Two Sigma Investments, LP Pliant Therapeutics, Inc. Transaction History

Two Sigma Investments, LP

$59 Billion
Q3 2025

A detailed history of Two Sigma Investments, LP transactions in Pliant Therapeutics, Inc. stock. As of the latest transaction made, Two Sigma Investments, LP holds 783,255 shares of PLRX stock, worth $1.36 Million. This represents 0.0% of its overall portfolio holdings.

Number of Shares

783,255

Previous 278,158 181.59%

Holding current value

$1.36 Million

Previous $322,000 259.94%

% of portfolio

0.0%

Previous 0.0%

15 transactions

Quarter	Operation	Price Per share	shares change	shares Held
Q3 2025 Nov 14, 2025	BUY	$1.18 - $1.86 $596,014 - $939,480	505,097 Added 181.59%	783,255 $1.16 Million
Q2 2025 Aug 14, 2025	BUY	$1.16 - $1.69 $3,330 - $4,851	2,871 Added 1.04%	278,158 $322,000
Q1 2025 May 15, 2025	BUY	$1.35 - $13.53 $240,582 - $2.41 Million	178,209 Added 183.57%	275,287 $371,000
Q4 2024 Feb 14, 2025	SELL	$10.55 - $15.7 $401,364 - $597,290	-38,044 Reduced 28.16%	97,078 $1.28 Million
Q3 2024 Nov 14, 2024	SELL	$10.52 - $14.35 $1.16 Million - $1.58 Million	-110,450 Reduced 44.98%	135,122 $1.51 Million

Q2 2024 Aug 14, 2024	BUY	$10.58 - $15.61 $1.47 Million - $2.16 Million	138,548 Added 129.46%	245,572 $2.64 Million
Q1 2024 May 15, 2024	BUY	$14.14 - $19.59 $1.51 Million - $2.1 Million	107,024 New	107,024 $1.59 Million
Q3 2023 Nov 14, 2023	SELL	$14.58 - $20.15 $3.16 Million - $4.36 Million	-216,577 Reduced 67.83%	102,709 $1.78 Million
Q2 2023 Aug 14, 2023	SELL	$18.12 - $30.56 $1.76 Million - $2.98 Million	-97,364 Reduced 23.37%	319,286 $5.79 Million
Q1 2023 May 15, 2023	BUY	$18.73 - $36.26 $3.73 Million - $7.22 Million	199,205 Added 91.61%	416,650 $11.1 Million
Q4 2022 Feb 14, 2023	SELL	$17.0 - $25.43 $519,554 - $777,191	-30,562 Reduced 12.32%	217,445 $4.2 Million
Q3 2022 Nov 14, 2022	BUY	$7.67 - $24.23 $1.79 Million - $5.67 Million	234,007 Added 1671.48%	248,007 $5.18 Million
Q2 2022 Aug 15, 2022	SELL	$4.11 - $8.75 $457,352 - $973,682	-111,278 Reduced 88.82%	14,000 $112,000
Q1 2022 May 16, 2022	BUY	$7.01 - $14.1 $65,256 - $131,256	9,309 Added 8.03%	125,278 $878,000
Q4 2021 Feb 14, 2022	BUY	$12.27 - $18.26 $1.42 Million - $2.12 Million	115,969 New	115,969 $1.57 Million

Others Institutions Holding PLRX

# of Institutions

113

Shares Held

58.9M

Call Options Held

209K

Put Options Held

102K

View Full List

About PLIANT THERAPEUTICS, INC.

Ticker PLRX
Exchange NASDAQ
Sector Healthcare
Industry Biotechnology
Shares Outstandng 48,682,000
Market Cap $84.2M
Description
Pliant Therapeutics, Inc., a clinical stage biopharmaceutical company, discovers, develops, and commercializes novel therapies for the treatment of fibrosis and related diseases in the United States. Its lead product candidate is PLN-74809, an oral small-molecule dual selective inhibitor of avß6 and avß1 integrins, which is in three Phase 2a tri...

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Two Sigma Investments, LP Pliant Therapeutics, Inc. Transaction History