Lauren Mastrocola Praxis Precision Medicines, Inc. (PRAX) insider trading activity

Lauren Mastrocola is Principal Accounting Officer of Praxis Precision Medicines, Inc.. Currently has a direct ownership of 10,441 shares of PRAX, which is worth approximately $2 Million. The most recent transaction as insider was on Nov 20, 2025, when has been sold 13,600 shares (Common Stock) at a price of $192.34 per share, resulting in proceeds of $2,615,824. This information was disclosed in a Form 4 filing with the Securities and Exchange Commission (SEC).

Shares Held (Direct Ownership) 10.4K

0% 3M change

86.05% 12M change

Total Value Held $2 Million

Lauren Mastrocola Transaction History

Date	Transaction	Value	Shares Traded	Shares Held
Nov 20 2025	SELL Open market or private sale	$2,615,824 $192.34 p/Share	13,600 Reduced 56.57%	10,441 Common Stock
Nov 20 2025	BUY Exercise of conversion of derivative security	$886,176 $65.16 p/Share	13,600 Added 36.13%	24,041 Common Stock
Feb 12 2025	SELL Payment of exercise price or tax liability	$3,416 $85.4 p/Share	40 Reduced 0.38%	10,441 Common Stock
Jan 12 2025	SELL Payment of exercise price or tax liability	$24,628 $63.15 p/Share	390 Reduced 3.59%	10,481 Common Stock
Jan 10 2025	BUY Grant, award, or other acquisition	-	5,000 Added 31.5%	10,871 Common Stock
Jan 07 2025	SELL Payment of exercise price or tax liability	$2,713 $77.52 p/Share	35 Reduced 0.59%	5,871 Common Stock
Nov 14 2024	SELL Open market or private sale	$424,274 $81.78 p/Share	5,188 Reduced 48.04%	5,612 Common Stock

Nov 14 2024	BUY Grant, award, or other acquisition	$10,995 $37.4 p/Share	294 Added 4.74%	5,906 Common Stock
Nov 14 2024	BUY Exercise of conversion of derivative security	$249,055 $56.94 p/Share	4,374 Added 28.82%	10,801 Common Stock
Jul 29 2024	BUY Grant, award, or other acquisition	-	4,500 Added 41.18%	6,427 Common Stock
Feb 12 2024	SELL Payment of exercise price or tax liability	$2,143 $44.65 p/Share	48 Reduced 2.43%	1,927 Common Stock
Jan 07 2024	SELL Payment of exercise price or tax liability	$881 $25.19 p/Share	35 Reduced 1.74%	1,975 Common Stock
Feb 12 2023	SELL Payment of exercise price or tax liability	$2,801 $3.94 p/Share	711 Reduced 2.3%	30,160 Common Stock
Jan 07 2023	SELL Payment of exercise price or tax liability	$1,310 $2.52 p/Share	520 Reduced 1.66%	30,871 Common Stock
Jun 16 2022	BUY Open market or private purchase	$5,760 $1.92 p/Share	3,000 Added 8.72%	31,391 Common Stock
May 13 2022	BUY Grant, award, or other acquisition	$22,502 $8.8 p/Share	2,557 Added 8.26%	28,391 Common Stock
Feb 12 2022	SELL Payment of exercise price or tax liability	$7,504 $12.85 p/Share	584 Reduced 2.21%	25,834 Common Stock
Jan 07 2022	BUY Grant, award, or other acquisition	-	6,000 Added 18.51%	26,418 Common Stock
Feb 12 2021	BUY Grant, award, or other acquisition	-	8,200 Added 28.65%	20,418 Common Stock
Nov 02 2020	BUY Exercise of conversion of derivative security	$40,319 $3.3 p/Share	12,218 Added 50.0%	12,218 Common Stock

Lauren Mastrocola

Principal Accounting Officer

Cambridge, MA

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