The Securities and Exchange Commission has not necessarily reviewed the information in this filing and has not determined if it is accurate and complete.
The reader should not assume that the information is accurate and complete.

UNITED STATES SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549
FORM 13F

FORM 13F INFORMATION TABLE
OMB APPROVAL
OMB Number: 3235-0006
Estimated average burden
hours per response: 23.8
COLUMN 1 COLUMN 2 COLUMN 3 COLUMN 4 COLUMN 5 COLUMN 6 COLUMN 7 COLUMN 8
VALUE SHRS OR SH/ PUT/ INVESTMENT OTHER VOTING AUTHORITY
NAME OF ISSUER TITLE OF CLASS CUSIP (x$1000) PRN AMT PRN CALL DISCRETION MANAGER SOLE SHARED NONE
10X GENOMICS INC COMMON 88025U109 2 21 SH   DFND   21 0 0
21VIANET GROUP INC-ADR ADR 90138A103 1,730 296,796 SH   DFND   296,796 0 0
21VIANET GROUP INC-ADR ADR 90138A103 188 32,253 SH   DFND 2 32,253 0 0
3M CO COMMON 88579Y101 19 126 SH   DFND   126 0 0
AARONS CO INC/THE COMMON 00258W108 8,829 439,697 SH   DFND   411,710 0 27,987
ABBOTT LABS COMMON 002824100 23,258 196,505 SH   DFND   194,163 0 2,342
ABBOTT LABS COMMON 002824100 2,095 17,698 SH   DFND 2 17,698 0 0
ABBVIE INC COMMON 00287Y109 45,055 277,926 SH   DFND   272,536 0 5,390
ABBVIE INC COMMON 00287Y109 3,920 24,180 SH   DFND 2 24,180 0 0
ACADIA HEALTHCARE CO INC COMMON 00404A109 43,964 670,902 SH   DFND   595,711 0 75,191
ACADIA HEALTHCARE CO INC COMMON 00404A109 19,284 294,273 SH   DFND 2 294,273 0 0
ACCENTURE LTD CL A COMMON G1151C101 361,344 1,071,507 SH   DFND   742,978 0 328,529
ACCENTURE LTD CL A COMMON G1151C101 2,727 8,087 SH   DFND 2 8,087 0 0
ACTIVISION BLIZZARD INC COMMON 00507V109 12 147 SH   DFND   147 0 0
ACUITY BRANDS INC COMMON 00508Y102 5 28 SH   DFND   28 0 0
ADOBE SYS COMMON 00724F101 167,731 368,138 SH   DFND   245,728 0 122,410
ADVANCE AUTO PARTS INC COMMON 00751Y106 12 58 SH   DFND   58 0 0
ADVANCED DRAINAGE SYSTEMS IN COMMON 00790R104 87,501 736,482 SH   DFND   690,393 0 46,089
ADVANCED DRAINAGE SYSTEMS IN COMMON 00790R104 26,515 223,174 SH   DFND 2 223,174 0 0
ADVANCED ENERGY INDS COMMON 007973100 54,283 630,616 SH   DFND   586,277 0 44,339
ADVANCED ENERGY INDS COMMON 007973100 15,054 174,883 SH   DFND 2 174,883 0 0
ADVANCED MICRO COMMON 007903107 1,106 10,112 SH   DFND   418 0 9,694
AECOM TECHNOLOGY CORP COMMON 00766T100 50,290 654,730 SH   DFND   347,453 0 307,277
AECOM TECHNOLOGY CORP COMMON 00766T100 2,570 33,460 SH   DFND 2 33,460 0 0
AERIE PHARMACEUTICALS CV BND 00771VAB4 1,301 142,943 SH   DFND   135,535 0 7,407
AERIE PHARMACEUTICALS CV BND 00771VAB4 2,252 247,447 SH   DFND 2 247,447 0 0
AES CORPORATION COMMON 00130H105 263 10,218 SH   DFND   10,218 0 0
AES CORPORATION COMMON 00130H105 107 4,146 SH   DFND 2 4,146 0 0
AFFIRM HOLDINGS INC COMMON 00827B106 178 3,849 SH   DFND   3,849 0 0
AFLAC INC COMMON 001055102 10 160 SH   DFND   160 0 0
AGCO CORP COMMON 001084102 7 51 SH   DFND   51 0 0
AGILENT TECHNOLOGIES INC COMMON 00846U101 2 18 SH   DFND   18 0 0
AGREE REALTY CORP COMMON 008492100 25,354 382,067 SH   DFND   224,020 0 158,047
AGREE REALTY CORP COMMON 008492100 991 14,939 SH   DFND 2 14,939 0 0
AIR LEASE CORP COMMON 00912X302 3 63 SH   DFND   63 0 0
AIR PRODS & CHEM COMMON 009158106 11 44 SH   DFND   44 0 0
AIRBNB INC COMMON 009066101 454,874 2,648,313 SH   DFND   1,768,392 0 879,921
AKAMAI TECHNOLOGIES COMMON 00971T101 3 24 SH   DFND   24 0 0
ALBANY INTL CORP-CL A COMMON 012348108 53,081 629,520 SH   DFND   611,899 0 17,621
ALBANY INTL CORP-CL A COMMON 012348108 7,155 84,860 SH   DFND 2 84,860 0 0
ALBERTSONS COS INC - CLASS A COMMON 013091103 3 101 SH   DFND   101 0 0
ALCOA CORP COMMON 013872106 8 93 SH   DFND   93 0 0
ALEXANDRIA REAL ESTATE EQUITIES INC. COMMON 015271109 2 9 SH   DFND   9 0 0
ALIBABA GROUP HOLDING-SP ADR ADR 01609W102 683,816 6,285,078 SH   DFND   4,859,295 0 1,425,783
ALIBABA GROUP HOLDING-SP ADR ADR 01609W102 74,624 685,878 SH   DFND 2 685,878 0 0
ALIGHT INC - CLASS A COMMON 01626W101 20,354 2,045,630 SH   DFND   590,065 0 1,455,565
ALIGHT INC - CLASS A COMMON 01626W101 1,633 164,105 SH   DFND 2 164,105 0 0
ALIGN TECHNOLOGY INC COMMON 016255101 2 5 SH   DFND   5 0 0
ALLEGION PLC COMMON G0176J109 76 695 SH   DFND   47 0 648
ALLEGRO MICROSYSTEMS INC COMMON 01749D105 2 87 SH   DFND   87 0 0
ALLETE INC COMMON 018522300 12,052 179,930 SH   DFND   168,018 0 11,912
ALLIANCE DATA SYSTEMS CORP COMMON 018581108 5 82 SH   DFND   82 0 0
ALLIANT ENERGY CORP COMMON 018802108 5 83 SH   DFND   83 0 0
ALLISON TRANSMISSION HOLDING COMMON 01973R101 6 164 SH   DFND   164 0 0
ALLSCRIPTS INC COMMON 01988P108 34,247 1,520,724 SH   DFND   1,019,597 0 501,127
ALLSCRIPTS INC COMMON 01988P108 1,252 55,590 SH   DFND 2 55,590 0 0
ALLSTATE CORP COMMON 020002101 15 110 SH   DFND   110 0 0
ALLY FINANCIAL INC COMMON 02005N100 5 121 SH   DFND   121 0 0
ALNYLAM PHARMACEUTICALS INC COMMON 02043Q107 136,425 835,477 SH   DFND   738,918 0 96,559
ALNYLAM PHARMACEUTICALS INC COMMON 02043Q107 5,433 33,271 SH   DFND 2 33,271 0 0
ALPHABET INC-CL A COMMON 02079K305 2,530,022 909,638 SH   DFND   692,400 0 217,238
ALPHABET INC-CL A COMMON 02079K305 223,559 80,378 SH   DFND 2 80,378 0 0
ALPHABET INC-CL C COMMON 02079K107 1,721,214 616,262 SH   DFND   478,873 0 137,389
ALPHABET INC-CL C COMMON 02079K107 177,983 63,725 SH   DFND 2 63,725 0 0
ALTA EQUIPMENT GROUP INC COMMON 02128L106 6,734 544,843 SH   DFND   508,243 0 36,600
ALTICE USA INC- A COMMON 02156K103 63,604 5,096,449 SH   DFND   4,935,997 0 160,452
ALTICE USA INC- A COMMON 02156K103 19,726 1,580,623 SH   DFND 2 1,580,623 0 0
ALTRA INDUSTRIAL MOTION CORP COMMON 02208R106 11,320 290,790 SH   DFND   270,169 0 20,621
ALTRIA GROUP INC COMMON 02209S103 25 486 SH   DFND   486 0 0
AMAZON.COM INC COMMON 023135106 3,894,480 1,194,644 SH   DFND   920,355 0 274,289
AMAZON.COM INC COMMON 023135106 365,052 111,981 SH   DFND 2 111,981 0 0
AMBEV SA-SPN ADR ADR 02319V103 61,065 18,905,589 SH   DFND   18,515,657 0 389,932
AMBEV SA-SPN ADR ADR 02319V103 3,453 1,069,030 SH   DFND 2 1,069,030 0 0
AMCOR PLC COMMON G0250X107 8 695 SH   DFND   695 0 0
AMDOCS LTD COMMON G02602103 3 38 SH   DFND   38 0 0
AMEDISYS INC COMMON 023436108 3 19 SH   DFND   19 0 0
AMERCO COMMON 023586100 5 9 SH   DFND   9 0 0
AMEREN CORPORATION COMMON 023608102 9 94 SH   DFND   94 0 0
AMERICAN AIRLINES GROUP CVT CV BND 02376RAF9 2,332 127,778 SH   DFND   90,123 0 37,654
AMERICAN AIRLINES GROUP CVT CV BND 02376RAF9 3,864 211,728 SH   DFND 2 211,728 0 0
AMERICAN ELEC PWR COMMON 025537101 22 220 SH   DFND   220 0 0
AMERICAN ELECTRIC POWER CVTPFD 6.125 CV PFD 02557T307 505 5,062 SH   DFND   3,946 0 1,115
AMERICAN ELECTRIC POWER CVTPFD 6.125 CV PFD 02557T307 613 6,140 SH   DFND 2 6,140 0 0
AMERICAN EXPRESS CO COMMON 025816109 5 28 SH   DFND   28 0 0
AMERICAN FINANCIAL GROUP INC COMMON 025932104 24 166 SH   DFND   166 0 0
AMERICAN HOMES 4 RENT- A COMMON 02665T306 2 48 SH   DFND   48 0 0
AMERICAN INTL GRP INC COMMON 026874784 13 201 SH   DFND   201 0 0
AMERICAN TOWER CORPORATION COMMON 03027X100 35,359 140,748 SH   DFND   139,061 0 1,687
AMERICAN TOWER CORPORATION COMMON 03027X100 3,008 11,975 SH   DFND 2 11,975 0 0
AMERICAN WATER WORKS CO INC COMMON 030420103 10,042 60,664 SH   DFND   17,934 0 42,730
AMERICAN WATER WORKS CO INC COMMON 030420103 711 4,295 SH   DFND 2 4,295 0 0
AMERICOLD REALTY TRUST COMMON 03064D108 20 710 SH   DFND   0 0 710
AMERIPRISE FINANCIAL INC COMMON 03076C106 13 44 SH   DFND   44 0 0
AMERIS BANCORP COMMON 03076K108 44,305 1,009,689 SH   DFND   975,373 0 34,316
AMERIS BANCORP COMMON 03076K108 5,063 115,383 SH   DFND 2 115,383 0 0
AMGEN INC COMMON 031162100 21 88 SH   DFND   88 0 0
AMN HEALTHCARE SERVICES INC COMMON 001744101 15,767 151,129 SH   DFND   89,433 0 61,696
AMN HEALTHCARE SERVICES INC COMMON 001744101 697 6,680 SH   DFND 2 6,680 0 0
AMPHENOL CORP CL A COMMON 032095101 18 237 SH   DFND   237 0 0
ANALOG DEVICES INC COMMON 032654105 24 148 SH   DFND   148 0 0
ANAPLAN INC COMMON 03272L108 326 5,008 SH   DFND   0 0 5,008
ANDERSONS INC COMMON 034164103 7,076 140,795 SH   DFND   129,037 0 11,758
ANGIODYNAMICS INC COMMON 03475V101 16,942 786,515 SH   DFND   648,860 0 137,655
ANGIODYNAMICS INC COMMON 03475V101 10,348 480,402 SH   DFND 2 480,402 0 0
ANSYS INC COMMON 03662Q105 2 7 SH   DFND   7 0 0
ANTERO MIDSTREAM CORP COMMON 03676B102 13 1,152 SH   DFND   1,152 0 0
ANTERO RESOURCES CORP COMMON 03674X106 17,091 559,811 SH   DFND   521,002 0 38,809
ANTHEM INC COMMON 036752103 21,892 44,567 SH   DFND   44,027 0 540
ANTHEM INC COMMON 036752103 1,711 3,483 SH   DFND 2 3,483 0 0
AON PLC COMMON G0403H108 12 36 SH   DFND   36 0 0
APACHE CORP COMMON 03743Q108 8 182 SH   DFND   182 0 0
API GROUP CORP COMMON 00187Y100 13,861 659,091 SH   DFND   195,353 0 463,738
API GROUP CORP COMMON 00187Y100 1,187 56,420 SH   DFND 2 56,420 0 0
APPLE HOSPITALITY REIT INC COMMON 03784Y200 1 67 SH   DFND   67 0 0
APPLE INC COMMON 037833100 44,627 255,583 SH   DFND   218,809 0 36,774
APPLE INC COMMON 037833100 4,535 25,973 SH   DFND 2 25,973 0 0
APPLIED INDUSTRIAL TECH INC COMMON 03820C105 7,253 70,648 SH   DFND   69,465 0 1,183
APPLIED INDUSTRIAL TECH INC COMMON 03820C105 1,284 12,511 SH   DFND 2 12,511 0 0
APPLIED MATERIALS COMMON 038222105 1,752 13,294 SH   DFND   8,850 0 4,444
APPLIED MATERIALS COMMON 038222105 260 1,971 SH   DFND 2 1,971 0 0
APTARGROUP INC COMMON 038336103 3 24 SH   DFND   24 0 0
APTIV PLC COMMON G6095L109 2 18 SH   DFND   18 0 0
ARCH CAPITAL GROUP LTD COMMON G0450A105 3 69 SH   DFND   69 0 0
ARCHER-DANIELS-MIDLAND CO COMMON 039483102 597 6,614 SH   DFND   3,209 0 3,405
ARCHER-DANIELS-MIDLAND CO COMMON 039483102 117 1,293 SH   DFND 2 1,293 0 0
ARCONIC ROLLED PRODUCTS CORP COMMON 03966V107 13,034 508,739 SH   DFND   473,082 0 35,657
ARCOSA INC COMMON 039653100 33,713 588,880 SH   DFND   360,717 0 228,163
ARCOSA INC COMMON 039653100 1,338 23,368 SH   DFND 2 23,368 0 0
ARES CAPITAL CORP COMMON 04010L103 621 29,632 SH   DFND   29,632 0 0
ARES CAPITAL CORP COMMON 04010L103 276 13,190 SH   DFND 2 13,190 0 0
ARES MANAGEMENT CORP - A COMMON 03990B101 27,217 335,057 SH   DFND   276,462 0 58,595
ARES MANAGEMENT CORP - A COMMON 03990B101 16,761 206,334 SH   DFND 2 206,334 0 0
ARGENX SE - ADR ADR 04016X101 17,399 55,180 SH   DFND   45,528 0 9,652
ARGENX SE - ADR ADR 04016X101 10,623 33,690 SH   DFND 2 33,690 0 0
ARISTA NETWORKS INC COMMON 040413106 444 3,192 SH   DFND   24 0 3,168
ARISTA NETWORKS INC COMMON 040413106 46 328 SH   DFND 2 328 0 0
ARROW ELECTRS COMMON 042735100 3 22 SH   DFND   22 0 0
ASHLAND GLOBAL HOLDINGS INC COMMON 044186104 15,650 159,025 SH   DFND   115,128 0 43,897
ASHLAND GLOBAL HOLDINGS INC COMMON 044186104 917 9,314 SH   DFND 2 9,314 0 0
ASPEN TECHNOLOGY INC COMMON 045327103 3 19 SH   DFND   19 0 0
ASSURANT INC COMMON 04621X108 12 66 SH   DFND   66 0 0
AT&T INC COMMON 00206R102 300 12,706 SH   DFND   12,706 0 0
ATKORE INTERNATIONAL GROUP I COMMON 047649108 11,167 113,439 SH   DFND   106,005 0 7,434
ATLANTIC UNION BANKSHARES CORP COMMON 04911A107 14,259 388,624 SH   DFND   363,702 0 24,922
ATLAS AIR WORLDWIDE HLDG CVT CV BND 049164BJ4 3,370 39,013 SH   DFND   30,500 0 8,513
ATLAS AIR WORLDWIDE HLDG CVT CV BND 049164BJ4 3,987 46,167 SH   DFND 2 46,167 0 0
ATMOS ENERGY CORP COMMON 049560105 3 27 SH   DFND   27 0 0
ATRICURE INC COMMON 04963C209 51,600 785,744 SH   DFND   772,621 0 13,123
ATRICURE INC COMMON 04963C209 9,148 139,295 SH   DFND 2 139,295 0 0
AUTODESK INC COMMON 052769106 1,607,082 7,497,468 SH   DFND   5,796,330 0 1,701,138
AUTODESK INC COMMON 052769106 175,978 820,983 SH   DFND 2 820,983 0 0
AUTOMATIC DATA PROC COMMON 053015103 17,070 75,019 SH   DFND   69,583 0 5,436
AUTOMATIC DATA PROC COMMON 053015103 1,393 6,120 SH   DFND 2 6,120 0 0
AUTONATION INC COMMON 05329W102 6 56 SH   DFND   56 0 0
AUTOZONE INC COMMON 053332102 14 7 SH   DFND   7 0 0
AVANGRID INC COMMON 05351W103 8 181 SH   DFND   181 0 0
AVANTOR INC COMMON 05352A100 21,327 630,594 SH   DFND   186,383 0 444,211
AVANTOR INC COMMON 05352A100 1,706 50,437 SH   DFND 2 50,437 0 0
AVAYA HOLDINGS CORP COMMON 05351X101 0 1 SH   DFND   1 0 0
AVID TECHNOLOGY INC COMMON 05367P100 12,958 371,602 SH   DFND   306,715 0 64,887
AVID TECHNOLOGY INC COMMON 05367P100 7,950 228,002 SH   DFND 2 228,002 0 0
AVNET INC COMMON 053807103 3 70 SH   DFND   70 0 0
AXALTA COATING SYSTEMS LTD COMMON G0750C108 2 94 SH   DFND   94 0 0
AXON ENTERPRISE INC COMMON 05464C101 22,592 164,033 SH   DFND   135,349 0 28,684
AXON ENTERPRISE INC COMMON 05464C101 13,798 100,182 SH   DFND 2 100,182 0 0
AXONICS MODULATION TECHNOLOG COMMON 05465P101 74,468 1,189,586 SH   DFND   1,119,357 0 70,229
AXONICS MODULATION TECHNOLOG COMMON 05465P101 21,835 348,801 SH   DFND 2 348,801 0 0
AXOS FINANCIAL INC COMMON 05465C100 19,947 429,978 SH   DFND   354,745 0 75,233
AXOS FINANCIAL INC COMMON 05465C100 12,186 262,677 SH   DFND 2 262,677 0 0
AZENTA INC COMMON 114340102 22,956 276,982 SH   DFND   184,780 0 92,202
AZZ INC COMMON 002474104 3,682 76,324 SH   DFND   71,197 0 5,127
BAIDU.COM ADR 056752108 35,891 271,286 SH   DFND   264,916 0 6,370
BAIDU.COM ADR 056752108 2,164 16,355 SH   DFND 2 16,355 0 0
BAKER HUGHS CO COMMON 05722G100 5 124 SH   DFND   124 0 0
BAKER HUGHS CO COMMON 05722G100 159 4,356 SH   DFND 2 4,356 0 0
BALL CORPORATION COMMON 058498106 5 52 SH   DFND   52 0 0
BANCO BILBAO VIZCAYA -SP ADR ADR 05946K101 77 13,565 SH   DFND   13,565 0 0
BANCORP INC COMMON 05969A105 37,970 1,340,292 SH   DFND   1,317,907 0 22,385
BANCORP INC COMMON 05969A105 6,731 237,587 SH   DFND 2 237,587 0 0
BANK OF AMERICA CORP COMMON 060505104 82 1,985 SH   DFND   1,985 0 0
BANK OF NEW YORK MELLON CORP COMMON 064058100 13 256 SH   DFND   256 0 0
Bank OZK COMMON 06417N103 179 4,199 SH   DFND   0 0 4,199
BATH & BODY WORKS INC COMMON 070830104 12,032 251,721 SH   DFND   119,436 0 132,285
BATH & BODY WORKS INC COMMON 070830104 1,524 31,877 SH   DFND 2 31,877 0 0
BATTALION OIL CORP COMMON 07134L107 5,223 281,110 SH   DFND   254,011 4,815 22,284
BATTALION OIL CORP COMMON 07134L107 768 41,352 SH   DFND 2 41,352 0 0
BAUSCH HEALTH COS INC COMMON 071734107 11 494 SH   DFND   0 0 494
BAXTER INTL COMMON 071813109 12 158 SH   DFND   158 0 0
BECTON DICKINSON & CO COMMON 075887109 15 55 SH   DFND   55 0 0
BERKSHIRE HATHAWAY INC CL B COMMON 084670702 270 764 SH   DFND   207 0 557
BEST BUY COMPANY COMMON 086516101 12 132 SH   DFND   132 0 0
BICYCLE THERAPEUTICS LTD-ADR ADR 088786108 23,995 546,840 SH   DFND   537,716 0 9,124
BICYCLE THERAPEUTICS LTD-ADR ADR 088786108 4,254 96,935 SH   DFND 2 96,935 0 0
BIO-RAD LABORATORIES-CL A COMMON 090572207 446 791 SH   DFND   34 0 757
BIO-TECHNE CORPORAT COMMON 09073M104 19,840 45,815 SH   DFND   37,803 0 8,012
BIO-TECHNE CORPORAT COMMON 09073M104 12,103 27,948 SH   DFND 2 27,948 0 0
BIOCRYST PHARMACEUTICALS INC COMMON 09058V103 32,550 2,001,857 SH   DFND   1,968,491 0 33,366
BIOCRYST PHARMACEUTICALS INC COMMON 09058V103 5,762 354,359 SH   DFND 2 354,359 0 0
BIOGEN INC COMMON 09062X103 9 44 SH   DFND   44 0 0
BIOMARIN PHARMACEUTICAL CVT CV BND 09061GAH4 60,654 786,695 SH   DFND   738,849 1,524 46,322
BIOMARIN PHARMACEUTICAL CVT CV BND 09061GAH4 8,858 114,896 SH   DFND 2 114,896 0 0
BIOMARIN PHARMACEUTICAL CVT CV BND 09061GAK7 147,225 1,909,533 SH   DFND   1,751,433 5,347 152,753
BIOMARIN PHARMACEUTICAL CVT CV BND 09061GAK7 28,393 368,261 SH   DFND 2 368,261 0 0
BIOMARIN PHARMACEUTICAL INC COMMON 09061G101 29,547 383,226 SH   DFND   312,135 0 71,091
BIOMARIN PHARMACEUTICAL INC COMMON 09061G101 921 11,945 SH   DFND 2 11,945 0 0
BJS WHOLESALE CLUB HOLDINGS COMMON 05550J101 28,460 420,940 SH   DFND   347,266 0 73,674
BJS WHOLESALE CLUB HOLDINGS COMMON 05550J101 17,383 257,109 SH   DFND 2 257,109 0 0
BLACKLINE INC COMMON 09239B109 36,285 495,557 SH   DFND   461,527 0 34,030
BLACKLINE INC COMMON 09239B109 11,602 158,455 SH   DFND 2 158,455 0 0
BLACKROCK INC COMMON 09247X101 40,050 52,410 SH   DFND   51,770 0 640
BLACKROCK INC COMMON 09247X101 3,265 4,273 SH   DFND 2 4,273 0 0
BLACKSTONE GROUP LP COMMON 09260D107 650 5,120 SH   DFND   5,120 0 0
BLACKSTONE GROUP LP COMMON 09260D107 270 2,129 SH   DFND 2 2,129 0 0
BLOCK INC COMMON 852234103 787,072 5,804,366 SH   DFND   4,546,208 0 1,258,158
BLOCK INC COMMON 852234103 84,117 620,330 SH   DFND 2 620,330 0 0
BLUEPRINT MEDICINES CORP COMMON 09627Y109 23,767 372,064 SH   DFND   365,850 0 6,214
BLUEPRINT MEDICINES CORP COMMON 09627Y109 4,213 65,958 SH   DFND 2 65,958 0 0
BOEING CO COMMON 097023105 2,202,773 11,502,729 SH   DFND   9,165,416 0 2,337,313
BOEING CO COMMON 097023105 237,265 1,238,984 SH   DFND 2 1,238,984 0 0
BOOKING HOLDINGS INC COMMON 09857L108 1,543 657 SH   DFND   657 0 0
BOOKING HOLDINGS INC COMMON 09857L108 592 252 SH   DFND 2 252 0 0
BOOT BARN HOLDINGS INC COMMON 099406100 35,655 376,149 SH   DFND   369,868 0 6,281
BOOT BARN HOLDINGS INC COMMON 099406100 6,320 66,677 SH   DFND 2 66,677 0 0
BORG WARNER INC COMMON 099724106 0 5 SH   DFND   0 0 5
BOSTON BEER COMPANY CL A COMMON 100557107 37,693 97,030 SH   DFND   79,759 0 17,271
BOSTON BEER COMPANY CL A COMMON 100557107 1,166 3,002 SH   DFND 2 3,002 0 0
BOSTON PROPERTIES INC COMMON 101121101 2 16 SH   DFND   16 0 0
BOSTON SCIENTIFIC CORP COMMON 101137107 14 316 SH   DFND   316 0 0
BOYD GAMING CORP COMMON 103304101 6 90 SH   DFND   90 0 0
BRANDYWINE RLTY TRUST COMMON 105368203 0 21 SH   DFND   21 0 0
BRISTOL MYERS SQUIBB COMMON 110122108 27,393 375,098 SH   DFND   368,333 0 6,765
BRISTOL MYERS SQUIBB COMMON 110122108 2,478 33,933 SH   DFND 2 33,933 0 0
BROADCOM INC COMMON 11135F101 23,438 37,222 SH   DFND   34,753 0 2,469
BROADCOM INC COMMON 11135F101 1,974 3,135 SH   DFND 2 3,135 0 0
BROADRIDGE FINANCIAL SOLUTIONS INC COMMON 11133T103 20,153 129,426 SH   DFND   106,789 0 22,637
BROADRIDGE FINANCIAL SOLUTIONS INC COMMON 11133T103 12,309 79,054 SH   DFND 2 79,054 0 0
BROWN & BROWN INC COMMON 115236101 3 45 SH   DFND   45 0 0
BROWN FORMAN CORP CL A COMMON 115637100 3 41 SH   DFND   41 0 0
BROWN FORMAN CORP CL B COMMON 115637209 3 39 SH   DFND   39 0 0
BRP GROUP INC-A COMMON 05589G102 25,008 932,088 SH   DFND   916,534 0 15,554
BRP GROUP INC-A COMMON 05589G102 4,433 165,225 SH   DFND 2 165,225 0 0
BRUNSWICK CORP COMMON 117043109 31,411 388,321 SH   DFND   337,903 0 50,418
BRUNSWICK CORP COMMON 117043109 11,458 141,651 SH   DFND 2 141,651 0 0
BUILDERS FIRSTSOURCE INC COMMON 12008R107 192 2,974 SH   DFND   264 0 2,710
BUNGE LIMITED COMMON G16962105 12 106 SH   DFND   106 0 0
BWX TECHNOLOGIES INC COMMON 05605H100 3 61 SH   DFND   61 0 0
C.H. ROBINSON WORLDWIDE COMMON 12541W209 6 55 SH   DFND   55 0 0
CABLE ONE INC COMMON 12685J105 3 2 SH   DFND   2 0 0
CABOT CORP COMMON 127055101 12,497 182,676 SH   DFND   171,511 0 11,165
CACTUS INC-CLASS A COMMON 127203107 57,061 1,005,658 SH   DFND   988,859 0 16,799
CACTUS INC-CLASS A COMMON 127203107 10,114 178,249 SH   DFND 2 178,249 0 0
CADENCE DESIGN SYS INC COMMON 127387108 457 2,780 SH   DFND   102 0 2,678
CALIFORNIA RESOURCES CORP COMMON 13057Q305 10,700 239,207 SH   DFND   226,296 0 12,911
CALIFORNIA RESOURCES CORP COMMON 13057Q305 994 22,215 SH   DFND 2 22,215 0 0
CALIX INC COMMON 13100M509 30,956 721,408 SH   DFND   709,371 0 12,037
CALIX INC COMMON 13100M509 5,488 127,887 SH   DFND 2 127,887 0 0
CAMPBELL SOUP COMMON 134429109 3 66 SH   DFND   66 0 0
CANNAE HOLDINGS INC COMMON 13765N107 9,490 396,719 SH   DFND   370,186 0 26,533
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HP INC COMMON 40434L105 13 353 SH   DFND   353 0 0
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IBM COMMON 459200101 7 50 SH   DFND   50 0 0
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INSTALLED BUILDING PRODUCTS COMMON 45780R101 4,986 59,013 SH   DFND 2 59,013 0 0
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VERIZON COMMUNICATIONS COMMON 92343V104 289 5,674 SH   DFND 2 5,674 0 0
VERTEX PHARMACEUTICALS INC COMMON 92532F100 1,500,718 5,750,540 SH   DFND   4,441,732 0 1,308,808
VERTEX PHARMACEUTICALS INC COMMON 92532F100 166,625 638,483 SH   DFND 2 638,483 0 0
VERTIV HOLDINGS CO COMMON 92537N108 87 6,217 SH   DFND   122 0 6,095
VIACOMCBS INC COMMON 92556H206 3 90 SH   DFND   90 0 0
VIACOMCBS INC CL A COMMON 92556H107 3 81 SH   DFND   81 0 0
VIAVI SOLUTION INC COMMON 925550105 15,696 976,110 SH   DFND   913,465 0 62,645
VICTORIAS SECRET & CO COMMON 926400102 10 187 SH   DFND   136 0 51
VIPSHOP HOLDINGS LTD - ADS ADR 92763W103 414 45,970 SH   DFND   45,970 0 0
VIPSHOP HOLDINGS LTD - ADS ADR 92763W103 113 12,549 SH   DFND 2 12,549 0 0
VIRTU FINANCIAL INC-CLASS A COMMON 928254101 4 98 SH   DFND   98 0 0
VISA INC-CLASS A SHRS COMMON 92826C839 2,859,057 12,891,989 SH   DFND   10,063,824 0 2,828,165
VISA INC-CLASS A SHRS COMMON 92826C839 312,406 1,408,693 SH   DFND 2 1,408,693 0 0
VISHAY INTERTECHNOLOGY CVT CV BND 928298AP3 307 15,655 SH   DFND   11,981 0 3,674
VISHAY INTERTECHNOLOGY CVT CV BND 928298AP3 391 19,968 SH   DFND 2 19,968 0 0
VISTRA ENERGY CORP COMMON 92840M102 13,506 580,900 SH   DFND   173,403 0 407,497
VISTRA ENERGY CORP COMMON 92840M102 1,112 47,846 SH   DFND 2 47,846 0 0
VONTIER CORP-W/I COMMON 928881101 38,253 1,506,636 SH   DFND   845,366 0 661,270
VONTIER CORP-W/I COMMON 928881101 1,626 64,058 SH   DFND 2 64,058 0 0
VSE CORP COMMON 918284100 5,510 119,548 SH   DFND   111,220 0 8,328
VTEX -CLASS A COMMON G9470A102 843 137,120 SH   DFND   137,120 0 0
VTEX -CLASS A COMMON G9470A102 257 41,853 SH   DFND 2 41,853 0 0
WABASH NATIONAL CORP COMMON 929566107 6,132 413,236 SH   DFND   383,934 0 29,302
WAL-MART STORES INC COMMON 931142103 41,703 280,033 SH   DFND   275,720 0 4,313
WAL-MART STORES INC COMMON 931142103 3,572 23,985 SH   DFND 2 23,985 0 0
WALGREEN CO COMMON 931427108 4 83 SH   DFND   83 0 0
WASTE CONNECTIONS INC COMMON 94106B101 161 1,152 SH   DFND 2 1,152 0 0
WASTE MANAGEMENT INC COMMON 94106L109 27 168 SH   DFND   168 0 0
WATERS CORP COMMON 941848103 5 16 SH   DFND   16 0 0
WATSCO INC COMMON 942622200 3 9 SH   DFND   9 0 0
WEC ENERGY GROUP COMMON 92939U106 3 30 SH   DFND   30 0 0
WELLS FARGO & CO COMMON 949746101 427 8,821 SH   DFND   8,821 0 0
WELLS FARGO & CO COMMON 949746101 162 3,335 SH   DFND 2 3,335 0 0
WEST PHARMACEUTICALS SVCS COMMON 955306105 6 14 SH   DFND   14 0 0
WESTERN ALLIANCE BANCORP COMMON 957638109 3 32 SH   DFND   32 0 0
WESTERN ALLIANCE BANCORP COMMON 957638109 61 735 SH   DFND 2 735 0 0
WESTERN DIGITAL CORP COMMON 958102105 2 46 SH   DFND   46 0 0
WESTERN UNION CO/THE COMMON 959802109 8 448 SH   DFND   448 0 0
WESTLAKE CHEMICAL CORP COMMON 960413102 6 46 SH   DFND   46 0 0
WEX INC COMMON 96208T104 27,868 156,166 SH   DFND   58,086 0 98,080
WEX INC COMMON 96208T104 1,667 9,339 SH   DFND 2 9,339 0 0
WEYERHAEUSER CO COMMON 962166104 242 6,381 SH   DFND   0 0 6,381
WHIRLPOOL CORP COMMON 963320106 11 61 SH   DFND   61 0 0
WHITING PETROLEUM CORP COMMON 966387508 3 38 SH   DFND   38 0 0
WHOLE EARTH BRANDS INC COMMON 96684W100 7,950 1,110,344 SH   DFND   1,034,320 0 76,024
WILEY JOHN & SONS CL A COMMON 968223206 8,054 151,877 SH   DFND   142,331 0 9,546
WILLIAMS COS INC COMMON 969457100 23,583 705,853 SH   DFND   697,287 0 8,566
WILLIAMS COS INC COMMON 969457100 1,912 57,220 SH   DFND 2 57,220 0 0
WILLIAMS SONOMA INC COMMON 969904101 258 1,778 SH   DFND   18 0 1,760
WILLSCOT MOBILE MINI HOLDINGS COMMON 971378104 68,944 1,761,914 SH   DFND   1,683,333 0 78,581
WILLSCOT MOBILE MINI HOLDINGS COMMON 971378104 17,535 448,119 SH   DFND 2 448,119 0 0
WINGSTOP INC COMMON 974155103 36,796 313,555 SH   DFND   308,319 0 5,236
WINGSTOP INC COMMON 974155103 6,523 55,584 SH   DFND 2 55,584 0 0
WINTRUST FINANCIAL CORP COMMON 97650W108 22,209 238,983 SH   DFND   223,312 0 15,671
WNS HOLDINGS LTD-ADR ADR 92932M101 59,965 701,424 SH   DFND   689,710 0 11,714
WNS HOLDINGS LTD-ADR ADR 92932M101 10,630 124,337 SH   DFND 2 124,337 0 0
WOODWARD INC COMMON 980745103 12,377 99,086 SH   DFND   81,749 0 17,337
WOODWARD INC COMMON 980745103 7,609 60,914 SH   DFND 2 60,914 0 0
WORKDAY INC COMMON 98138H101 671,662 2,804,904 SH   DFND   2,169,643 0 635,261
WORKDAY INC COMMON 98138H101 69,137 288,719 SH   DFND 2 288,719 0 0
WR BERKLEY CORP COMMON 084423102 238 3,570 SH   DFND   3,570 0 0
WSFS FINANCIAL CORP COMMON 929328102 12,989 278,608 SH   DFND   260,770 0 17,838
WYNN RESORTS LTD COMMON 983134107 272 3,417 SH   DFND   3,417 0 0
XCEL ENERGY INC COMMON 98389B100 6 81 SH   DFND   81 0 0
XENCOR INC COMMON 98401F105 36,797 1,379,182 SH   DFND   1,285,236 0 93,946
XENCOR INC COMMON 98401F105 11,709 438,875 SH   DFND 2 438,875 0 0
XEROX HOLDINGS CORP COMMON 98421M106 13 658 SH   DFND   658 0 0
XYLEM INC COMMON 98419M100 2 25 SH   DFND   25 0 0
YANDEX NV-A COMMON N97284108 352 70,673 SH   DFND   70,673 0 0
YANDEX NV-A COMMON N97284108 67 13,410 SH   DFND 2 13,410 0 0
YUM CHINA HOLDINGS INC COMMON 98850P109 320,162 7,707,310 SH   DFND   6,067,572 0 1,639,738
YUM CHINA HOLDINGS INC COMMON 98850P109 33,756 812,622 SH   DFND 2 812,622 0 0
YUM! BRANDS INC COMMON 988498101 591,374 4,989,233 SH   DFND   3,822,036 0 1,167,197
YUM! BRANDS INC COMMON 988498101 66,901 564,420 SH   DFND 2 564,420 0 0
ZETA GLOBAL HOLDINGS CORP-A COMMON 98956A105 4,843 379,853 SH   DFND   313,570 0 66,283
ZETA GLOBAL HOLDINGS CORP-A COMMON 98956A105 2,969 232,898 SH   DFND 2 232,898 0 0
ZILLOW GROUP INC CVT CV BND 98954MAG6 5,109 103,653 SH   DFND   87,680 575 15,399
ZILLOW GROUP INC CVT CV BND 98954MAG6 963 19,536 SH   DFND 2 19,536 0 0
ZIMMER BIOMET HOLDINGS INC COMMON 98956P102 8 64 SH   DFND   64 0 0
ZIONS BANCORP COMMON 989701107 10 148 SH   DFND   148 0 0
ZOETIS INC COMMON 98978V103 15 82 SH   DFND   82 0 0
ZOOM VIDEO COMMUNICATIONS-A COMMON 98980L101 4 34 SH   DFND   34 0 0
ZSCALER INC. CVT CV BND 98980GAB8 6,482 26,864 SH   DFND   20,796 0 6,068
ZSCALER INC. CVT CV BND 98980GAB8 8,368 34,683 SH   DFND 2 34,683 0 0