Institutional shares held 200 Million
640K calls
507K puts
Total value of holdings $1.42B
$4.53M calls
$3.59M puts
Market Cap $1.32B
185,944,992 Shares Out.
Institutional ownership 107.51%
# of Institutions 310


Latest Institutional Activity in BCRX

Top Purchases

Q3 2025
Deerfield Management Company, L.P. (Series C) Shares Held: 12.2M ($86.2M)
Q3 2025
Hood River Capital Management LLC Shares Held: 3.62M ($25.6M)
Q3 2025
Jane Street Group, LLC Shares Held: 1.85M ($13.1M)
Q3 2025
State Street Corp Shares Held: 9.81M ($69.4M)
Q3 2025
Cubist Systematic Strategies, LLC Shares Held: 1.25M ($8.83M)

Top Sells

Q3 2025
Avoro Capital Advisors LLC Shares Held: 1.25M ($8.85M)
Q3 2025
D. E. Shaw & Co., Inc. Shares Held: 1.71M ($12.1M)
Q3 2025
Walleye Capital LLC Shares Held: 227K ($1.61M)
Q3 2025
Voloridge Investment Management, LLC Shares Held: 957K ($6.78M)
Q3 2025
Millennium Management LLC Shares Held: 461K ($3.26M)

About BCRX

BioCryst Pharmaceuticals, Inc., a biotechnology company, discovers novel, oral, and small-molecule medicines. The company markets peramivir injection, an intravenous neuraminidase inhibitor for the treatment of acute uncomplicated influenza under the RAPIVAB, RAPIACTA, and PERAMIFLU names; and ORLADEYO, an oral serine protease inhibitor to treat hereditary angioedema. It is also developing BCX9930, an oral factor D inhibitor, which is in Phase II clinical trial for complement-mediated diseases; BCX9250, an oral activin receptor-like kinase-2 inhibitor that is in Phase I clinical trial to treat fibrodysplasia ossificans progressiva; and Galidesivir, a RNA dependent-RNA polymerase inhibitor, which is in Phase I clinical trial to treat various RNA viruses, including Marburg, Yellow Fever, Ebola, and Zika. The company has collaborations and in-license relationships with the Torii Pharmaceutical Co., Ltd.; Seqirus UK Limited; Shionogi & Co., Ltd.; Green Cross Corporation; Mundipharma International Holdings Limited; National Institute of Allergy and Infectious Diseases; Biomedical Advanced Research and Development Authority; the U.S. Department of Health and Human Services; and The University of Alabama at Birmingham, as well as Albert Einstein College of Medicine of Yeshiva University and Industrial Research, Ltd. BioCryst Pharmaceuticals, Inc. was founded in 1986 and is headquartered in Durham, North Carolina.


Insider Transactions at BCRX

Insider Transaction List

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Date Insider Transaction Ownership Type Shares Traded Value / Price
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Last 12 Months Summary

Buy / Acquisition
1.29M Shares
From 17 Insiders
Grant, award, or other acquisition 1.11M shares
Bona fide gift 20K shares
Exercise of conversion of derivative security 161K shares
Sell / Disposition
356K Shares
From 9 Insiders
Open market or private sale 241K shares
Payment of exercise price or tax liability 94.4K shares
Bona fide gift 20K shares

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