Paradigm Biocapital Advisors LP Portfolio Holdings

Paradigm Biocapital Advisors LP

  • $3.1 Billion
  • Q3 2025

Paradigm Biocapital Advisors LP has filed its 13F form on November 14, 2025 for Q3 2025 where it was disclosed a total value porftolio of $3.1 Billion distributed in 36 stocks.

Among their holdings, we can observe that their the top five positions include companies like: Nuvalent, Inc. with a value of $456M, Merus N.V. with a value of $412M, Arcellx, Inc. with a value of $382M, Revolution Medicines, Inc. with a value of $291M, and Tarsus Pharmaceuticals, Inc. with a value of $158M.

Examining the 13F form we can see an increase of $962M in the current position value, from $2.14B to 3.1B.

Paradigm Biocapital Advisors LP is based out at New York, NY

Below you can find more details about Paradigm Biocapital Advisors LP portfolio as well as his latest detailed transactions.

Portfolio value $3.1 Billion
Healthcare: $3 Billion
ETFs: $100 Million

Stock Holdings Table Market Cap. of $300 Millions to $2 Billions

Stock Market Cap. Holding Value (Reported) # of Shares. Last Trade Trade History
$1.92B
$158 Million 5.1% of portfolio
2,665,698
Q3 2025 Reduced 10.43%
$1.44B
$100 Million 3.22% of portfolio
6,170,131
Q3 2025 Added 0.45%
$553M
$82.3 Million 2.65% of portfolio
4,216,084
Q3 2025 New
$1.95B
$75.1 Million 2.42% of portfolio
2,009,745
Q3 2025 Added 25.57%
$1.22B
$71.4 Million 2.3% of portfolio
2,920,258
Q2 2025 Reduced 12.3%
$351M
$65.6 Million 2.11% of portfolio
6,794,172
Q3 2025 Added 0.44%
$1.15B
$56.1 Million 1.81% of portfolio
2,609,353
Q3 2025 Reduced 4.82%
$795M
$45.8 Million 1.48% of portfolio
1,835,494
Q3 2025 Added 72.69%
$875M
$40.9 Million 1.32% of portfolio
3,497,307
Q3 2025 Added 2.25%
$315M
$29.6 Million 0.95% of portfolio
13,560,017
Q3 2025 Added 13.88%
$404M
$27.8 Million 0.89% of portfolio
2,005,365
Q3 2025 New
$720M
$25.9 Million 0.84% of portfolio
3,086,184
Q3 2025 New
$743M
$25.8 Million 0.83% of portfolio
1,900,000
Q3 2025 New
$975M
$24 Million 0.77% of portfolio
1,898,950
Q3 2025 New

Summary

  • Portfolio
  • No. of Stocks 36
  • Current Value $3.1 Billion
  • Prior Value $2.14 Billion
  • Filing
  • Period Q3 2025
  • Filing Date November 14, 2025
  • Form Type 13F-HR
  • Activity in Q3 2025
  • New Purchases 10 stocks
  • Additional Purchases 13 stocks
  • Sold out of 0 stocks
  • Reduced holdings in 7 stocks
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