The Securities and Exchange Commission has not necessarily reviewed the information in this filing and has not determined if it is accurate and complete.
The reader should not assume that the information is accurate and complete.

UNITED STATES SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549
FORM 13F

FORM 13F INFORMATION TABLE
OMB APPROVAL
OMB Number: 3235-0006
Estimated average burden
hours per response: 23.8
COLUMN 1 COLUMN 2 COLUMN 3 COLUMN 4 COLUMN 5 COLUMN 6 COLUMN 7 COLUMN 8
VALUE SHRS OR SH/ PUT/ INVESTMENT OTHER VOTING AUTHORITY
NAME OF ISSUER TITLE OF CLASS CUSIP FIGI (to the nearest dollar) PRN AMT PRN CALL DISCRETION MANAGER SOLE SHARED NONE
AADI BIOSCIENCE INC COM 00032Q104   1,051,331 333,227 SH   SOLE   333,227 0 0
ABIVAX SA SPONSORED ADS 00370M103   915,000 125,000 SH   SOLE   125,000 0 0
ADAPTIVE BIOTECHNOLOGIES COR COM 00650F109   17,883,936 2,983,142 SH   SOLE   2,983,142 0 0
ADVERUM BIOTECHNOLOGIES INC COM NEW 00773U207   1,341,439 287,246 SH   SOLE   287,246 0 0
ALNYLAM PHARMACEUTICALS INC COM 02043Q107   18,071,808 76,800 SH   SOLE   76,800 0 0
ANAPTYSBIO INC COM 032724106   5,481,360 414,000 SH   SOLE   414,000 0 0
ANI PHARMACEUTICALS INC COM 00182C103   11,348,652 205,294 SH   SOLE   205,294 0 0
APOGEE THERAPEUTICS INC COM 03770N101   3,171,000 70,000 SH   SOLE   70,000 0 0
ARCELLX INC COMMON STOCK 03940C100   9,281,867 121,031 SH   SOLE   121,031 0 0
ASCENDIS PHARMA A/S SPONSORED ADR 04351P101   19,824,480 144,000 SH   SOLE   144,000 0 0
ASTRAZENECA PLC SPONSORED ADR 046353108   26,797,680 409,000 SH   SOLE   409,000 0 0
AXOGEN INC COM 05463X106   48,713,941 2,955,943 SH   SOLE   2,955,943 0 0
BAUSCH PLUS LOMB CORP COMMON SHARES 071705107   2,176,230 120,500 SH   SOLE   120,500 0 0
BEIGENE LTD SPONSORED ADR 07725L102   212,417 1,150 SH   SOLE   1,150 0 0
BIOMARIN PHARMACEUTICAL INC COM 09061G101   65,822,022 1,001,400 SH   SOLE   1,001,400 0 0
C4 THERAPEUTICS INC COM STK 12529R107   25,124,191 6,978,942 SH   SOLE   6,978,942 0 0
CALCIMEDICA INC COM NEW 38942Q202   2,775,020 783,904 SH   SOLE   783,904 0 0
CASTLE BIOSCIENCES INC COM 14843C105   6,740,238 252,917 SH   SOLE   252,917 0 0
CELCUITY INC COM 15102K100   33,576,989 2,565,087 SH   SOLE   2,565,087 0 0
CG ONCOLOGY INC COM 156944100   9,423,818 328,585 SH   SOLE   328,585 0 0
CRINETICS PHARMACEUTICALS IN COM 22663K107   4,346,050 85,000 SH   SOLE   85,000 0 0
DELCATH SYS INC COM NEW 24661P807   9,644,040 801,000 SH   SOLE   801,000 0 0
EDAP TMS S A SPONSORED ADR 268311107   16,153,451 7,309,254 SH   SOLE   7,309,254 0 0
EDGEWISE THERAPEUTICS INC COM 28036F105   4,894,110 183,300 SH   SOLE   183,300 0 0
ELEVANCE HEALTH INC COM 036752103   202,895 550 SH   SOLE   550 0 0
ELI LILLY & CO COM 532457108   8,999,976 11,658 SH   SOLE   11,658 0 0
ENLIVEN THERAPEUTICS INC COM 29337E102   1,696,613 75,405 SH   SOLE   75,405 0 0
ERASCA INC COM 29479A108   5,427,027 2,162,162 SH   SOLE   2,162,162 0 0
ESSA PHARMA INC COM NEW 29668H708   4,049,027 2,262,026 SH   SOLE   2,262,026 0 0
ESTABLISHMENT LABS HLDGS INC COM G31249108   2,736,558 59,400 SH   SOLE   59,400 0 0
EVOLUS INC COM 30052C107   7,696,624 697,158 SH   SOLE   697,158 0 0
GENEDX HOLDINGS CORP COM CL A 81663L200   307,440 4,000 SH   SOLE   4,000 0 0
GRIFOLS S A SP ADR REP B NVT 398438408   49,144,362 6,605,425 SH   SOLE   6,605,425 0 0
GSK PLC SPONSORED ADR 37733W204   341,920 10,110 SH   SOLE   10,110 0 0
IMMUNIC INC COM 4525EP101   7,293,007 7,293,007 SH   SOLE   7,293,007 0 0
INHIBIKASE THERAPEUTICS INC COM NEW 45719W205   20,556,250 6,325,000 SH   SOLE   6,325,000 0 0
INSMED INC COM PAR $.01 457669307   22,111,579 320,272 SH   SOLE   320,272 0 0
INSPIREMD INC COM 45779A846   3,624,477 1,378,128 SH   SOLE   1,378,128 0 0
INTEGRA LIFESCIENCES HLDGS C COM NEW 457985208   28,939,680 1,276,000 SH   SOLE   1,276,000 0 0
IO BIOTECH INC COM 449778109   177,256 192,670 SH   SOLE   192,670 0 0
IOVANCE BIOTHERAPEUTICS INC COM 462260100   48,544,000 6,560,000 SH   SOLE   6,560,000 0 0
JASPER THERAPEUTICS INC COM NEW 471871202   31,950,700 1,494,420 SH   SOLE   1,494,420 0 0
KRYSTAL BIOTECH INC COM 501147102   56,143,654 358,379 SH   SOLE   358,379 0 0
MADRIGAL PHARMACEUTICALS INC COM 558868105   3,363,413 10,900 SH   SOLE   10,900 0 0
MDXHEALTH SA SHS NEW B5950S113   2,018,501 851,688 SH   SOLE   851,688 0 0
MEREO BIOPHARMA GROUP PLC SPON ADS 589492107   2,754,336 786,953 SH   SOLE   786,953 0 0
MERUS N V COM N5749R100   13,133,098 312,321 SH   SOLE   312,321 0 0
MYOMO INC COM NEW 62857J201   5,796,000 900,000 SH   SOLE   900,000 0 0
NEUROPACE INC COM 641288105   27,227,150 2,433,168 SH   SOLE   2,433,168 0 0
NOVOCURE LTD ORD SHS G6674U108   81,643,179 2,739,704 SH   SOLE   2,739,704 0 0
NURIX THERAPEUTICS INC COM 67080M103   39,617,374 2,102,833 SH   SOLE   2,102,833 0 0
NUVALENT INC COM 670703107   8,169,066 104,357 SH   SOLE   104,357 0 0
ORGANOGENESIS HLDGS INC COM 68621F102   39,951,603 12,484,876 SH   SOLE   12,484,876 0 0
ORTHOFIX MED INC COM 68752M108   11,984,090 686,374 SH   SOLE   686,374 0 0
PHARVARIS N V COM N69605108   15,616,879 814,652 SH   SOLE   814,652 0 0
PRAXIS PRECISION MEDICINES I COM NEW 74006W207   18,742,838 243,540 SH   SOLE   243,540 0 0
PROTAGONIST THERAPEUTICS INC COM 74366E102   10,615,000 275,000 SH   SOLE   275,000 0 0
QUIDELORTHO CORP COM 219798105   24,372,503 547,082 SH   SOLE   547,082 0 0
REGENERON PHARMACEUTICALS COM 75886F107   1,638,359 2,300 SH   SOLE   2,300 0 0
REPLIMUNE GROUP INC COM 76029N106   3,178,875 262,500 SH   SOLE   262,500 0 0
REVOLUTION MEDICINES INC COM 76155X100   8,795,414 201,084 SH   SOLE   201,084 0 0
RIGEL PHARMACEUTICALS INC COM 766559702   19,018,021 1,130,679 SH   SOLE   1,130,679 0 0
ROCKET PHARMACEUTICALS INC COM 77313F106   3,414,754 271,659 SH   SOLE   271,659 0 0
SCHOLAR ROCK HLDG CORP COM 80706P103   7,241,208 167,543 SH   SOLE   167,543 0 0
SEPTERNA INC COM 81734D104   15,466,866 675,409 SH   SOLE   675,409 0 0
SPDR SER TR S&P BIOTECH 78464A870   270,180,000 3,000,000 SH Call SOLE   3,000,000 0 0
SURMODICS INC COM 868873100   15,604,776 394,060 SH   SOLE   394,060 0 0
SYNDAX PHARMACEUTICALS INC COM 87164F105   32,944,240 2,492,000 SH   SOLE   2,492,000 0 0
TAKEDA PHARMACEUTICAL CO LTD SPONSORED ADS 874060205   15,623,200 1,180,000 SH   SOLE   1,180,000 0 0
TECTONIC THERAPEUTIC INC COM 878972108   1,470,099 31,841 SH   SOLE   31,841 0 0
TENET HEALTHCARE CORP COM NEW 88033G407   255,868 2,027 SH   SOLE   2,027 0 0
TERNS PHARMACEUTICALS INC COM 880881107   45,109,450 8,142,500 SH   SOLE   8,142,500 0 0
TEVA PHARMACEUTICAL INDS LTD SPONSORED ADS 881624209   46,129,720 2,093,000 SH   SOLE   2,093,000 0 0
TG THERAPEUTICS INC COM 88322Q108   80,705,384 2,681,242 SH   SOLE   2,681,242 0 0
THERATECHNOLOGIES INC COM NEW 88338H704   8,690,491 4,801,376 SH   SOLE   4,801,376 0 0
UNITED THERAPEUTICS CORP DEL COM 91307C102   38,598,579 109,394 SH   SOLE   109,394 0 0
VAXCYTE INC COM 92243G108   8,108,233 99,050 SH   SOLE   99,050 0 0
VERASTEM INC COM NEW 92337C203   11,291,414 2,184,026 SH   SOLE   2,184,026 0 0
VERICEL CORP COM 92346J108   4,431,017 80,696 SH   SOLE   80,696 0 0
VIRIDIAN THERAPEUTICS INC COM 92790C104   872,235 45,500 SH   SOLE   45,500 0 0
Y-MABS THERAPEUTICS INC COM 984241109   2,740,359 349,982 SH   SOLE   349,982 0 0