Pharmaceuticals Inc

Healthcare
CALL
$6.54 Billion
100K
Q3 2025
New holding
MNKD
Mannkind Corp

Healthcare
CALL
$5.58 Billion
1.04M
Q3 2025
Added 99.94%
NVO
Novo Nordisk A S

Healthcare
PUT
$5.55 Billion
100K
Q3 2025
New holding
Praxis Precision Medicines I
PUT
$5.3 Billion
100K
Q3 2025
New holding
Apogee Therapeutics Inc
CALL
$5.06 Billion
127K
Q3 2025
Reduced 18.49%
ROIV
Roivant Sciences Ltd.

Healthcare
PUT
$4.54 Billion
300K
Q3 2025
New holding
RARE
Ultragenyx Pharmaceutical Inc.

Healthcare
CALL
$4.51 Billion
150K
Q3 2025
Reduced 30.88%
HRMY
Harmony Biosciences Holdings, Inc.

Healthcare
CALL
$4.13 Billion
150K
Q3 2025
New holding
Upstream Bio Inc
CALL
$3.76 Billion
200K
Q3 2025
New holding
SRRK
Scholar Rock Holding Corp

Healthcare
CALL
$3.72 Billion
100K
Q3 2025
New holding
RARE
Ultragenyx Pharmaceutical Inc.

Healthcare
PUT
$3.71 Billion
123K
Q3 2025
Reduced 30.88%
RXRX
Recursion Pharmaceuticals, Inc.

Healthcare
CALL
$3.41 Billion
698K
Q1 2025
Added 132.8%
Zymeworks Inc
CALL
$3.36 Billion
197K
Q3 2025
Added 9.59%
Soleno Therapeutics Inc
CALL
$3.38 Billion
50K
Q3 2025
New holding
MREO
Mereo Biopharma Group PLC

Healthcare
CALL
$3.13 Billion
1.52M
Q3 2025
Added 15.38%
COGT
Cogent Biosciences, Inc.

Healthcare
CALL
$2.87 Billion
200K
Q3 2025
Added 2798.55%
ARCT
Arcturus Therapeutics Holdings Inc.

Healthcare
PUT
$2.78 Billion
151K
Q3 2025
New holding
MRNA
Moderna, Inc.

Healthcare
CALL
$2.64 Billion
102K
Q2 2025
Added 95.97%
SCPH
Sc Pharmaceuticals Inc.

Healthcare
CALL
$2.62 Billion
462K
Q3 2025
Reduced 5.04%
REPL
Replimune Group, Inc.

Healthcare
CALL
$2.57 Billion
612K
Q3 2025
New holding
MRNA
Moderna, Inc.

Healthcare
PUT
$2.58 Billion
100K
Q2 2025
Added 95.97%
ABUS
Arbutus Biopharma Corp

Healthcare
CALL
$2.34 Billion
516K
Q3 2025
New holding
CORT
Corcept Therapeutics Inc

Healthcare
PUT
$2.2 Billion
26.5K
Q3 2025
Reduced 73.55%
CAPR
Capricor Therapeutics, Inc.

Healthcare
CALL
$2.16 Billion
300K
Q3 2025
New holding
GOSS
Gossamer Bio, Inc.

Healthcare
CALL
$2.17 Billion
825K
Q1 2025
Added 221.06%
ACAD
Acadia Pharmaceuticals Inc

Healthcare
CALL
$1.9 Billion
89K
Q3 2025
Added 0.11%
Mbx Biosciences Inc
CALL
$1.75 Billion
100K
Q3 2025
New holding
ALT
Altimmune, Inc.

Healthcare
CALL
$1.75 Billion
463K
Q3 2025
Reduced 63.34%
TERN
Terns Pharmaceuticals, Inc.

Healthcare
CALL
$1.69 Billion
225K
Q3 2025
Added 39.96%
OCUL
Ocular Therapeutix, Inc

Healthcare
CALL
$1.6 Billion
137K
Q1 2025
Added 31.44%
Tectonic Therapeutic Inc
CALL
$1.57 Billion
100K
Q3 2025
New holding
SMMT
Summit Therapeutics Inc.

Healthcare
CALL
$1.54 Billion
74.7K
Q2 2025
New holding
NVAX
Novavax Inc

Healthcare
CALL
$1.5 Billion
174K
Q3 2025
New holding
HRMY
Harmony Biosciences Holdings, Inc.

Healthcare
PUT
$1.38 Billion
50.1K
Q3 2025
New holding
AVXL
Anavex Life Sciences Corp.

Healthcare
CALL
$1.24 Billion
140K
Q3 2025
New holding
CRMD
Cor Medix Inc.

Healthcare
PUT
$1.16 Billion
100K
Q3 2025
New holding

Summary

  • Portfolio
  • No. of Stocks 130
  • Current Value $391 Billion
  • Prior Value $328 Billion
  • Filing
  • Period Q3 2025
  • Filing Date November 14, 2025
  • Form Type 13F-HR
  • Activity in Q3 2025
  • New Purchases 33 stocks
  • Additional Purchases 6 stocks
  • Sold out of 0 stocks
  • Reduced holdings in 16 stocks
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