The Securities and Exchange Commission has not necessarily reviewed the information in this filing and has not determined if it is accurate and complete.
The reader should not assume that the information is accurate and complete.

UNITED STATES SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549
FORM 13F

FORM 13F INFORMATION TABLE
OMB APPROVAL
OMB Number: 3235-0006
Estimated average burden
hours per response: 23.8
COLUMN 1 COLUMN 2 COLUMN 3 COLUMN 4 COLUMN 5 COLUMN 6 COLUMN 7 COLUMN 8
VALUE SHRS OR SH/ PUT/ INVESTMENT OTHER VOTING AUTHORITY
NAME OF ISSUER TITLE OF CLASS CUSIP FIGI (to the nearest dollar) PRN AMT PRN CALL DISCRETION MANAGER SOLE SHARED NONE
10X GENOMICS INC CL A COM 88025U109   9,780,549 502,856 SH   SOLE   502,856 0 0
89BIO INC COM 282559103   59,102,169 7,378,548 SH   SOLE   7,378,548 0 0
ACADIA PHARMACEUTICALS INC COM 004225108   222,746,973 13,707,506 SH   SOLE   13,707,506 0 0
ACELYRIN INC COM 00445A100   4,314,347 978,310 SH   SOLE   978,310 0 0
ADICET BIO INC COM 007002108   1,274,962 1,053,688 SH   SOLE   1,053,688 0 0
AKERO THERAPEUTICS INC COM 00973Y108   127,434,368 5,431,985 SH   SOLE   5,431,985 0 0
ALKERMES PLC SHS G01767105   170,073,411 7,056,988 SH   SOLE   7,056,988 0 0
ALLURION TECHNOLOGIES INC COM SHS 02008G102   3,688,675 3,697,549 SH   SOLE   3,697,549 0 0
APOGEE THERAPEUTICS INC COM 03770N101   106,720,978 2,712,096 SH   SOLE   2,712,096 0 0
ARCA BIOPHARMA INC COM 00211Y506   5,362,000 1,400,000 SH   SOLE   1,400,000 0 0
ARGENX SE SPONSORED ADR 04016X101   281,431,077 654,430 SH   SOLE   654,430 0 0
ARVINAS INC COM 04335A105   79,005,418 2,967,897 SH   SOLE   2,967,897 0 0
ARYA SCIENCES ACQU CORP IV CL A G31659108   1,467,816 127,970 SH   SOLE   127,970 0 0
AVIDITY BIOSCIENCES INC COM 05370A108   359,759,332 8,806,838 SH   SOLE   8,806,838 0 0
AXSOME THERAPEUTICS INC COM 05464T104   373,063,646 4,634,331 SH   SOLE   4,634,331 0 0
BRUKER CORP COM 116794108   219,767,702 3,444,095 SH   SOLE   3,444,095 0 0
CARGO THERAPEUTICS INC COM 14179K101   66,962,763 4,078,122 SH   SOLE   4,078,122 0 0
CG ONCOLOGY INC COM 156944100   42,432,416 1,344,074 SH   SOLE   1,344,074 0 0
CULLINAN THERAPEUTICS INC COM 230031106   18,357,867 1,052,630 SH   SOLE   1,052,630 0 0
CUTERA INC COM 232109108   2,010,982 1,331,776 SH   SOLE   1,331,776 0 0
CYTOKINETICS INC COM NEW 23282W605   147,432,340 2,721,158 SH   SOLE   2,721,158 0 0
CYTOMX THERAPEUTICS INC COM 23284F105   1,464,002 1,200,002 SH   SOLE   1,200,002 0 0
DIANTHUS THERAPEUTICS INC COM 252828108   17,253,342 666,667 SH   SOLE   666,667 0 0
DYNE THERAPEUTICS INC COM 26818M108   225,402,100 6,387,138 SH   SOLE   6,387,138 0 0
ESSA PHARMA INC COM NEW 29668H708   12,090,962 2,298,662 SH   SOLE   2,298,662 0 0
ESTABLISHMENT LABS HLDGS INC COM G31249108   121,583,944 2,675,703 SH   SOLE   2,675,703 0 0
EXAGEN INC COM 30068X103   2,751,596 1,511,866 SH   SOLE   1,511,866 0 0
FULCRUM THERAPEUTICS INC COM 359616109   36,244,927 5,845,956 SH   SOLE   5,845,956 0 0
GH RESEARCH PLC ORDINARY SHARES G3855L106   38,794,324 3,327,129 SH   SOLE   3,327,129 0 0
GLAUKOS CORP COM 377322102   45,717,540 386,291 SH   SOLE   386,291 0 0
IMMATICS N.V SHS N44445109   116,200,000 10,000,000 SH   SOLE   10,000,000 0 0
IMMUNIC INC COM 4525EP101   5,070,166 4,567,717 SH   SOLE   4,567,717 0 0
IMMUNOCORE HLDGS PLC ADS 45258D105   165,037,454 4,869,798 SH   SOLE   4,869,798 0 0
INSMED INC COM PAR $.01 457669307   243,887,236 3,640,108 SH   SOLE   3,640,108 0 0
INTUITIVE SURGICAL INC COM NEW 46120E602   90,062,552 202,456 SH   SOLE   202,456 0 0
KYVERNA THERAPEUTICS INC COM 501976104   13,895,333 1,852,711 SH   SOLE   1,852,711 0 0
LENZ THERAPEUTICS INC COM 52635N103   14,927,996 863,389 SH   SOLE   863,389 0 0
MADRIGAL PHARMACEUTICALS INC COM 558868105   536,747,898 1,915,862 SH   SOLE   1,915,862 0 0
MASIMO CORP COM 574795100   184,174,656 1,462,400 SH   SOLE   1,462,400 0 0
MERUS N V COM N5749R100   246,702,984 4,169,393 SH   SOLE   4,169,393 0 0
MILESTONE PHARMACEUTICALS IN COM 59935V107   4,298,055 3,256,102 SH   SOLE   3,256,102 0 0
NATERA INC COM 632307104   280,830,948 2,593,323 SH   SOLE   2,593,323 0 0
NEUROGENE INC COM 64135M105   38,957,860 1,070,565 SH   SOLE   1,070,565 0 0
ORCHESTRA BIOMED HLDGS INC COM 68572M106   45,808,216 5,620,640 SH   SOLE   5,620,640 0 0
PENUMBRA INC COM 70975L107   133,556,637 742,105 SH   SOLE   742,105 0 0
PERCEPTIVE CAP SOLUTIONS COR CL A ORD SHS G70077105   7,469,550 742,500 SH   SOLE   742,500 0 0
PROTAGONIST THERAPEUTICS INC COM 74366E102   183,173,899 5,286,404 SH   SOLE   5,286,404 0 0
PTC THERAPEUTICS INC COM 69366J200   226,081,824 7,393,127 SH   SOLE   7,393,127 0 0
RADNET INC COM 750491102   109,356,109 1,856,010 SH   SOLE   1,856,010 0 0
REGENXBIO INC COM 75901B107   4,095,000 350,000 SH   SOLE   350,000 0 0
REPLIMUNE GROUP INC COM 76029N106   10,204,083 1,133,787 SH   SOLE   1,133,787 0 0
ROCKET PHARMACEUTICALS INC *W EXP 09/02/202 77313F114   21,245 350,000 SH   SOLE   350,000 0 0
ROCKET PHARMACEUTICALS INC COM 77313F106   380,817,731 17,687,772 SH   SOLE   17,687,772 0 0
ROIVANT SCIENCES LTD SHS G76279101   15,371,666 1,454,273 SH   SOLE   1,454,273 0 0
SAB BIOTHERAPEUTICS INC COM NEW 78397T202   2,377,533 766,946 SH   SOLE   766,946 0 0
SAGE THERAPEUTICS INC COM 78667J108   59,519,066 5,480,577 SH   SOLE   5,480,577 0 0
SAGIMET BIOSCIENCES INC COM SER A 786700104   1,710,000 500,000 SH   SOLE   500,000 0 0
SPYRE THERAPEUTICS INC COM NEW 00773J202   76,604,044 3,258,360 SH   SOLE   3,258,360 0 0
STOKE THERAPEUTICS INC COM 86150R107   57,077,561 4,224,838 SH   SOLE   4,224,838 0 0
STRUCTURE THERAPEUTICS INC SPONSORED ADS 86366E106   4,908,750 125,000 SH   SOLE   125,000 0 0
TARSUS PHARMACEUTICALS INC COM 87650L103   92,751,369 3,412,486 SH   SOLE   3,412,486 0 0
TAYSHA GENE THERAPIES INC COM SHS 877619106   42,112,670 18,800,299 SH   SOLE   18,800,299 0 0
TEMPUS AI INC CL A 88023B103   14,000,000 400,000 SH   SOLE   400,000 0 0
TOURMALINE BIO INC COM 89157D105   9,537,696 741,656 SH   SOLE   741,656 0 0
ULTRAGENYX PHARMACEUTICAL IN COM 90400D108   133,983,000 3,259,927 SH   SOLE   3,259,927 0 0
UROGEN PHARMA LTD COM M96088105   59,692,283 3,557,347 SH   SOLE   3,557,347 0 0
VERICEL CORP COM 92346J108   36,768,094 801,397 SH   SOLE   801,397 0 0
VIRIDIAN THERAPEUTICS INC COM 92790C104   7,881,666 605,816 SH   SOLE   605,816 0 0