Institutional shares held 32.1 Million
1.82M calls
1.09M puts
Total value of holdings $117M
$6.63M calls
$3.96M puts
Market Cap $284M
77,942,800 Shares Out.
Institutional ownership 41.12%
# of Institutions 211


Latest Institutional Activity in AVXL

Top Purchases

Q3 2025
State Street Corp Shares Held: 3.29M ($12M)
Q3 2025
Franklin Resources Inc Shares Held: 375K ($1.37M)
Q3 2025
Summit Financial, LLC Shares Held: 444K ($1.62M)
Q3 2025
Jane Street Group, LLC Shares Held: 218K ($794K)
Q3 2025
Sheets Smith Investment Management Shares Held: 136K ($495K)

Top Sells

Q3 2025
Invesco Ltd. Shares Held: 56.7K ($206K)
Q3 2025
Bank Of America Corp Shares Held: 171K ($622K)
Q3 2025
Nwam LLC Shares Held: 874K ($3.18M)
Q3 2025
Citadel Advisors LLC Shares Held: 196K ($712K)
Q3 2025
Morgan Stanley Shares Held: 560K ($2.04M)

About AVXL

Anavex Life Sciences Corp., a clinical stage biopharmaceutical company, engages in the development of drug candidates for the treatment of central nervous system (CNS) diseases. Its lead drug candidate is ANAVEX 2-73, which is in Phase III clinical trial for the treatment of Alzheimer's disease; Phase III clinical trial to treat pediatric patients with Rett syndrome; Phase II clinical trial for the treatment of Parkinson's disease; and preclinical clinical trials to treat epilepsy, infantile spasms, Fragile X syndrome, Angelman syndrome, multiple sclerosis, and tuberous sclerosis complex. The company's drug candidate also comprises ANAVEX 3-71, which is in Phase I clinical trial for the treatment of frontotemporal dementia and other dementia indications; and preclinical clinical trials for the treatment of neurodegenerative diseases, such as Alzheimer's and Parkinson's diseases. Its preclinical drug candidates include ANAVEX 1-41, a sigma-1 receptor agonist for the treatment of depression, stroke, Parkinson's, and Alzheimer's diseases; ANAVEX 1066, a mixed sigma-1/sigma-2 ligand for the potential treatment of neuropathic and visceral pain; and ANAVEX 1037 to treat prostate and pancreatic cancer. The company was incorporated in 2004 and is headquartered in New York, New York.


Insider Transactions at AVXL

Insider Transaction List

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Date Insider Transaction Ownership Type Shares Traded Value / Price
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Last 12 Months Summary

Buy / Acquisition
738K Shares
From 2 Insiders
Exercise of conversion of derivative security 738K shares
Sell / Disposition
439K Shares
From 2 Insiders
Payment of exercise price or tax liability 439K shares

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