The Securities and Exchange Commission has not necessarily reviewed the information in this filing and has not determined if it is accurate and complete.
The reader should not assume that the information is accurate and complete.

UNITED STATES SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549
FORM 13F

FORM 13F INFORMATION TABLE
OMB APPROVAL
OMB Number: 3235-0006
Estimated average burden
hours per response: 23.8
COLUMN 1 COLUMN 2 COLUMN 3 COLUMN 4 COLUMN 5 COLUMN 6 COLUMN 7 COLUMN 8
VALUE SHRS OR SH/ PUT/ INVESTMENT OTHER VOTING AUTHORITY
NAME OF ISSUER TITLE OF CLASS CUSIP FIGI (to the nearest dollar) PRN AMT PRN CALL DISCRETION MANAGER SOLE SHARED NONE
PDD Holdings Inc ADR 722304102   289,374 3,812,569 SH   DFND   3,812,569 0 0
Tencent Music Entertainment Gr ADR 88034P109   77,222 9,326,423 SH   DFND   9,326,423 0 0
Sea Ltd ADR 81141R100   65,470 756,446 SH   SOLE   756,446 0 0
KE Holdings Inc ADR 482497104   60,691 3,221,430 SH   DFND   3,221,430 0 0
Microsoft Corp Common Stock 594918104   59,443 206,183 SH   DFND   206,183 0 0
STAAR Surgical Co Common Stock 852312305   57,702 902,296 SH   SOLE   902,296 0 0
Taiwan Semiconductor Manufactu ADR 874039100   50,696 545,000 SH   SOLE   545,000 0 0
Full Truck Alliance Co Ltd ADR 35969L108   43,204 5,677,229 SH   SOLE   5,677,229 0 0
Apple Inc Common Stock 037833100   41,028 248,804 SH   SOLE   248,804 0 0
Vipshop Holdings Ltd ADR 92763W103   39,076 2,574,203 SH   DFND   2,574,203 0 0
Kanzhun Ltd ADR 48553T106   37,249 1,957,368 SH   DFND   1,957,368 0 0
Grab Holdings Ltd Common Stock G4124C109   35,909 11,930,000 SH   SOLE   11,930,000 0 0
Advanced Micro Devices Inc Common Stock 007903107   33,640 343,232 SH   SOLE   343,232 0 0
ASML Holding NV NY Reg Shrs N07059210   28,693 42,152 SH   SOLE   42,152 0 0
Yum China Holdings Inc Common Stock 98850P109   24,859 392,164 SH   SOLE   392,164 0 0
TAL Education Group ADR 874080104   19,681 3,070,365 SH   DFND   3,070,365 0 0
Trip.com Group Ltd ADR 89677Q107   19,259 511,252 SH   SOLE   511,252 0 0
iQIYI Inc ADR 46267X108   17,918 2,461,256 SH   DFND   2,461,256 0 0
NVIDIA Corp Common Stock 67066G104   17,899 64,437 SH   DFND   64,437 0 0
Autohome Inc ADR 05278C107   15,385 459,671 SH   DFND   459,671 0 0
360 DigiTech Inc ADR 88557W101   14,558 750,390 SH   DFND   750,390 0 0
NIO Inc ADR 62914V106   13,493 1,283,849 SH   SOLE   1,283,849 0 0
Marvell Technology Inc Common Stock 573874104   11,704 270,289 SH   SOLE   270,289 0 0
Weibo Corp ADR 948596101   11,364 566,530 SH   DFND   566,530 0 0
ZTO Express Cayman Inc ADR 98980A105   11,350 396,021 SH   SOLE   396,021 0 0
KLA Corp Common Stock 482480100   10,909 27,329 SH   SOLE   27,329 0 0
Lufax Holding Ltd ADR 54975P102   10,897 5,341,418 SH   DFND   5,341,418 0 0
JOYY Inc ADR 46591M109   9,359 300,178 SH   DFND   300,178 0 0
Amazon.com Inc Common Stock 023135106   8,981 86,954 SH   SOLE   86,954 0 0
H World Group Ltd ADR 44332N106   8,864 180,971 SH   SOLE   180,971 0 0
QUALCOMM Inc Common Stock 747525103   8,496 66,594 SH   SOLE   66,594 0 0
Tesla Inc Common Stock 88160R101   7,246 34,929 SH   SOLE   34,929 0 0
Alphabet Inc Common Stock 02079K305   5,474 52,769 SH   SOLE   52,769 0 0
Broadcom Inc Common Stock 11135F101   5,276 8,224 SH   SOLE   8,224 0 0
Alphabet Inc Common Stock 02079K107   5,267 50,643 SH   SOLE   50,643 0 0
Meta Platforms Inc Common Stock 30303M102   5,080 23,969 SH   SOLE   23,969 0 0
Cisco Systems Inc Common Stock 17275R102   4,224 80,808 SH   SOLE   80,808 0 0
iShares MSCI Global Gold Miner ETP 46434G855   4,023 159,850 SH   SOLE   159,850 0 0
Adobe Inc Common Stock 00724F101   3,476 9,019 SH   SOLE   9,019 0 0
iShares Gold Trust ETP 464285204   3,453 92,405 SH   SOLE   92,405 0 0
SPDR Gold MiniShares Trust ETP 98149E303   3,451 88,235 SH   SOLE   88,235 0 0
Texas Instruments Inc Common Stock 882508104   3,320 17,850 SH   SOLE   17,850 0 0
Alibaba Group Holding Ltd ADR 01609W102   3,232 31,628 SH   SOLE   31,628 0 0
VanEck Gold Miners ETF/USA ETP 92189F106   2,828 87,434 SH   SOLE   87,434 0 0
Zai Lab Ltd ADR 98887Q104   2,747 82,587 SH   SOLE   82,587 0 0
PepsiCo Inc Common Stock 713448108   2,704 14,832 SH   SOLE   14,832 0 0
Intel Corp Common Stock 458140100   2,662 81,487 SH   SOLE   81,487 0 0
Legend Biotech Corp ADR 52490G102   2,648 54,913 SH   SOLE   54,913 0 0
Daqo New Energy Corp ADR 23703Q203   2,633 56,219 SH   SOLE   56,219 0 0
Micron Technology Inc Common Stock 595112103   2,631 43,610 SH   SOLE   43,610 0 0
SPDR Gold Shares ETP 78463V107   2,604 14,210 SH   SOLE   14,210 0 0
Intuit Inc Common Stock 461202103   2,466 5,532 SH   SOLE   5,532 0 0
Costco Wholesale Corp Common Stock 22160K105   2,375 4,779 SH   SOLE   4,779 0 0
Estee Lauder Cos Inc/The Common Stock 518439104   2,216 8,993 SH   SOLE   8,993 0 0
Salesforce Inc Common Stock 79466L302   2,156 10,792 SH   SOLE   10,792 0 0
Applied Materials Inc Common Stock 038222105   2,042 16,626 SH   SOLE   16,626 0 0
Analog Devices Inc Common Stock 032654105   1,968 9,977 SH   SOLE   9,977 0 0
NIKE Inc Common Stock 654106103   1,955 15,943 SH   SOLE   15,943 0 0
Accenture PLC Common Stock G1151C101   1,942 6,796 SH   SOLE   6,796 0 0
Amgen Inc Common Stock 031162100   1,902 7,868 SH   SOLE   7,868 0 0
T-Mobile US Inc Common Stock 872590104   1,733 11,964 SH   SOLE   11,964 0 0
Comcast Corp Common Stock 20030N101   1,717 45,301 SH   SOLE   45,301 0 0
Netflix Inc Common Stock 64110L106   1,657 4,797 SH   SOLE   4,797 0 0
Marriott International Inc/MD Common Stock 571903202   1,654 9,963 SH   SOLE   9,963 0 0
Gilead Sciences Inc Common Stock 375558103   1,618 19,501 SH   SOLE   19,501 0 0
MINISO Group Holding Ltd ADR 66981J102   1,580 89,060 SH   SOLE   89,060 0 0
Oracle Corp Common Stock 68389X105   1,541 16,585 SH   SOLE   16,585 0 0
Regeneron Pharmaceuticals Inc Common Stock 75886F107   1,483 1,805 SH   SOLE   1,805 0 0
Lam Research Corp Common Stock 512807108   1,410 2,659 SH   SOLE   2,659 0 0
Vertex Pharmaceuticals Inc Common Stock 92532F100   1,402 4,450 SH   SOLE   4,450 0 0
Honeywell International Inc Common Stock 438516106   1,375 7,196 SH   SOLE   7,196 0 0
Starbucks Corp Common Stock 855244109   1,289 12,377 SH   SOLE   12,377 0 0
International Business Machine Common Stock 459200101   1,279 9,758 SH   SOLE   9,758 0 0
Synopsys Inc Common Stock 871607107   1,160 3,002 SH   SOLE   3,002 0 0
Moderna Inc Common Stock 60770K107   1,159 7,546 SH   SOLE   7,546 0 0
Cadence Design Systems Inc Common Stock 127387108   1,133 5,392 SH   SOLE   5,392 0 0
Dada Nexus Ltd ADR 23344D108   1,115 131,591 SH   SOLE   131,591 0 0
Booking Holdings Inc Common Stock 09857L108   1,085 409 SH   SOLE   409 0 0
Intuitive Surgical Inc Common Stock 46120E602   1,074 4,203 SH   SOLE   4,203 0 0
Lululemon Athletica Inc Common Stock 550021109   1,072 2,944 SH   SOLE   2,944 0 0
AbbVie Inc Common Stock 00287Y109   1,039 6,519 SH   SOLE   6,519 0 0
Berkshire Hathaway Inc Common Stock 084670702   1,036 3,356 SH   SOLE   3,356 0 0
Mondelez International Inc Common Stock 609207105   1,024 14,682 SH   SOLE   14,682 0 0
ServiceNow Inc Common Stock 81762P102   1,019 2,192 SH   SOLE   2,192 0 0
Automatic Data Processing Inc Common Stock 053015103   994 4,463 SH   SOLE   4,463 0 0
Biogen Inc Common Stock 09062X103   956 3,437 SH   SOLE   3,437 0 0
NXP Semiconductors NV Common Stock N6596X109   952 5,105 SH   SOLE   5,105 0 0
Fortinet Inc Common Stock 34959E109   929 13,981 SH   SOLE   13,981 0 0
PayPal Holdings Inc Common Stock 70450Y103   925 12,185 SH   SOLE   12,185 0 0
UnitedHealth Group Inc Common Stock 91324P102   922 1,950 SH   SOLE   1,950 0 0
Microchip Technology Inc Common Stock 595017104   904 10,791 SH   SOLE   10,791 0 0
Autodesk Inc Common Stock 052769106   885 4,251 SH   SOLE   4,251 0 0
iShares iBoxx $ Investment Gr ETP 464287242   866 7,900 SH   SOLE   7,900 0 0
Johnson & Johnson Common Stock 478160104   853 5,506 SH   SOLE   5,506 0 0
Exxon Mobil Corp Common Stock 30231G102   841 7,671 SH   SOLE   7,671 0 0
Seagen Inc Common Stock 81181C104   790 3,902 SH   SOLE   3,902 0 0
Fiserv Inc Common Stock 337738108   766 6,778 SH   SOLE   6,778 0 0
iShares Core S&P 500 ETF ETP 464287200   763 1,855 SH   SOLE   1,855 0 0
SPDR S&P 500 ETF Trust ETP 78462F103   763 1,863 SH   SOLE   1,863 0 0
Carnival Corp Common Stock 143658300   726 71,478 SH   SOLE   71,478 0 0
JPMorgan Chase & Co Common Stock 46625H100   712 5,464 SH   SOLE   5,464 0 0
Activision Blizzard Inc Common Stock 00507V109   711 8,312 SH   SOLE   8,312 0 0
Visa Inc Common Stock 92826C839   682 3,027 SH   SOLE   3,027 0 0
CSX Corp Common Stock 126408103   667 22,287 SH   SOLE   22,287 0 0
Procter & Gamble Co/The Common Stock 742718109   653 4,395 SH   SOLE   4,395 0 0
Cognizant Technology Solutions Common Stock 192446102   611 10,030 SH   SOLE   10,030 0 0
Eli Lilly & Co Common Stock 532457108   610 1,777 SH   SOLE   1,777 0 0
Merck & Co Inc Common Stock 58933Y105   597 5,616 SH   SOLE   5,616 0 0
MercadoLibre Inc Common Stock 58733R102   590 448 SH   SOLE   448 0 0
Dexcom Inc Common Stock 252131107   587 5,056 SH   SOLE   5,056 0 0
Monster Beverage Corp Common Stock 61174X109   579 10,713 SH   SOLE   10,713 0 0
ANSYS Inc Common Stock 03662Q105   571 1,717 SH   SOLE   1,717 0 0
Mastercard Inc Common Stock 57636Q104   571 1,572 SH   SOLE   1,572 0 0
O'Reilly Automotive Inc Common Stock 67103H107   567 668 SH   SOLE   668 0 0
Enphase Energy Inc Common Stock 29355A107   564 2,684 SH   SOLE   2,684 0 0
Home Depot Inc/The Common Stock 437076102   560 1,899 SH   SOLE   1,899 0 0
Charter Communications Inc Common Stock 16119P108   557 1,557 SH   SOLE   1,557 0 0
IDEXX Laboratories Inc Common Stock 45168D104   553 1,106 SH   SOLE   1,106 0 0
Chevron Corp Common Stock 166764100   541 3,314 SH   SOLE   3,314 0 0
Palo Alto Networks Inc Common Stock 697435105   538 2,696 SH   SOLE   2,696 0 0
Pfizer Inc Common Stock 717081103   526 12,904 SH   SOLE   12,904 0 0
Amphenol Corp Common Stock 032095101   524 6,417 SH   SOLE   6,417 0 0
Thermo Fisher Scientific Inc Common Stock 883556102   524 909 SH   SOLE   909 0 0
Motorola Solutions Inc Common Stock 620076307   516 1,805 SH   SOLE   1,805 0 0
Illumina Inc Common Stock 452327109   511 2,198 SH   SOLE   2,198 0 0
Viking Therapeutics Inc Common Stock 92686J106   511 30,676 SH   SOLE   30,676 0 0
Incyte Corp Common Stock 45337C102   509 7,047 SH   SOLE   7,047 0 0
Roper Technologies Inc Common Stock 776696106   505 1,145 SH   SOLE   1,145 0 0
American Electric Power Co Inc Common Stock 025537101   504 5,540 SH   SOLE   5,540 0 0
Keurig Dr Pepper Inc Common Stock 49271V100   498 14,109 SH   SOLE   14,109 0 0
ON Semiconductor Corp Common Stock 682189105   495 6,016 SH   SOLE   6,016 0 0
Cintas Corp Common Stock 172908105   494 1,067 SH   SOLE   1,067 0 0
Kraft Heinz Co/The Common Stock 500754106   479 12,394 SH   SOLE   12,394 0 0
Airbnb Inc Common Stock 009066101   453 3,642 SH   SOLE   3,642 0 0
Fate Therapeutics Inc Common Stock 31189P102   451 79,137 SH   SOLE   79,137 0 0
Coca-Cola Co/The Common Stock 191216100   450 7,250 SH   SOLE   7,250 0 0
Arista Networks Inc Common Stock 040413106   449 2,672 SH   SOLE   2,672 0 0
Exelixis Inc Common Stock 30161Q104   449 23,153 SH   SOLE   23,153 0 0
Exelon Corp Common Stock 30161N101   448 10,705 SH   SOLE   10,705 0 0
TE Connectivity Ltd Common Stock H84989104   448 3,416 SH   SOLE   3,416 0 0
Catalyst Pharmaceuticals Inc Common Stock 14888U101   437 26,379 SH   SOLE   26,379 0 0
IVERIC bio Inc Common Stock 46583P102   436 17,913 SH   SOLE   17,913 0 0
Paychex Inc Common Stock 704326107   436 3,809 SH   SOLE   3,809 0 0
Abbott Laboratories Common Stock 002824100   429 4,240 SH   SOLE   4,240 0 0
Las Vegas Sands Corp Common Stock 517834107   428 7,458 SH   SOLE   7,458 0 0
Arcus Biosciences Inc Common Stock 03969F109   426 23,335 SH   SOLE   23,335 0 0
Alnylam Pharmaceuticals Inc Common Stock 02043Q107   424 2,115 SH   SOLE   2,115 0 0
PTC Therapeutics Inc Common Stock 69366J200   423 8,732 SH   SOLE   8,732 0 0
Exact Sciences Corp Common Stock 30063P105   422 6,230 SH   SOLE   6,230 0 0
Ardelyx Inc Common Stock 039697107   421 87,893 SH   SOLE   87,893 0 0
Travere Therapeutics Inc Common Stock 89422G107   417 18,532 SH   SOLE   18,532 0 0
BioMarin Pharmaceutical Inc Common Stock 09061G101   415 4,268 SH   SOLE   4,268 0 0
Relay Therapeutics Inc Common Stock 75943R102   415 25,192 SH   SOLE   25,192 0 0
Blueprint Medicines Corp Common Stock 09627Y109   414 9,195 SH   SOLE   9,195 0 0
TG Therapeutics Inc Common Stock 88322Q108   413 27,428 SH   SOLE   27,428 0 0
PACCAR Inc Common Stock 693718108   412 5,627 SH   SOLE   5,627 0 0
Novavax Inc Common Stock 670002401   410 59,231 SH   SOLE   59,231 0 0
Alkermes PLC Common Stock G01767105   409 14,513 SH   SOLE   14,513 0 0
Apellis Pharmaceuticals Inc Common Stock 03753U106   409 6,207 SH   SOLE   6,207 0 0
Danaher Corp Common Stock 235851102   409 1,622 SH   SOLE   1,622 0 0
Neurocrine Biosciences Inc Common Stock 64125C109   408 4,031 SH   SOLE   4,031 0 0
Ionis Pharmaceuticals Inc Common Stock 462222100   406 11,372 SH   SOLE   11,372 0 0
CRISPR Therapeutics AG Common Stock H17182108   404 8,936 SH   SOLE   8,936 0 0
REVOLUTION Medicines Inc Common Stock 76155X100   403 18,603 SH   SOLE   18,603 0 0
Intellia Therapeutics Inc Common Stock 45826J105   402 10,782 SH   SOLE   10,782 0 0
Ultragenyx Pharmaceutical Inc Common Stock 90400D108   400 9,964 SH   SOLE   9,964 0 0
Xcel Energy Inc Common Stock 98389B100   399 5,917 SH   SOLE   5,917 0 0
Vir Biotechnology Inc Common Stock 92764N102   397 17,081 SH   SOLE   17,081 0 0
Natera Inc Common Stock 632307104   396 7,135 SH   SOLE   7,135 0 0
Sage Therapeutics Inc Common Stock 78667J108   395 9,412 SH   SOLE   9,412 0 0
Ross Stores Inc Common Stock 778296103   394 3,709 SH   SOLE   3,709 0 0
Karuna Therapeutics Inc Common Stock 48576A100   392 2,157 SH   SOLE   2,157 0 0
Old Dominion Freight Line Inc Common Stock 679580100   392 1,149 SH   SOLE   1,149 0 0
Prothena Corp PLC Common Stock G72800108   390 8,049 SH   SOLE   8,049 0 0
BioCryst Pharmaceuticals Inc Common Stock 09058V103   389 46,585 SH   SOLE   46,585 0 0
Warner Bros Discovery Inc Common Stock 934423104   389 25,759 SH   SOLE   25,759 0 0
Madrigal Pharmaceuticals Inc Common Stock 558868105   387 1,599 SH   SOLE   1,599 0 0
Walmart Inc Common Stock 931142103   385 2,613 SH   SOLE   2,613 0 0
Horizon Therapeutics Plc Common Stock G46188101   383 3,510 SH   SOLE   3,510 0 0
Vaxcyte Inc Common Stock 92243G108   383 10,212 SH   SOLE   10,212 0 0
Cytokinetics Inc Common Stock 23282W605   382 10,848 SH   SOLE   10,848 0 0
McDonald's Corp Common Stock 580135101   382 1,365 SH   SOLE   1,365 0 0
Iovance Biotherapeutics Inc Common Stock 462260100   380 62,188 SH   SOLE   62,188 0 0
Copart Inc Common Stock 217204106   379 5,044 SH   SOLE   5,044 0 0
United Therapeutics Corp Common Stock 91307C102   378 1,689 SH   SOLE   1,689 0 0
Align Technology Inc Common Stock 016255101   377 1,128 SH   SOLE   1,128 0 0
Bristol-Myers Squibb Co Common Stock 110122108   376 5,424 SH   SOLE   5,424 0 0
Workday Inc Common Stock 98138H101   375 1,817 SH   SOLE   1,817 0 0
Amicus Therapeutics Inc Common Stock 03152W109   374 33,758 SH   SOLE   33,758 0 0
Arrowhead Pharmaceuticals Inc Common Stock 04280A100   373 14,679 SH   SOLE   14,679 0 0
AstraZeneca PLC ADR 046353108   373 5,370 SH   SOLE   5,370 0 0
Bank of America Corp Common Stock 060505104   372 13,001 SH   SOLE   13,001 0 0
Ironwood Pharmaceuticals Inc Common Stock 46333X108   372 35,319 SH   SOLE   35,319 0 0
Sarepta Therapeutics Inc Common Stock 803607100   370 2,684 SH   SOLE   2,684 0 0
Twist Bioscience Corp Common Stock 90184D100   369 24,474 SH   SOLE   24,474 0 0
Beam Therapeutics Inc Common Stock 07373V105   368 12,016 SH   SOLE   12,016 0 0
Veracyte Inc Common Stock 92337F107   368 16,507 SH   SOLE   16,507 0 0
Insmed Inc Common Stock 457669307   366 21,479 SH   SOLE   21,479 0 0
Mirati Therapeutics Inc Common Stock 60468T105   366 9,847 SH   SOLE   9,847 0 0
Prometheus Biosciences Inc Common Stock 74349U108   362 3,377 SH   SOLE   3,377 0 0
Akero Therapeutics Inc Common Stock 00973Y108   357 9,340 SH   SOLE   9,340 0 0
ACADIA Pharmaceuticals Inc Common Stock 004225108   355 18,867 SH   SOLE   18,867 0 0
Halozyme Therapeutics Inc Common Stock 40637H109   354 9,277 SH   SOLE   9,277 0 0
Electronic Arts Inc Common Stock 285512109   353 2,929 SH   SOLE   2,929 0 0
Kymera Therapeutics Inc Common Stock 501575104   352 11,870 SH   SOLE   11,870 0 0
GLOBALFOUNDRIES Inc Common Stock G39387108   350 4,855 SH   SOLE   4,855 0 0
Walt Disney Co/The Common Stock 254687106   341 3,403 SH   SOLE   3,403 0 0
Syndax Pharmaceuticals Inc Common Stock 87164F105   339 16,065 SH   SOLE   16,065 0 0
Dollar Tree Inc Common Stock 256746108   338 2,358 SH   SOLE   2,358 0 0
Denali Therapeutics Inc Common Stock 24823R105   337 14,619 SH   SOLE   14,619 0 0
Fastenal Co Common Stock 311900104   332 6,149 SH   SOLE   6,149 0 0
Linde PLC Common Stock G54950103   326 918 SH   SOLE   918 0 0
MannKind Corp Common Stock 56400P706   322 78,504 SH   SOLE   78,504 0 0
SpringWorks Therapeutics Inc Common Stock 85205L107   320 12,422 SH   SOLE   12,422 0 0
Verisk Analytics Inc Common Stock 92345Y106   320 1,670 SH   SOLE   1,670 0 0
Baker Hughes Co Common Stock 05722G100   314 10,880 SH   SOLE   10,880 0 0
Roivant Sciences Ltd Common Stock G76279101   313 42,346 SH   SOLE   42,346 0 0
Walgreens Boots Alliance Inc Common Stock 931427108   312 9,016 SH   SOLE   9,016 0 0
Keysight Technologies Inc Common Stock 49338L103   311 1,926 SH   SOLE   1,926 0 0
Verizon Communications Inc Common Stock 92343V104   304 7,823 SH   SOLE   7,823 0 0
Elevance Health Inc Common Stock 036752103   303 658 SH   SOLE   658 0 0
CoStar Group Inc Common Stock 22160N109   302 4,381 SH   SOLE   4,381 0 0
Dynavax Technologies Corp Common Stock 268158201   301 30,717 SH   SOLE   30,717 0 0
Medtronic PLC Common Stock G5960L103   301 3,735 SH   SOLE   3,735 0 0
Celldex Therapeutics Inc Common Stock 15117B202   298 8,271 SH   SOLE   8,271 0 0
ImmunoGen Inc Common Stock 45253H101   298 77,663 SH   SOLE   77,663 0 0
Rambus Inc Common Stock 750917106   296 5,775 SH   SOLE   5,775 0 0
Bluebird Bio Inc Common Stock 09609G100   293 92,143 SH   SOLE   92,143 0 0
Cerevel Therapeutics Holdings Common Stock 15678U128   291 11,932 SH   SOLE   11,932 0 0
Rocket Pharmaceuticals Inc Common Stock 77313F106   291 17,001 SH   SOLE   17,001 0 0
Corning Inc Common Stock 219350105   290 8,215 SH   SOLE   8,215 0 0
Immunovant Inc Common Stock 45258J102   289 18,623 SH   SOLE   18,623 0 0
CDW Corp/DE Common Stock 12514G108   285 1,462 SH   SOLE   1,462 0 0
NextEra Energy Inc Common Stock 65339F101   285 3,702 SH   SOLE   3,702 0 0
Stryker Corp Common Stock 863667101   284 994 SH   SOLE   994 0 0
Editas Medicine Inc Common Stock 28106W103   282 38,855 SH   SOLE   38,855 0 0
Philip Morris International In Common Stock 718172109   281 2,888 SH   SOLE   2,888 0 0
Krystal Biotech Inc Common Stock 501147102   279 3,488 SH   SOLE   3,488 0 0
Credo Technology Group Holding Common Stock G25457105   278 29,479 SH   SOLE   29,479 0 0
Gartner Inc Common Stock 366651107   278 854 SH   SOLE   854 0 0
Constellation Energy Corp Common Stock 21037T109   277 3,524 SH   SOLE   3,524 0 0
Royal Caribbean Cruises Ltd Common Stock V7780T103   277 4,244 SH   SOLE   4,244 0 0
Biohaven Ltd Common Stock G1110E107   276 20,233 SH   SOLE   20,233 0 0
89bio Inc Common Stock 282559103   276 18,140 SH   SOLE   18,140 0 0
HP Inc Common Stock 40434L105   274 9,327 SH   SOLE   9,327 0 0
CTI BioPharma Corp Common Stock 12648L601   271 64,520 SH   SOLE   64,520 0 0
CVS Health Corp Common Stock 126650100   270 3,639 SH   SOLE   3,639 0 0
Agios Pharmaceuticals Inc Common Stock 00847X104   269 11,701 SH   SOLE   11,701 0 0
Avidity Biosciences Inc Common Stock 05370A108   269 17,521 SH   SOLE   17,521 0 0
Diamondback Energy Inc Common Stock 25278X109   268 1,979 SH   SOLE   1,979 0 0
Crowdstrike Holdings Inc Common Stock 22788C105   267 1,945 SH   SOLE   1,945 0 0
Raytheon Technologies Corp Common Stock 75513E101   267 2,729 SH   SOLE   2,729 0 0
Wells Fargo & Co Common Stock 949746101   265 7,098 SH   SOLE   7,098 0 0
United Parcel Service Inc Common Stock 911312106   264 1,360 SH   SOLE   1,360 0 0
FibroGen Inc Common Stock 31572Q808   260 13,951 SH   SOLE   13,951 0 0
Rhythm Pharmaceuticals Inc Common Stock 76243J105   258 14,484 SH   SOLE   14,484 0 0
Scilex Holding Co Common Stock 80880W106   258 31,431 SH   SOLE   31,431 0 0
eBay Inc Common Stock 278642103   257 5,793 SH   SOLE   5,793 0 0
AT&T Inc Common Stock 00206R102   256 13,277 SH   SOLE   13,277 0 0
Viridian Therapeutics Inc Common Stock 92790C104   256 10,044 SH   SOLE   10,044 0 0
Bridgebio Pharma Inc Common Stock 10806X102   252 15,216 SH   SOLE   15,216 0 0
Arcellx Inc Common Stock 03940C100   247 8,032 SH   SOLE   8,032 0 0
uniQure NV Common Stock N90064101   247 12,246 SH   SOLE   12,246 0 0
Zoetis Inc Common Stock 98978V103   244 1,466 SH   SOLE   1,466 0 0
Monolithic Power Systems Inc Common Stock 609839105   242 484 SH   SOLE   484 0 0
Chinook Therapeutics Inc Common Stock 16961L106   238 10,289 SH   SOLE   10,289 0 0
Boston Scientific Corp Common Stock 101137107   237 4,743 SH   SOLE   4,743 0 0
Becton Dickinson & Co Common Stock 075887109   235 950 SH   SOLE   950 0 0
First Solar Inc Common Stock 336433107   233 1,071 SH   SOLE   1,071 0 0
Cigna Group/The Common Stock 125523100   232 906 SH   SOLE   906 0 0
Atlassian Corp Common Stock 049468101   229 1,337 SH   SOLE   1,337 0 0
Union Pacific Corp Common Stock 907818108   229 1,140 SH   SOLE   1,140 0 0
Geron Corp Common Stock 374163103   227 104,721 SH   SOLE   104,721 0 0
Teledyne Technologies Inc Common Stock 879360105   227 507 SH   SOLE   507 0 0
Anavex Life Sciences Corp Common Stock 032797300   226 26,414 SH   SOLE   26,414 0 0
ConocoPhillips Common Stock 20825C104   226 2,280 SH   SOLE   2,280 0 0
Emergent BioSolutions Inc Common Stock 29089Q105   225 21,746 SH   SOLE   21,746 0 0
Lowe's Cos Inc Common Stock 548661107   225 1,127 SH   SOLE   1,127 0 0
Myriad Genetics Inc Common Stock 62855J104   224 9,639 SH   SOLE   9,639 0 0
Boeing Co/The Common Stock 097023105   223 1,048 SH   SOLE   1,048 0 0
Caterpillar Inc Common Stock 149123101   222 970 SH   SOLE   970 0 0
Hewlett Packard Enterprise Co Common Stock 42824C109   220 13,833 SH   SOLE   13,833 0 0
Arcturus Therapeutics Holdings Common Stock 03969T109   217 9,073 SH   SOLE   9,073 0 0
Replimune Group Inc Common Stock 76029N106   217 12,305 SH   SOLE   12,305 0 0
Prologis Inc REIT 74340W103   215 1,720 SH   SOLE   1,720 0 0
Verve Therapeutics Inc Common Stock 92539P101   215 14,936 SH   SOLE   14,936 0 0
Morgan Stanley Common Stock 617446448   214 2,434 SH   SOLE   2,434 0 0
S&P Global Inc Common Stock 78409V104   212 614 SH   SOLE   614 0 0
CareDx Inc Common Stock 14167L103   211 23,122 SH   SOLE   23,122 0 0
Humana Inc Common Stock 444859102   211 435 SH   SOLE   435 0 0
VeriSign Inc Common Stock 92343E102   209 989 SH   SOLE   989 0 0
Deere & Co Common Stock 244199105   208 504 SH   SOLE   504 0 0
HCA Healthcare Inc Common Stock 40412C101   207 786 SH   SOLE   786 0 0
Goldman Sachs Group Inc/The Common Stock 38141G104   206 631 SH   SOLE   631 0 0
Deciphera Pharmaceuticals Inc Common Stock 24344T101   205 13,288 SH   SOLE   13,288 0 0
Edwards Lifesciences Corp Common Stock 28176E108   203 2,449 SH   SOLE   2,449 0 0
Skyworks Solutions Inc Common Stock 83088M102   203 1,717 SH   SOLE   1,717 0 0
Zentalis Pharmaceuticals Inc Common Stock 98943L107   203 11,821 SH   SOLE   11,821 0 0
Karyopharm Therapeutics Inc Common Stock 48576U106   202 51,849 SH   SOLE   51,849 0 0
Xencor Inc Common Stock 98401F105   201 7,213 SH   SOLE   7,213 0 0
Lockheed Martin Corp Common Stock 539830109   200 424 SH   SOLE   424 0 0
Protagonist Therapeutics Inc Common Stock 74366E102   200 8,713 SH   SOLE   8,713 0 0
Intercept Pharmaceuticals Inc Common Stock 45845P108   199 14,790 SH   SOLE   14,790 0 0
Kura Oncology Inc Common Stock 50127T109   191 15,588 SH   SOLE   15,588 0 0
Allogene Therapeutics Inc Common Stock 019770106   190 38,437 SH   SOLE   38,437 0 0
Arcutis Biotherapeutics Inc Common Stock 03969K108   190 17,299 SH   SOLE   17,299 0 0
Agenus Inc Common Stock 00847G705   188 123,851 SH   SOLE   123,851 0 0
Avid Bioservices Inc Common Stock 05368M106   188 10,037 SH   SOLE   10,037 0 0
ADMA Biologics Inc Common Stock 000899104   184 55,703 SH   SOLE   55,703 0 0
Coherus Biosciences Inc Common Stock 19249H103   156 22,741 SH   SOLE   22,741 0 0
Cogent Biosciences Inc Common Stock 19240Q201   148 13,749 SH   SOLE   13,749 0 0
Day One Biopharmaceuticals Inc Common Stock 23954D109   145 10,867 SH   SOLE   10,867 0 0
Recursion Pharmaceuticals Inc Common Stock 75629V104   143 21,417 SH   SOLE   21,417 0 0
Sirius XM Holdings Inc Common Stock 82968B103   138 34,649 SH   SOLE   34,649 0 0
Lucid Group Inc Common Stock 549498103   131 16,303 SH   SOLE   16,303 0 0
2seventy bio Inc Common Stock 901384107   129 12,601 SH   SOLE   12,601 0 0
Altimmune Inc Common Stock 02155H200   124 29,334 SH   SOLE   29,334 0 0
EQRx Inc Common Stock 26886C107   121 62,580 SH   SOLE   62,580 0 0
Viatris Inc Common Stock 92556V106   114 11,886 SH   SOLE   11,886 0 0
Mersana Therapeutics Inc Common Stock 59045L106   113 27,578 SH   SOLE   27,578 0 0
Inovio Pharmaceuticals Inc Common Stock 45773H201   106 129,289 SH   SOLE   129,289 0 0
Allakos Inc Common Stock 01671P100   95 21,450 SH   SOLE   21,450 0 0
Atara Biotherapeutics Inc Common Stock 046513107   93 32,062 SH   SOLE   32,062 0 0
Vanda Pharmaceuticals Inc Common Stock 921659108   89 13,060 SH   SOLE   13,060 0 0
Alector Inc Common Stock 014442107   87 14,089 SH   SOLE   14,089 0 0
Seres Therapeutics Inc Common Stock 81750R102   77 13,585 SH   SOLE   13,585 0 0
Sana Biotechnology Inc Common Stock 799566104   76 23,180 SH   SOLE   23,180 0 0
Caribou Biosciences Inc Common Stock 142038108   70 13,274 SH   SOLE   13,274 0 0
Lyell Immunopharma Inc Common Stock 55083R104   68 28,738 SH   SOLE   28,738 0 0
Sangamo Therapeutics Inc Common Stock 800677106   62 35,003 SH   SOLE   35,003 0 0
Sutro Biopharma Inc Common Stock 869367102   57 12,245 SH   SOLE   12,245 0 0
Kezar Life Sciences Inc Common Stock 49372L100   44 14,149 SH   SOLE   14,149 0 0