Two Sigma Investments, LP Astrazeneca PLC Transaction History

Two Sigma Investments, LP

$59 Billion
Q3 2025

A detailed history of Two Sigma Investments, LP transactions in Astrazeneca PLC stock. As of the latest transaction made, Two Sigma Investments, LP holds 517,695 shares of AZN stock, worth $46.3 Million. This represents 0.07% of its overall portfolio holdings.

Number of Shares

517,695

Previous 858,505 39.7%

Holding current value

$46.3 Million

Previous $60 Million 33.8%

% of portfolio

0.07%

Previous 0.12%

30 transactions

Quarter	Operation	Price Per share	shares change	shares Held
Q3 2025 Nov 14, 2025	SELL	$68.72 - $82.11 $23.4 Million - $28 Million	-340,810 Reduced 39.7%	517,695 $39.7 Million
Q2 2025 Aug 14, 2025	BUY	$64.87 - $75.0 $26.2 Million - $30.3 Million	403,965 Added 88.87%	858,505 $60 Million
Q1 2025 May 15, 2025	SELL	$65.37 - $77.96 $13.5 Million - $16.1 Million	-207,130 Reduced 31.3%	454,540 $33.4 Million
Q4 2024 Feb 14, 2025	SELL	$63.2 - $79.58 $27.7 Million - $34.8 Million	-437,786 Reduced 39.82%	661,670 $43.4 Million
Q3 2024 Nov 14, 2024	SELL	$76.67 - $87.62 $91.2 Million - $104 Million	-1,189,033 Reduced 51.96%	1,099,456 $85.7 Million

Q2 2024 Aug 14, 2024	SELL	$66.81 - $80.83 $60.2 Million - $72.8 Million	-900,866 Reduced 28.25%	2,288,489 $178 Million
Q1 2024 May 15, 2024	BUY	$61.03 - $69.57 $51 Million - $58.1 Million	834,839 Added 35.46%	3,189,355 $216 Million
Q4 2023 Feb 14, 2024	BUY	$61.89 - $69.28 $68.6 Million - $76.8 Million	1,109,144 Added 89.06%	2,354,516 $159 Million
Q3 2023 Nov 14, 2023	BUY	$64.85 - $71.7 $74.6 Million - $82.4 Million	1,149,748 Added 1202.36%	1,245,372 $84.3 Million
Q2 2023 Aug 14, 2023	BUY	$69.91 - $75.81 $4.85 Million - $5.26 Million	69,445 Added 265.27%	95,624 $6.84 Million
Q1 2023 May 15, 2023	SELL	$63.15 - $71.6 $103 Million - $117 Million	-1,627,485 Reduced 98.42%	26,179 $1.82 Million
Q4 2022 Feb 14, 2023	BUY	$54.21 - $70.44 $46.8 Million - $60.8 Million	863,841 Added 109.37%	1,653,664 $112 Million
Q3 2022 Nov 14, 2022	BUY	$53.02 - $135.75 $35.5 Million - $90.9 Million	669,345 Added 555.57%	789,823 $43.3 Million
Q2 2022 Aug 15, 2022	SELL	$59.26 - $71.14 $14.4 Million - $17.3 Million	-243,433 Reduced 66.89%	120,478 $7.96 Million
Q1 2022 May 16, 2022	SELL	$55.72 - $67.12 $28.8 Million - $34.7 Million	-516,594 Reduced 58.67%	363,911 $24.1 Million
Q4 2021 Feb 14, 2022	BUY	$54.02 - $63.83 $31.2 Million - $36.9 Million	577,756 Added 190.84%	880,505 $51.3 Million
Q3 2021 Nov 15, 2021	SELL	$55.56 - $60.79 $27.9 Million - $30.5 Million	-502,023 Reduced 62.38%	302,749 $18.2 Million
Q2 2021 Aug 16, 2021	BUY	$48.42 - $60.18 $35.1 Million - $43.6 Million	724,348 Added 900.66%	804,772 $48.2 Million
Q1 2021 May 17, 2021	BUY	$47.16 - $54.44 $3.79 Million - $4.38 Million	80,424 New	80,424 $4 Million
Q3 2020 Nov 16, 2020	SELL	$53.07 - $61.1 $30.4 Million - $35.1 Million	-573,741 Closed	0 $0
Q2 2020 Aug 14, 2020	BUY	$43.1 - $55.31 $20.8 Million - $26.7 Million	482,488 Added 528.74%	573,741 $30.3 Million
Q1 2020 May 15, 2020	BUY	$37.79 - $51.33 $493,121 - $669,805	13,049 Added 16.69%	91,253 $4.08 Million
Q4 2019 Feb 14, 2020	BUY	$42.46 - $50.46 $3.32 Million - $3.95 Million	78,204 New	78,204 $3.9 Million
Q3 2019 Nov 14, 2019	SELL	$40.12 - $45.47 $26.6 Million - $30.1 Million	-662,093 Closed	0 $0
Q2 2019 Aug 14, 2019	BUY	$37.28 - $41.68 $24.7 Million - $27.6 Million	662,093 New	662,093 $27.3 Million
Q4 2018 Feb 14, 2019	SELL	$36.86 - $41.49 $207,300 - $233,339	-5,624 Closed	0 $0
Q3 2018 Nov 14, 2018	SELL	$34.76 - $39.72 $4.22 Million - $4.83 Million	-121,527 Reduced 95.58%	5,624 $223,000
Q2 2018 Aug 14, 2018	SELL	$34.55 - $37.05 $46.9 Million - $50.3 Million	-1,357,222 Reduced 91.43%	127,151 $4.46 Million
Q1 2018 May 15, 2018	BUY	$32.97 - $36.63 $19.7 Million - $21.9 Million	597,682 Added 67.41%	1,484,373 $51.9 Million
Q4 2017 Feb 14, 2018	BUY	$32.09 - $34.78 $28.5 Million - $30.8 Million	886,691	886,691 $30.8 Million

Others Institutions Holding AZN

# of Institutions

1,498

Shares Held

500M

Call Options Held

5.59M

Put Options Held

3.18M

View Full List

About ASTRAZENECA PLC

Ticker AZN
Exchange OTC
Sector Healthcare
Industry Drug Manufacturers—General
Shares Outstandng 3,099,020,032
Market Cap $277B
Description
AstraZeneca PLC, a biopharmaceutical company, focuses on the discovery, development, manufacturing, and commercialization of prescription medicines. Its marketed products include Calquence, Enhertu, Faslodex, Imfinzi, Iressa, Koselugo, Lumoxiti, Lynparza, Orpathys, Tagrisso, and Zoladex for oncology; Brilinta/Brilique, Bydureon/Byetta, BCise, By...

More about AZN

Track This Portfolio

Portfolio Update

Get notified when there are updates to the investment portfolio of Two Sigma Investments, LP, based on Form 13F filings with the SEC.

News

Stay updated on Two Sigma Investments, LP with notifications on news.

Account

Two Sigma Investments, LP Astrazeneca PLC Transaction History