Marcio Souza Praxis Precision Medicines, Inc. (PRAX) insider trading activity

Marcio Souza is Chief Executive Officer of Praxis Precision Medicines, Inc.. Currently has a direct ownership of 76,890 shares of PRAX, which is worth approximately $14.7 Million. The most recent transaction as insider was on Jan 10, 2026, when has been sold 4,252 shares (Common Stock) at a price of $288.45 per share, resulting in proceeds of $1,226,489. This information was disclosed in a Form 4 filing with the Securities and Exchange Commission (SEC).

Shares Held (Direct Ownership) 76.9K

42.63% 3M change

42.49% 12M change

Total Value Held $14.7 Million

Marcio Souza Transaction History

Date	Transaction	Value	Shares Traded	Shares Held
Jan 10 2026	SELL Payment of exercise price or tax liability	$1,226,489 $288.45 p/Share	4,252 Reduced 5.24%	76,890 Common Stock
Jan 08 2026	BUY Grant, award, or other acquisition	-	27,640 Added 25.41%	81,142 Common Stock
Jan 07 2026	SELL Payment of exercise price or tax liability	$118,515 $292.63 p/Share	405 Reduced 0.75%	53,502 Common Stock
May 14 2025	BUY Grant, award, or other acquisition	$10,975 $31.54 p/Share	348 Added 0.64%	53,907 Common Stock
Feb 12 2025	SELL Payment of exercise price or tax liability	$34,245 $85.4 p/Share	401 Reduced 0.74%	53,559 Common Stock
Jan 10 2025	BUY Grant, award, or other acquisition	-	37,500 Added 41.0%	53,960 Common Stock
Jan 07 2025	SELL Payment of exercise price or tax liability	$33,643 $77.52 p/Share	434 Reduced 2.57%	16,460 Common Stock

May 14 2024	BUY Grant, award, or other acquisition	$21,251 $12.37 p/Share	1,718 Added 9.23%	16,894 Common Stock
Feb 12 2024	SELL Payment of exercise price or tax liability	$12,100 $44.65 p/Share	271 Reduced 1.75%	15,176 Common Stock
Jan 07 2024	SELL Payment of exercise price or tax liability	$10,529 $25.19 p/Share	418 Reduced 2.63%	15,447 Common Stock
May 12 2023	BUY Grant, award, or other acquisition	$10,284 $0.88 p/Share	11,687 Added 4.68%	237,986 Common Stock
Mar 23 2023	BUY Open market or private purchase	$30,100 $0.86 p/Share	35,000 Added 13.39%	226,299 Common Stock
Nov 14 2022	BUY Grant, award, or other acquisition	$3,828 $1.81 p/Share	2,115 Added 1.09%	191,299 Common Stock
Jun 08 2022	BUY Open market or private purchase	$49,950 $1.85 p/Share	27,000 Added 12.49%	189,184 Common Stock
May 13 2022	BUY Grant, award, or other acquisition	$12,250 $8.8 p/Share	1,392 Added 0.85%	162,184 Common Stock
Jan 07 2022	BUY Grant, award, or other acquisition	-	74,000 Added 31.52%	160,792 Common Stock
Aug 18 2021	BUY Open market or private purchase	$150,668 $15.79 p/Share	9,542 Added 9.91%	86,792 Common Stock
Feb 12 2021	BUY Grant, award, or other acquisition	-	52,800 Added 40.6%	77,250 Common Stock
Nov 10 2020	BUY Open market or private purchase	$100,304 $26.08 p/Share	3,846 Added 13.59%	24,450 Common Stock
Oct 20 2020	BUY Conversion of derivative security	-	20,604 Added 50.0%	20,604 Common Stock

Also insider at

AGLE

Aeglea BioTherapeutics, Inc. Healthcare

Director

Marcio Souza

Chief Executive Officer

Austin, TX

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