The Securities and Exchange Commission has not necessarily reviewed the information in this filing and has not determined if it is accurate and complete.
The reader should not assume that the information is accurate and complete.

UNITED STATES SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549
FORM 13F

FORM 13F INFORMATION TABLE
OMB APPROVAL
OMB Number: 3235-0006
Estimated average burden
hours per response: 23.8
COLUMN 1 COLUMN 2 COLUMN 3 COLUMN 4 COLUMN 5 COLUMN 6 COLUMN 7 COLUMN 8
VALUE SHRS OR SH/ PUT/ INVESTMENT OTHER VOTING AUTHORITY
NAME OF ISSUER TITLE OF CLASS CUSIP FIGI (to the nearest dollar) PRN AMT PRN CALL DISCRETION MANAGER SOLE SHARED NONE
4D MOLECULAR THERAPEUTICS IN COM 35104E100   96,677,673 3,034,453 SH   SOLE   3,034,453 0 0
ABIVAX SA SPONSORED ADS 00370M103   61,453,363 4,297,438 SH   SOLE   4,297,438 0 0
AGENUS INC COM NEW 00847G705   18,384,573 31,697,539 SH   SOLE   31,697,539 0 0
ALECTOR INC COM 014442107   22,691,704 3,769,386 SH   SOLE   3,769,386 0 0
ALIGOS THERAPEUTICS INC COM 01626L105   5,980,715 6,102,770 SH   SOLE   6,102,770 0 0
ALKERMES PLC SHS G01767105   94,745,000 3,500,000 SH   SOLE   3,500,000 0 0
ALLAKOS INC COM 01671P100   6,300,000 5,000,000 SH   SOLE   5,000,000 0 0
ALNYLAM PHARMACEUTICALS INC COM 02043Q107   124,388,730 832,310 SH   SOLE   832,310 0 0
ALTO NEUROSCIENCE INC COM SHS 02157Q109   9,210,000 600,000 SH   SOLE   600,000 0 0
AMGEN INC COM 031162100   156,376,000 550,000 SH   SOLE   550,000 0 0
ANAPTYSBIO INC COM 032724106   11,923,259 529,452 SH   SOLE   529,452 0 0
ANI PHARMACEUTICALS INC COM 00182C103   56,824,929 822,001 SH   SOLE   822,001 0 0
APELLIS PHARMACEUTICALS INC COM 03753U106   58,780,000 1,000,000 SH   SOLE   1,000,000 0 0
APOGEE THERAPEUTICS INC COM 03770N101   154,393,651 2,323,456 SH   SOLE   2,323,456 0 0
ARGENX SE SPONSORED ADR 04016X101   118,116,000 300,000 SH   SOLE   300,000 0 0
AUTOLUS THERAPEUTICS PLC SPON ADS 05280R100   97,436,457 15,272,172 SH   SOLE   15,272,172 0 0
AXSOME THERAPEUTICS INC COM 05464T104   104,116,736 1,304,721 SH   SOLE   1,304,721 0 0
BICYCLE THERAPEUTICS PLC SPONSORED ADS 088786108   86,913,599 3,490,506 SH   SOLE   3,490,506 0 0
COGENT BIOSCIENCES INC COM 19240Q201   2,123,520 316,000 SH   SOLE   316,000 0 0
CYBIN INC COM 23256X100   24,040,698 58,139,535 SH   SOLE   58,139,535 0 0
DYNAVAX TECHNOLOGIES CORP COM NEW 268158201   113,448,001 9,141,660 SH   SOLE   9,141,660 0 0
DYNE THERAPEUTICS INC COM 26818M108   129,327,323 4,555,383 SH   SOLE   4,555,383 0 0
EDITAS MEDICINE INC COM 28106W103   41,012,492 5,527,290 SH   SOLE   5,527,290 0 0
ENGENE HOLDINGS INC COM 29286M105   38,137,500 2,250,000 SH   SOLE   2,250,000 0 0
FATE THERAPEUTICS INC COM 31189P102   40,902,935 5,572,607 SH   SOLE   5,572,607 0 0
GERON CORP COM 374163103   100,669,566 30,505,929 SH   SOLE   30,505,929 0 0
GUARDANT HEALTH INC COM 40131M109   123,780,000 6,000,000 SH   SOLE   6,000,000 0 0
HILLEVAX INC COM 43157M102   42,780,010 2,572,460 SH   SOLE   2,572,460 0 0
IMMUNOVANT INC COM 45258J102   15,940,203 493,352 SH   SOLE   493,352 0 0
INSMED INC COM PAR $.01 457669307   129,781,211 4,783,679 SH   SOLE   4,783,679 0 0
INTELLIA THERAPEUTICS INC COM 45826J105   115,838,668 4,210,784 SH   SOLE   4,210,784 0 0
INTRA-CELLULAR THERAPIES INC COM 46116X101   12,137,680 175,400 SH Put SOLE   175,400 0 0
INTRA-CELLULAR THERAPIES INC COM 46116X101   103,800,000 1,500,000 SH   SOLE   1,500,000 0 0
INVIVYD INC COM 00534A102   48,635,480 10,953,937 SH   SOLE   10,953,937 0 0
IONIS PHARMACEUTICALS INC COM 462222100   59,540,141 1,373,475 SH   SOLE   1,373,475 0 0
KYMERA THERAPEUTICS INC COM 501575104   50,742,289 1,262,246 SH   SOLE   1,262,246 0 0
MERSANA THERAPEUTICS INC COM 59045L106   2,596,940 579,674 SH   SOLE   579,674 0 0
METAGENOMI INC COM 59102M104   4,918,748 466,232 SH   SOLE   466,232 0 0
MIND MEDICINE MINDMED INC COM NEW 60255C885   62,666,670 6,666,667 SH   SOLE   6,666,667 0 0
NEKTAR THERAPEUTICS COM 640268108   17,189,280 18,400,000 SH   SOLE   18,400,000 0 0
NEUMORA THERAPEUTICS INC. COM 640979100   13,750,000 1,000,000 SH   SOLE   1,000,000 0 0
NURIX THERAPEUTICS INC COM 67080M103   44,068,101 2,997,830 SH   SOLE   2,997,830 0 0
NUVALENT INC COM 670703107   20,613,106 274,512 SH   SOLE   274,512 0 0
OCULAR THERAPEUTIX INC COM 67576A100   115,765,286 12,721,460 SH   SOLE   12,721,460 0 0
OLEMA PHARMACEUTICALS INC COM 68062P106   36,511,743 3,225,419 SH   SOLE   3,225,419 0 0
PACIFIC BIOSCIENCES CALIF IN COM 69404D108   26,250,000 7,000,000 SH   SOLE   7,000,000 0 0
PLIANT THERAPEUTICS INC COM 729139105   85,675,000 5,750,000 SH   SOLE   5,750,000 0 0
PRIME MEDICINE INC COM 74168J101   2,126,012 303,716 SH   SOLE   303,716 0 0
PYXIS ONCOLOGY INC COMMON STOCK 747324101   17,824,266 4,184,100 SH   SOLE   4,184,100 0 0
REGULUS THERAPEUTICS INC COM 75915K309   9,407,710 3,266,566 SH   SOLE   3,266,566 0 0
RELMADA THERAPEUTICS INC COM 75955J402   5,766,158 1,240,034 SH   SOLE   1,240,034 0 0
REPARE THERAPEUTICS INC COM 760273102   12,643,260 2,684,344 SH   SOLE   2,684,344 0 0
SCHOLAR ROCK HLDG CORP COM 80706P103   12,076,800 680,000 SH   SOLE   680,000 0 0
SILENCE THERAPEUTICS PLC ADS 82686Q101   35,507,830 1,643,881 SH   SOLE   1,643,881 0 0
SPRINGWORKS THERAPEUTICS INC COM 85205L107   171,278,365 3,479,853 SH   SOLE   3,479,853 0 0
SPYRE THERAPEUTICS INC COM NEW 00773J202   46,025,021 1,213,420 SH   SOLE   1,213,420 0 0
STRUCTURE THERAPEUTICS INC SPONSORED ADS 86366E106   1,720,272 40,137 SH   SOLE   40,137 0 0
SYROS PHARMACEUTICALS INC COM NEW 87184Q206   4,432,395 828,485 SH   SOLE   828,485 0 0
TERNS PHARMACEUTICALS INC COM 880881107   40,016,000 6,100,000 SH   SOLE   6,100,000 0 0
TRAVERE THERAPEUTICS INC COM 89422G107   56,822,700 7,370,000 SH   SOLE   7,370,000 0 0
TOURMALINE BIO INC COM 89157D105   36,534,660 1,595,400 SH   SOLE   1,595,400 0 0
ULTRAGENYX PHARMACEUTICAL IN COM 90400D108   7,833,835 167,784 SH   SOLE   167,784 0 0
VERONA PHARMA PLC SPONSORED ADS 925050106   51,285,507 3,187,415 SH   SOLE   3,187,415 0 0
VIGIL NEUROSCIENCE INC COM 92673K108   5,438,715 1,594,931 SH   SOLE   1,594,931 0 0
VIRIDIAN THERAPEUTICS INC COM 92790C104   60,515,488 3,456,053 SH   SOLE   3,456,053 0 0
ZURA BIO LTD CLASS A ORD SHS G9TY5A101   6,484,110 2,523,000 SH   SOLE   2,523,000 0 0