The Securities and Exchange Commission has not necessarily reviewed the information in this filing and has not determined if it is accurate and complete.
The reader should not assume that the information is accurate and complete.

UNITED STATES SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549
FORM 13F

FORM 13F INFORMATION TABLE
OMB APPROVAL
OMB Number: 3235-0006
Estimated average burden
hours per response: 23.8
COLUMN 1 COLUMN 2 COLUMN 3 COLUMN 4 COLUMN 5 COLUMN 6 COLUMN 7 COLUMN 8
VALUE SHRS OR SH/ PUT/ INVESTMENT OTHER VOTING AUTHORITY
NAME OF ISSUER TITLE OF CLASS CUSIP FIGI (to the nearest dollar) PRN AMT PRN CALL DISCRETION MANAGER SOLE SHARED NONE
2SEVENTY BIO INC COMMON STOCK 901384107   5,350 1,000 SH   SOLE   5,350 0 0
4D MOLECULAR THERAPEUTICS IN COM 35104E100   63,720 2,000 SH   SOLE   63,720 0 0
89BIO INC COM 282559103   35,618 3,060 SH   SOLE   35,618 0 0
99 ACQUISITION GROUP INC UNIT 99/99/9999 65445K200   78,675 7,500 SH   SOLE   78,675 0 0
AB ACTIVE ETFS INC ULTRA SHORT INCM 00039J103   505,200 10,000 SH   SOLE   505,200 0 0
ABBOTT LABS COM 002824100   159,124 1,400 SH   SOLE   159,124 0 0
ABIVAX SA SPONSORED ADS 00370M103   214,500 15,000 SH   SOLE   214,500 0 0
ABSCI CORPORATION COM 00091E109   3,334,069 586,984 SH   SOLE   3,334,069 0 0
ACADIA PHARMACEUTICALS INC COM 004225108   9,245 500 SH   SOLE   9,245 0 0
ACASTI PHARMA INC CL A 00430K865   744,530 217,381 SH   SOLE   744,530 0 0
ACELYRIN INC COM 00445A100   101,392 15,021 SH   SOLE   101,392 0 0
ACHIEVE LIFE SCIENCES INC COM 004468500   3,976,875 875,000 SH   SOLE   3,976,875 0 0
ACTINIUM PHARMACEUTICALS INC COM 00507W206   783,000 100,000 SH   SOLE   783,000 0 0
ADDEX THERAPEUTICS LTD SPONSORED ADS 00654J206   4,992 390 SH   SOLE   4,992 0 0
ADICET BIO INC COM 007002108   73,388 31,229 SH   SOLE   73,388 0 0
ADVERUM BIOTECHNOLOGIES INC COM NEW 00773U207   39,592 2,800 SH   SOLE   39,592 0 0
AEROVATE THERAPEUTICS INC COM 008064107   470,163 15,900 SH   SOLE   470,163 0 0
AI TRANSN ACQUISITION CORP UNIT 99/99/9999 G01490138   78,150 7,500 SH   SOLE   78,150 0 0
AIMFINITY INVESTMENT CORP I *W EXP 99/99/999 G0135E126   234 18,000 SH   SOLE   234 0 0
AKEBIA THERAPEUTICS INC COM 00972D105   17,751 9,700 SH Put SOLE   17,751 0 0
AKERO THERAPEUTICS INC COM 00973Y108   45,645 1,807 SH   SOLE   45,645 0 0
ALECTOR INC COM 014442107   316,050 52,500 SH   SOLE   316,050 0 0
ALGONQUIN PWR UTILS CORP COM 015857105   233,840 37,000 SH   SOLE   233,840 0 0
ALKERMES PLC SHS G01767105   4,239,162 156,600 SH   SOLE   4,239,162 0 0
ALNYLAM PHARMACEUTICALS INC COM 02043Q107   26,922,670 180,145 SH   SOLE   26,922,670 0 0
ALNYLAM PHARMACEUTICALS INC COM 02043Q107   1,673,840 11,200 SH Call SOLE   1,673,840 0 0
ALNYLAM PHARMACEUTICALS INC COM 02043Q107   35,031,080 234,400 SH Put SOLE   35,031,080 0 0
ALPHABET INC CAP STK CL A 02079K305   301,860 2,000 SH   SOLE   301,860 0 0
ALTRIA GROUP INC COM 02209S103   87,240 2,000 SH   SOLE   87,240 0 0
AMPHASTAR PHARMACEUTICALS IN COM 03209R103   30,737 700 SH   SOLE   30,737 0 0
AMPLIFY ENERGY CORP NEW COM 03212B103   46,805 7,081 SH   SOLE   46,805 0 0
AMYLYX PHARMACEUTICALS INC COM 03237H101   110,357 38,858 SH   SOLE   110,357 0 0
AMYLYX PHARMACEUTICALS INC COM 03237H101   210,444 74,100 SH Call SOLE   210,444 0 0
AMYLYX PHARMACEUTICALS INC COM 03237H101   90,312 31,800 SH Put SOLE   90,312 0 0
ANAPTYSBIO INC COM 032724106   22,520 1,000 SH   SOLE   22,520 0 0
ANAPTYSBIO INC COM 032724106   45,040 2,000 SH Call SOLE   45,040 0 0
ANGIODYNAMICS INC COM 03475V101   900,235 153,362 SH   SOLE   900,235 0 0
APELLIS PHARMACEUTICALS INC COM 03753U106   1,510,646 25,700 SH   SOLE   1,510,646 0 0
APOGEE THERAPEUTICS INC COM 03770N101   398,700 6,000 SH   SOLE   398,700 0 0
APPLIED THERAPEUTICS INC COM 03828A101   3,104,798 456,588 SH   SOLE   3,104,798 0 0
APPLIED THERAPEUTICS INC COM 03828A101   204,680 30,100 SH Put SOLE   204,680 0 0
ARBUTUS BIOPHARMA CORP COM 03879J100   5,351,392 2,074,183 SH   SOLE   5,351,392 0 0
ARCUTIS BIOTHERAPEUTICS INC COM 03969K108   42,157 4,254 SH   SOLE   42,157 0 0
ARROWHEAD PHARMACEUTICALS IN COM 04280A100   17,160 600 SH   SOLE   17,160 0 0
ARVINAS INC COM 04335A105   1,081,536 26,200 SH   SOLE   1,081,536 0 0
ARYA SCIENCES ACQU CORP IV CL A G31659108   459,644 40,930 SH   SOLE   459,644 0 0
ASCENDIS PHARMA A/S SPONSORED ADR 04351P101   7,344,443 48,584 SH   SOLE   7,344,443 0 0
ASLAN PHARMACEUTICALS LTD SPON ADS NEW 04522R200   36,539 59,393 SH   SOLE   36,539 0 0
ASTRAZENECA PLC SPONSORED ADR 046353108   13,550 200 SH   SOLE   13,550 0 0
ASTRIA THERAPEUTICS INC COM 04635X102   65,477 4,652 SH   SOLE   65,477 0 0
AURINIA PHARMACEUTICALS INC COM 05156V102   10,020 2,000 SH   SOLE   10,020 0 0
AVALO THERAPEUTICS INC COM NEW 05338F306   130,500 6,000 SH   SOLE   130,500 0 0
AVROBIO INC COM 05455M100   5,062,217 3,954,857 SH   SOLE   5,062,217 0 0
BAUSCH HEALTH COS INC COM 071734107   63,660 6,000 SH Call SOLE   63,660 0 0
BAUSCH PLUS LOMB CORP COMMON SHARES 071705107   91,690 5,300 SH   SOLE   91,690 0 0
BEIGENE LTD SPONSORED ADR 07725L102   4,927,067 31,505 SH   SOLE   4,927,067 0 0
BEYOND AIR INC COM 08862L103   2,096,387 1,204,820 SH   SOLE   2,096,387 0 0
BEYOND MEAT INC COM 08862E109   4,778 577 SH   SOLE   4,778 0 0
BICYCLE THERAPEUTICS PLC SPONSORED ADS 088786108   359,307 14,430 SH   SOLE   359,307 0 0
BIOHAVEN LTD COM G1110E107   10,938 200 SH   SOLE   10,938 0 0
BIOHAVEN LTD COM G1110E107   109,380 2,000 SH Call SOLE   109,380 0 0
BLACK HAWK ACQUISITION CORP UNIT 99/99/9999 G1148A127   152,250 15,000 SH   SOLE   152,250 0 0
BLUEBIRD BIO INC COM 09609G100   6,400 5,000 SH   SOLE   6,400 0 0
BOLT BIOTHERAPEUTICS INC COM 097702104   7,000 5,000 SH   SOLE   7,000 0 0
BRIDGEBIO PHARMA INC COM 10806X102   16,999,940 549,804 SH   SOLE   16,999,940 0 0
BRIDGEBIO PHARMA INC COM 10806X102   37,104 1,200 SH Put SOLE   37,104 0 0
CABALETTA BIO INC COM 12674W109   151,834 8,900 SH   SOLE   151,834 0 0
CALCIMEDICA INC COM NEW 38942Q202   3,249 781 SH   SOLE   3,249 0 0
CELLECTAR BIOSCIENCES INC COM NEW 15117F807   2,557,313 642,541 SH   SOLE   2,557,313 0 0
CENTESSA PHARMACEUTICALS PLC SPONSORED ADS 152309100   2,337,473 206,856 SH   SOLE   2,337,473 0 0
CEREVEL THERAPEUTICS HLDNG I COM 15678U128   1,025,428 24,259 SH   SOLE   1,025,428 0 0
CEREVEL THERAPEUTICS HLDNG I COM 15678U128   2,121,954 50,200 SH Put SOLE   2,121,954 0 0
CETUS CAP ACQUISITION CORP RIGHT 03/31/2024 15719Y121   605 4,999 SH   SOLE   605 0 0
CETUS CAP ACQUISITION CORP *W EXP 01/31/202 15719Y113   95 5,000 SH   SOLE   95 0 0
CG ONCOLOGY INC COM 156944100   89,995 2,050 SH   SOLE   89,995 0 0
COGENT COMMUNICATIONS HLDGS COM NEW 19239V302   261,320 4,000 SH   SOLE   261,320 0 0
COMPASS THERAPEUTICS INC COM 20454B104   20,208 10,206 SH   SOLE   20,208 0 0
CONTEXT THERAPEUTICS INC COM 21077P108   284,189 205,934 SH   SOLE   284,189 0 0
CORBUS PHARMACEUTICALS HLDGS COM NEW 21833P301   627,840 16,000 SH   SOLE   627,840 0 0
CORTEVA INC COM 22052L104   2,156,858 37,400 SH   SOLE   2,156,858 0 0
CYTOKINETICS INC COM NEW 23282W605   22,400,846 319,510 SH   SOLE   22,400,846 0 0
CYTOKINETICS INC COM NEW 23282W605   175,275 2,500 SH Call SOLE   175,275 0 0
CYTOMX THERAPEUTICS INC COM 23284F105   337,900 155,000 SH   SOLE   337,900 0 0
DELCATH SYS INC COM NEW 24661P807   1,044,501 218,973 SH   SOLE   1,044,501 0 0
DENALI THERAPEUTICS INC COM 24823R105   41,040 2,000 SH   SOLE   41,040 0 0
DESIGN THERAPEUTICS INC COM 25056L103   29,016 7,200 SH   SOLE   29,016 0 0
DISC MEDICINE INC COM 254604101   55,785 896 SH   SOLE   55,785 0 0
DYNE THERAPEUTICS INC COM 26818M108   8,432 297 SH   SOLE   8,432 0 0
EA SERIES TRUST ALPHA ARCH 1-3 02072L565   33,867,055 318,120 SH   SOLE   33,867,055 0 0
ECD AUTOMOTIVE DESIGN INC *W EXP 12/12/202 27877D112   818 32,596 SH   SOLE   818 0 0
EDGEWISE THERAPEUTICS INC COM 28036F105   3,299,817 180,911 SH   SOLE   3,299,817 0 0
ELEVATION ONCOLOGY INC COM 28623U101   44,267 8,629 SH   SOLE   44,267 0 0
ELI LILLY & CO COM 532457108   1,450,895 1,865 SH   SOLE   1,450,895 0 0
EMBRACE CHANGE ACQUISITN COR RIGHT 10/25/2026 G3034H141   2,524 18,000 SH   SOLE   2,524 0 0
EMBRACE CHANGE ACQUISITN COR *W EXP 10/25/202 G3034H125   407 18,000 SH   SOLE   407 0 0
ENDEAVOR GROUP HLDGS INC CL A COM 29260Y109   3,994,582 155,250 SH   SOLE   3,994,582 0 0
ENVVENO MEDICAL CORPORATION COM 29415J106   1,097,400 201,728 SH   SOLE   1,097,400 0 0
EQUILLIUM INC COM 29446K106   459,170 198,775 SH   SOLE   459,170 0 0
EQUILLIUM INC COM 29446K106   23,100 10,000 SH Call SOLE   23,100 0 0
EVOTEC AG SPONSORED ADS 30050E105   60,291 7,700 SH   SOLE   60,291 0 0
EXACT SCIENCES CORP COM 30063P105   117,402 1,700 SH   SOLE   117,402 0 0
FEUTUNE LIGHT ACQUISITION CO RIGHT 06/01/2029 31561T128   1,276 15,000 SH   SOLE   1,276 0 0
FEUTUNE LIGHT ACQUISITION CO CL A COM 31561T102   163,050 15,000 SH   SOLE   163,050 0 0
FEUTUNE LIGHT ACQUISITION CO *W EXP 06/01/202 31561T110   510 15,000 SH   SOLE   510 0 0
FIBROGEN INC COM 31572Q808   50,172 21,350 SH   SOLE   50,172 0 0
FORTE BIOSCIENCES INC COM 34962G109   118,709 170,510 SH   SOLE   118,709 0 0
FOUR LEAF ACQUISITION CORP COM CL A 35088F107   107,200 10,000 SH   SOLE   107,200 0 0
FOUR LEAF ACQUISITION CORP *W EXP 03/15/202 35088F115   390 9,487 SH   SOLE   390 0 0
FULCRUM THERAPEUTICS INC COM 359616109   3,207,948 339,825 SH   SOLE   3,207,948 0 0
FUSION PHARMACEUTICALS INC COM 36118A100   3,777,904 177,200 SH   SOLE   3,777,904 0 0
FUTURETECH II ACQUISITION CO *W EXP 08/18/202 36119D111   1,182 30,000 SH   SOLE   1,182 0 0
GERON CORP COM 374163103   4,274 1,295 SH   SOLE   4,274 0 0
GH RESEARCH PLC ORDINARY SHARES G3855L106   134,135 12,583 SH   SOLE   134,135 0 0
GLOBAL STAR ACQUISITION INC RIGHT 06/21/2024 37962G128   10,668 118,400 SH   SOLE   10,668 0 0
GLOBAL STAR ACQUISITION INC CLASS A COM 37962G102   856,800 80,000 SH   SOLE   856,800 0 0
GLOBAL STAR ACQUISITION INC *W EXP 07/15/202 37962G110   1,956 120,000 SH   SOLE   1,956 0 0
GLYCOMIMETICS INC COM 38000Q102   417,300 139,100 SH Put SOLE   417,300 0 0
GOSSAMER BIO INC COM 38341P102   864,501 732,628 SH   SOLE   864,501 0 0
GREENLIGHT CAPITAL RE LTD CLASS A G4095J109   166,911 13,385 SH   SOLE   166,911 0 0
GUARDANT HEALTH INC COM 40131M109   350,710 17,000 SH   SOLE   350,710 0 0
GUARDANT HEALTH INC COM 40131M109   2,063,000 100,000 SH Call SOLE   2,063,000 0 0
HELIX ACQUISITION CORP II CL A ORD SHS G4444H101   4,196,400 403,500 SH   SOLE   4,196,400 0 0
HOOKIPA PHARMA INC COM 43906K100   35,600 50,000 SH   SOLE   35,600 0 0
HOWARD HUGHES HOLDINGS INC COM 44267T102   72,620 1,000 SH   SOLE   72,620 0 0
IBIO INC CON NEW 451033708   2,192,400 600,000 SH   SOLE   2,192,400 0 0
ICHOR HOLDINGS SHS G4740B105   4,171 108 SH   SOLE   4,171 0 0
IGM BIOSCIENCES INC COM 449585108   38,600 4,000 SH   SOLE   38,600 0 0
IKENA ONCOLOGY INC COM 45175G108   49,700 35,000 SH   SOLE   49,700 0 0
IMMATICS N.V SHS N44445109   170,262 16,200 SH   SOLE   170,262 0 0
IMMUNOVANT INC COM 45258J102   1,963,253 60,763 SH   SOLE   1,963,253 0 0
INDIVIOR PLC ORD G4766E116   591,213 27,601 SH   SOLE   591,213 0 0
INSMED INC COM PAR $.01 457669307   46,121 1,700 SH Put SOLE   46,121 0 0
INTELLIGENT BIO SOLUTIONS IN COM 36151G600   456,815 108,250 SH   SOLE   456,815 0 0
INVESCO QQQ TR UNIT SER 1 46090E103   4,440,100 10,000 SH Put SOLE   4,440,100 0 0
IONIS PHARMACEUTICALS INC COM 462222100   125,715 2,900 SH   SOLE   125,715 0 0
IOVANCE BIOTHERAPEUTICS INC COM 462260100   74,100 5,000 SH   SOLE   74,100 0 0
IRON HORSE ACQUISITIONS CORP UNIT 10/15/2028 462837204   254,750 25,000 SH   SOLE   254,750 0 0
ISHARES TR SHORT TREAS BD 464288679   2,708,230 24,500 SH   SOLE   2,708,230 0 0
ISHARES TR 20 YR TR BD ETF 464287432   189,240 2,000 SH   SOLE   189,240 0 0
J P MORGAN EXCHANGE TRADED F ULTRA SHRT INC 46641Q837   2,724,300 54,000 SH   SOLE   2,724,300 0 0
JANUX THERAPEUTICS INC COM 47103J105   527,100 14,000 SH   SOLE   527,100 0 0
JASPER THERAPEUTICS INC COM NEW 471871202   70,640 2,406 SH   SOLE   70,640 0 0
JD.COM INC SPON ADR CL A 47215P106   109,560 4,000 SH   SOLE   109,560 0 0
JVSPAC ACQUISITION CORP UNIT 03/11/2024 G5212E139   309,000 30,000 SH   SOLE   309,000 0 0
KALVISTA PHARMACEUTICALS INC COM 483497103   118,600 10,000 SH   SOLE   118,600 0 0
KARYOPHARM THERAPEUTICS INC COM 48576U106   2,233 1,479 SH   SOLE   2,233 0 0
KEEN VISION ACQUISITION CORP UNIT 99/99/9999 G52443101   788,250 75,000 SH   SOLE   788,250 0 0
KENSINGTON CAPITAL ACQUISITI SHS CL A G5251K103   97,560 9,000 SH   SOLE   97,560 0 0
KEROS THERAPEUTICS INC COM 492327101   22,391,687 338,243 SH   SOLE   22,391,687 0 0
KEZAR LIFE SCIENCES INC COM 49372L100   213,339 236,623 SH   SOLE   213,339 0 0
KINIKSA PHARMACEUTICALS LTD COM CL A G5269C101   1,177,881 59,700 SH   SOLE   1,177,881 0 0
KIORA PHARMACEUTICALS INC COM NEW 49721T309   776,600 1,100,000 SH   SOLE   776,600 0 0
KOHLS CORP COM 500255104   58,300 2,000 SH   SOLE   58,300 0 0
KRANESHARES TRUST CSI CHI INTERNET 500767306   52,500 2,000 SH   SOLE   52,500 0 0
KRYSTAL BIOTECH INC COM 501147102   53,379 300 SH   SOLE   53,379 0 0
KYMERA THERAPEUTICS INC COM 501575104   643,200 16,000 SH   SOLE   643,200 0 0
LANTHEUS HLDGS INC COM 516544103   62,240 1,000 SH   SOLE   62,240 0 0
LEXARIA BIOSCIENCE CORP COM NEW 52886N406   96,652 26,626 SH   SOLE   96,652 0 0
LIGAND PHARMACEUTICALS INC COM NEW 53220K504   1,959,080 26,800 SH   SOLE   1,959,080 0 0
LIQUIDIA CORPORATION COM NEW 53635D202   29,500 2,000 SH   SOLE   29,500 0 0
LONGBOARD PHARMACEUTICALS IN COM 54300N103   98,928 4,580 SH   SOLE   98,928 0 0
MAGNACHIP SEMICONDUCTOR CORP COM 55933J203   39,060 7,000 SH   SOLE   39,060 0 0
MARAVAI LIFESCIENCES HLDGS I COM CL A 56600D107   8,670 1,000 SH   SOLE   8,670 0 0
MASIMO CORP COM 574795100   5,580 38 SH   SOLE   5,580 0 0
MCKESSON CORP COM 58155Q103   134,212 250 SH   SOLE   134,212 0 0
MERCK & CO INC COM 58933Y105   39,585 300 SH   SOLE   39,585 0 0
MERRIMACK PHARMACEUTICALS IN COM NEW 590328209   13,327,710 902,350 SH   SOLE   13,327,710 0 0
MILESTONE PHARMACEUTICALS IN COM 59935V107   362,403 202,460 SH   SOLE   362,403 0 0
MINERALYS THERAPEUTICS INC COM 603170101   309,840 24,000 SH   SOLE   309,840 0 0
MITEK SYS INC COM NEW 606710200   78,960 5,600 SH   SOLE   78,960 0 0
MOONLAKE IMMUNOTHERAPEUTICS CLASS A ORD 61559X104   150,690 3,000 SH   SOLE   150,690 0 0
MORPHIC HLDG INC COM 61775R105   693,475 19,701 SH   SOLE   693,475 0 0
NCR ATLEOS CORPORATION COM SHS 63001N106   19,750 1,000 SH   SOLE   19,750 0 0
NCR VOYIX CORPORATION COM 62886E108   25,260 2,000 SH   SOLE   25,260 0 0
NEUROGENE INC COM 64135M105   33,645 661 SH   SOLE   33,645 0 0
NEXTCURE INC COM 65343E108   95,921 43,014 SH   SOLE   95,921 0 0
NGM BIOPHARMACEUTICALS INC COM 62921N105   1,298,364 816,581 SH   SOLE   1,298,364 0 0
NOVO-NORDISK A S ADR 670100205   12,840 100 SH   SOLE   12,840 0 0
NURIX THERAPEUTICS INC COM 67080M103   523,438 35,608 SH   SOLE   523,438 0 0
NUVEI CORPORATION SUB VTG SHS 67079A102   158,100 5,000 SH   SOLE   158,100 0 0
OAK WOODS ACQUISITION CORP CL A 67190B104   322,500 30,000 SH   SOLE   322,500 0 0
OAK WOODS ACQUISITION CORP RIGHT 03/23/2028 67190B120   6,000 30,000 SH   SOLE   6,000 0 0
OAK WOODS ACQUISITION CORP *W EXP 99/99/999 67190B112   600 30,000 SH   SOLE   600 0 0
OMNIAB INC COM 68218J103   2,447,049 451,485 SH   SOLE   2,447,049 0 0
ONCTERNAL THERAPEUTICS INC COM NEW 68236P206   22,248 2,472 SH   SOLE   22,248 0 0
OPTION CARE HEALTH INC COM NEW 68404L201   234,780 7,000 SH   SOLE   234,780 0 0
ORGANON & CO COMMON STOCK 68622V106   112,800 6,000 SH   SOLE   112,800 0 0
OVID THERAPEUTICS INC COM 690469101   50,160 16,446 SH   SOLE   50,160 0 0
PASITHEA THERAPEUTICS CORP COM NEW 70261F202   200,804 27,696 SH   SOLE   200,804 0 0
PERRIGO CO PLC SHS G97822103   25,752 800 SH   SOLE   25,752 0 0
PERSPECTIVE THERAPEUTICS INC COM 46489V104   805,303 676,725 SH   SOLE   805,303 0 0
PFIZER INC COM 717081103   2,950,990 106,342 SH   SOLE   2,950,990 0 0
PGIM ETF TR PGIM ULTRA SH BD 69344A107   497,000 10,000 SH   SOLE   497,000 0 0
PHARVARIS N V COM N69605108   46,220 2,000 SH   SOLE   46,220 0 0
PIMCO ETF TR 25YR+ ZERO U S 72201R882   237,750 3,000 SH   SOLE   237,750 0 0
PMV PHARMACEUTICALS INC COM 69353Y103   17,000 10,000 SH   SOLE   17,000 0 0
PONO CAP TWO INC *W EXP 99/99/999 73245B115   693 19,800 SH   SOLE   693 0 0
PROTAGONIST THERAPEUTICS INC COM 74366E102   22,728,999 785,655 SH   SOLE   22,728,999 0 0
PROTARA THERAPEUTICS INC COM STK 74365U107   8,020 2,000 SH   SOLE   8,020 0 0
PROTHENA CORP PLC SHS G72800108   148,323 5,988 SH   SOLE   148,323 0 0
PYXIS ONCOLOGY INC COMMON STOCK 747324101   42,600 10,000 SH   SOLE   42,600 0 0
Q32 BIO INC COM 746964105   3,196,142 187,567 SH   SOLE   3,196,142 0 0
QUINCE THERAPEUTICS INC COM 22053A107   28,439 26,829 SH   SOLE   28,439 0 0
RALLYBIO CORP COM 75120L100   33,193 17,942 SH   SOLE   33,193 0 0
RAPT THERAPEUTICS INC COM 75382E109   67,350 7,500 SH Put SOLE   67,350 0 0
REGENERON PHARMACEUTICALS COM 75886F107   2,213,727 2,300 SH   SOLE   2,213,727 0 0
REGENXBIO INC COM 75901B107   52,675 2,500 SH   SOLE   52,675 0 0
RELMADA THERAPEUTICS INC COM 75955J402   2,795 601 SH   SOLE   2,795 0 0
RHYTHM PHARMACEUTICALS INC COM 76243J105   537,292 12,400 SH   SOLE   537,292 0 0
ROIVANT SCIENCES LTD SHS G76279101   29,426,310 2,791,870 SH   SOLE   29,426,310 0 0
ROYALTY PHARMA PLC SHS CLASS A G7709Q104   21,905,911 721,301 SH   SOLE   21,905,911 0 0
SANOFI SPONSORED ADR 80105N105   267,300 5,500 SH   SOLE   267,300 0 0
SAREPTA THERAPEUTICS INC COM 803607100   4,026,853 31,105 SH   SOLE   4,026,853 0 0
SAREPTA THERAPEUTICS INC COM 803607100   155,352 1,200 SH Call SOLE   155,352 0 0
SAVARA INC COM 805111101   27,888 5,600 SH   SOLE   27,888 0 0
SCHRODINGER INC COM 80810D103   1,716,822 63,586 SH   SOLE   1,716,822 0 0
SCREAMING EAGLE ACQUISITN CO CLASS A ORD SHS G79407105   321,000 30,000 SH   SOLE   321,000 0 0
SILENCE THERAPEUTICS PLC ADS 82686Q101   865,944 40,090 SH   SOLE   865,944 0 0
SOLID BIOSCIENCES INC COM NEW 83422E204   2,706,677 203,204 SH   SOLE   2,706,677 0 0
SPDR S&P 500 ETF TR TR UNIT 78462F103   27,199,640 52,000 SH Put SOLE   27,199,640 0 0
SPDR SER TR BLOOMBERG 1-3 MO 78468R663   2,983,500 32,500 SH   SOLE   2,983,500 0 0
SPERO THERAPEUTICS INC COM 84833T103   1,594,318 926,929 SH   SOLE   1,594,318 0 0
SPRUCE BIOSCIENCES INC COM 85209E109   287,023 365,216 SH   SOLE   287,023 0 0
SPYRE THERAPEUTICS INC COM NEW 00773J202   1,877,535 49,500 SH   SOLE   1,877,535 0 0
SSGA ACTIVE ETF TR ULT SHT TRM BD 78467V707   1,931,202 47,684 SH   SOLE   1,931,202 0 0
STEEL PARTNERS HLDGS L P LTD PRTRSHIP U 85814R107   13,521 341 SH   SOLE   13,521 0 0
STEVANATO GROUP S P A ORD SHS T9224W109   497,550 15,500 SH   SOLE   497,550 0 0
STOKE THERAPEUTICS INC COM 86150R107   39,150 2,900 SH   SOLE   39,150 0 0
STRUCTURE THERAPEUTICS INC SPONSORED ADS 86366E106   107,150 2,500 SH   SOLE   107,150 0 0
STRUCTURE THERAPEUTICS INC SPONSORED ADS 86366E106   34,288 800 SH Call SOLE   34,288 0 0
SURROZEN INC COM NEW 86889P208   7,070 450 SH   SOLE   7,070 0 0
TALIS BIOMEDICAL CORP COM NEW 87424L207   2,625 300 SH   SOLE   2,625 0 0
TAYSHA GENE THERAPIES INC COM SHS 877619106   124,845 43,500 SH   SOLE   124,845 0 0
TERNS PHARMACEUTICALS INC COM 880881107   32,800 5,000 SH   SOLE   32,800 0 0
TEVA PHARMACEUTICAL INDS LTD SPONSORED ADS 881624209   1,433,943 101,626 SH   SOLE   1,433,943 0 0
TG THERAPEUTICS INC COM 88322Q108   66,331 4,361 SH   SOLE   66,331 0 0
THERAPEUTICSMD INC COM NEW 88338N206   623,246 272,160 SH   SOLE   623,246 0 0
TMT ACQUISITION CORP RIGHT 03/27/2028 G89229135   8,982 49,900 SH   SOLE   8,982 0 0
TMT ACQUISITION CORP SHS G89229119   534,500 50,000 SH   SOLE   534,500 0 0
TOURMALINE BIO INC COM 89157D105   264,724 11,560 SH   SOLE   264,724 0 0
TRAVERE THERAPEUTICS INC COM 89422G107   771 100 SH   SOLE   771 0 0
TRUMP MEDIA & TECHNOLOGY GRO COM 25400Q105   278,820 4,500 SH Call SOLE   278,820 0 0
TYRA BIOSCIENCES INC COM 90240B106   464,120 28,300 SH   SOLE   464,120 0 0
ULTRA CLEAN HLDGS INC COM 90385V107   45,940 1,000 SH   SOLE   45,940 0 0
UNIQURE NV SHS N90064101   1,522,820 292,850 SH   SOLE   1,522,820 0 0
VANECK ETF TRUST GOLD MINERS ETF 92189F106   63,240 2,000 SH   SOLE   63,240 0 0
VANGUARD BD INDEX FDS VANGUARD ULTRA 92203C303   2,735,457 55,206 SH   SOLE   2,735,457 0 0
VAXCYTE INC COM 92243G108   136,620 2,000 SH   SOLE   136,620 0 0
VENTYX BIOSCIENCES INC COM 92332V107   27,500 5,000 SH   SOLE   27,500 0 0
VERU INC COM 92536C103   235,284 336,072 SH   SOLE   235,284 0 0
VIKING THERAPEUTICS INC COM 92686J106   1,180,882 14,401 SH   SOLE   1,180,882 0 0
VIRIDIAN THERAPEUTICS INC COM 92790C104   44,650 2,550 SH   SOLE   44,650 0 0
VISTAGEN THERAPEUTICS INC COM 92840H400   474,873 89,938 SH   SOLE   474,873 0 0
VOYAGER THERAPEUTICS INC COM 92915B106   852,182 91,534 SH   SOLE   852,182 0 0
VYNE THERAPEUTICS INC COM 92941V308   337,979 110,091 SH   SOLE   337,979 0 0
WAVE LIFE SCIENCES LTD SHS Y95308105   185,100 30,000 SH   SOLE   185,100 0 0
WEST PHARMACEUTICAL SVSC INC COM 955306105   593,565 1,500 SH   SOLE   593,565 0 0
WISDOMTREE TR FLOATNG RAT TREA 97717Y527   2,665,370 53,000 SH   SOLE   2,665,370 0 0
XERIS BIOPHARMA HOLDINGS INC COM 98422E103   11,379 5,149 SH   SOLE   11,379 0 0
ZAI LAB LTD ADR 98887Q104   352,440 22,000 SH   SOLE   352,440 0 0
ZYMEWORKS INC COM 98985Y108   19,988 1,900 SH   SOLE   19,988 0 0