Dirk Thye Cortexyme, Inc. (CRTX) insider trading activity

Dirk Thye is CEO and CMO of Cortexyme, Inc.. Currently has a direct ownership of 255,000 shares of CRTX, which is worth approximately $328,950. The most recent transaction as insider was on Dec 10, 2025, when has been sold 739,885 shares (Common Shares) at a price of $0.0 per share, resulting in proceeds of $0. This information was disclosed in a Form 4 filing with the Securities and Exchange Commission (SEC).

Shares Held (Direct Ownership) 255K

74.37% 3M change

69.78% 12M change

Total Value Held $328,950

Dirk Thye Transaction History

Date	Transaction	Value	Shares Traded	Shares Held
Dec 10 2025	SELL Bona fide gift	-	739,885 Reduced 74.37%	255,000 Common Shares
Jun 18 2025	BUY Grant, award, or other acquisition	$181,132 $1.2 p/Share	150,944 Added 13.17%	994,885 Common Shares
Aug 30 2024	BUY Open market or private purchase	$53,900 $0.7 p/Share	77,000 Added 8.36%	843,941 Common Stock
Aug 29 2024	BUY Open market or private purchase	$53,474 $0.69 p/Share	77,500 Added 9.18%	766,941 Common Stock
Jan 16 2024	BUY Exercise of conversion of derivative security	$180,397 $0.75 p/Share	240,530 Added 25.86%	689,441 Common Stock
Aug 10 2023	BUY Open market or private purchase	$110,880 $1.26 p/Share	88,000 Added 16.39%	448,911 Common Stock
Aug 08 2023	BUY Open market or private purchase	$99,200 $1.24 p/Share	80,000 Added 18.14%	360,911 Common Stock

May 19 2022	BUY Grant, award, or other acquisition	-	64,589 Added 50.0%	64,589 Common Stock

Dirk Thye

CEO and CMO

South San Francisco, CA

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