Institutional shares held 27.1 Million
42.2K calls
9.3K puts
Total value of holdings $906M
$1.41M calls
$311K puts
Market Cap $880M
26,297,000 Shares Out.
Institutional ownership 103.0%
# of Institutions 186


Latest Institutional Activity in CSTL

Top Purchases

Q3 2025
Aigh Capital Management LLC Shares Held: 707K ($23.7M)
Q3 2025
Summit Partners Public Asset Management, LLC Shares Held: 400K ($13.4M)
Q3 2025
Point72 Asset Management, L.P. Shares Held: 337K ($11.3M)
Q3 2025
Connor, Clark & Lunn Investment Management Ltd. Shares Held: 336K ($11.2M)
Q3 2025
Millennium Management LLC Shares Held: 575K ($19.2M)

Top Sells

Q3 2025
Citadel Advisors LLC Shares Held: 251K ($8.39M)
Q3 2025
Wasatch Advisors Inc Shares Held: 669K ($22.4M)
Q3 2025
Schroder Investment Management Group Shares Held: 495K ($16.6M)
Q3 2025
Trexquant Investment LP Shares Held: 178K ($5.97M)
Q3 2025
Algert Global LLC Shares Held: 57.9K ($1.94M)

About CSTL

Castle Biosciences, Inc., a commercial-stage diagnostics company, focuses to provide diagnostic and prognostic testing services for dermatological cancers. Its lead product is DecisionDx-Melanoma, a multi-gene expression profile (GEP) test to identify the risk of metastasis for patients diagnosed with invasive cutaneous melanoma. The company also offers DecisionDx-UM test, a proprietary GEP test that predicts the risk of metastasis for patients with uveal melanoma, a rare eye cancer; DecisionDx-SCC, a proprietary 40-gene expression profile test that uses an individual patient's tumor biology to predict individual risk of squamous cell carcinoma metastasis for patients with one or more risk factors; and DecisionDx DiffDx-Melanoma and myPath Melanoma, a proprietary GEP test to diagnose suspicious pigmented lesions. It offers test services through physicians and their patients. The company was founded in 2007 and is headquartered in Friendswood, Texas.


Insider Transactions at CSTL

Insider Transaction List

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Date Insider Transaction Ownership Type Shares Traded Value / Price
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Last 12 Months Summary

Buy / Acquisition
354K Shares
From 11 Insiders
Exercise of conversion of derivative security 354K shares
Sell / Disposition
382K Shares
From 9 Insiders
Open market or private sale 279K shares
Payment of exercise price or tax liability 102K shares

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