The Securities and Exchange Commission has not necessarily reviewed the information in this filing and has not determined if it is accurate and complete.
The reader should not assume that the information is accurate and complete.

UNITED STATES SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549
FORM 13F

FORM 13F INFORMATION TABLE
OMB APPROVAL
OMB Number: 3235-0006
Estimated average burden
hours per response: 23.8
COLUMN 1 COLUMN 2 COLUMN 3 COLUMN 4 COLUMN 5 COLUMN 6 COLUMN 7 COLUMN 8
VALUE SHRS OR SH/ PUT/ INVESTMENT OTHER VOTING AUTHORITY
NAME OF ISSUER TITLE OF CLASS CUSIP (x$1000) PRN AMT PRN CALL DISCRETION MANAGER SOLE SHARED NONE
ACADIA PHARMACEUTICALS INC COM 004225108 10,047 333,773 SH   SOLE   333,773 0 0
ACHAOGEN INC COM 004449104 2,197 204,538 SH   SOLE   204,538 0 0
ADAMAS PHARMACEUTICALS INC COM 00548A106 10,669 315,000 SH   SOLE   315,000 0 0
AERIE PHARMACEUTICALS INC COM 00771V108 883 14,779 SH   SOLE   14,779 0 0
AGIOS PHARMACEUTICALS INC COM 00847X104 1,143 20,000 SH   SOLE   20,000 0 0
ALEXION PHARMACEUTICALS INC COM 015351109 8,665 72,441 SH   SOLE   72,441 0 0
ALNYLAM PHARMACEUTICALS INC COM 02043Q107 4,675 36,800 SH   SOLE   36,800 0 0
AMGEN INC COM 031162100 6,279 36,104 SH   SOLE   36,104 0 0
AMICUS THERAPEUTICS INC COM 03152W109 843 58,600 SH   SOLE   58,600 0 0
ANAPTYSBIO INC COM 032724106 1,711 17,000 SH   SOLE   17,000 0 0
ARRAY BIOPHARMA INC COM 04269X105 6,112 477,500 SH   SOLE   477,500 0 0
AVEXIS INC COM 05366U100 1,881 17,000 SH   SOLE   17,000 0 0
BEIGENE LTD SPONSORED ADR 07725L102 928 9,500 SH   SOLE   9,500 0 0
BIOGEN INC COM 09062X103 20,710 65,008 SH   SOLE   65,008 0 0
BIOMARIN PHARMACEUTICAL INC COM 09061G101 6,097 68,384 SH   SOLE   68,384 0 0
BLUEBIRD BIO INC COM 09609G100 3,560 20,000 SH   SOLE   20,000 0 0
CELGENE CORP COM 151020104 19,833 190,022 SH   SOLE   190,022 0 0
CLOVIS ONCOLOGY INC COM 189464100 5,168 76,000 SH   SOLE   76,000 0 0
CYMABAY THERAPEUTICS INC COM 23257D103 1,334 145,000 SH   SOLE   145,000 0 0
DECIPHERA PHARMACEUTICALS INC COM 24344T101 1,746 77,000 SH   SOLE   77,000 0 0
DERMIRA INC COM 24983L104 3,004 108,000 SH   SOLE   108,000 0 0
EXELIXIS INC COM 30161Q104 12,470 410,334 SH   SOLE   410,334 0 0
FIBROGEN INC COM 31572Q808 1,488 31,400 SH   SOLE   31,400 0 0
FIVE PRIME THERAPEUTICS INC COM 33830X104 2,531 115,500 SH   SOLE   115,500 0 0
FOAMIX PHARMACEUTICALS LTD SHS M46135105 2,301 382,838 SH   SOLE   382,838 0 0
G1 THERAPEUTICS INC COM 3621LQ109 773 39,000 SH   SOLE   39,000 0 0
GILEAD SCIENCES INC COM 375558103 8,798 122,784 SH   SOLE   122,784 0 0
GW PHARMACEUTICALS PLC ADS 36197T103 1,267 9,600 SH   SOLE   9,600 0 0
HALOZYME THERAPEUTICS INC COM 40637H109 5,723 282,633 SH   SOLE   282,633 0 0
HORIZON PHARMA PLC SHS G4617B105 1,007 69,000 SH   SOLE   69,000 0 0
INCYTE CORP COM 45337C102 6,912 72,975 SH   SOLE   72,975 0 0
IONIS PHARMACEUTICALS INC COM 462222100 2,589 51,500 SH   SOLE   51,500 0 0
JUNO THERAPEUTICS INC COM 48205A109 2,284 50,000 SH   SOLE   50,000 0 0
LIGAND PHARMACEUTICALS INC COM 53220K504 3,971 29,000 SH   SOLE   29,000 0 0
MADRIGAL PHARMACEUTICALS INC COM 558868105 2,293 25,000 SH   SOLE   25,000 0 0
MERUS NV COM NS749R100 1,413 75,060 SH   SOLE   75,060 0 0
MOLECULAR TEMPLATES INC COM 608550109 2,476 247,587 SH   SOLE   247,587 0 0
NEKTAR THERAPEUTICS COM 640268108 12,597 211,000 SH   SOLE   211,000 0 0
NEUROCRINE BIOSCIENCES INC COM 64125C109 2,871 37,000 SH   SOLE   37,000 0 0
OMEROS CORP COM 682143102 660 34,000 SH   SOLE   34,000 0 0
OPTINOSE INC COM 68404V100 1,228 65,000 SH   SOLE   65,000 0 0
PARATEK PHARMACEUTICALS INC COM 699374302 4,538 253,500 SH   SOLE   253,500 0 0
PORTOLA PHARMACEUTICALS INC COM 737010108 1,168 24,000 SH   SOLE   24,000 0 0
PROTHENA CORP PLC SHS G72800108 562 15,000 SH   SOLE   15,000 0 0
PUMA BIOTECHNOLOGY INC COM 74587V107 1,186 12,000 SH   SOLE   12,000 0 0
RADIUS HEALTH INC COM 750469207 597 18,799 SH   SOLE   18,799 0 0
REGENERON PHARMACEUTICALS COM 75886F107 15,354 40,830 SH   SOLE   40,830 0 0
SAGE THERAPEUTICS INC COM 78667J108 8,481 51,496 SH   SOLE   51,496 0 0
SANGAMO THERAPEUTICS INC COM 800677106 3,034 185,000 SH   SOLE   185,000 0 0
SAREPTA THERAPEUTICS INC COM 803607100 1,502 27,000 SH   SOLE   27,000 0 0
SEATTLE GENETICS INC COM 812578102 3,077 57,500 SH   SOLE   57,500 0 0
SHIRE PLC SPONSORED ADR 82481R106 4,839 31,200 SH   SOLE   31,200 0 0
SPARK THERAPEUTICS INC COM 84652J103 617 12,000 SH   SOLE   12,000 0 0
SPRING BR PHARMACEUTICALS INC COM 849431101 956 73,000 SH   SOLE   73,000 0 0
STEMLINE THERAPEUTICS INC COM 85858C107 7,690 492,930 SH   SOLE   492,930 0 0
SUPERNUS PHARMACEUTICALS INC COM 868459108 834 20,953 SH   SOLE   20,953 0 0
SYNERGY PHARMACEUTICALS COM 871639308 3,358 1,505,804 SH   SOLE   1,505,804 0 0
TESARO INC COM 881569107 6,406 77,300 SH   SOLE   77,300 0 0
VERTEX PHARMACEUTICALS INC COM 92532F100 11,304 75,422 SH   SOLE   75,422 0 0
VIKING THERAPEUTICS INC COM 92686J106 284 70,000 SH   SOLE   70,000 0 0
XENCOR INC COM 98401F105 395 18,000 SH   SOLE   18,000 0 0
ENTELLUS MED INC COM 29363K105 8,325 341,468 SH   SOLE   341,468 0 0
RESHAPE LIFESCIENCES INC COM 761123108 1,151 788,194 SH   SOLE   788,194 0 0
TRANSENTERIX INC COM 89366M201 1,707 889,082 SH   SOLE   889,082 0 0
KALVISTA PHARMACEUTICALS INC COM 483497103 3,137 322,436 SH   SOLE   322,436 0 0