Institutional shares held 22.6 Million
21.5K calls
0 puts
Total value of holdings $102M
$96K calls
$0 puts
Market Cap $158M
35,096,400 Shares Out.
Institutional ownership 64.29%
# of Institutions 74


Latest Institutional Activity in PYXS

Top Purchases

Q3 2025
Perceptive Advisors LLC Shares Held: 1.18M ($5.31M)
Q3 2025
Stem Point Capital LP Shares Held: 690K ($3.11M)
Q3 2025
Bank Of America Corp Shares Held: 616K ($2.78M)
Q3 2025
Longaeva Partners L.P. Shares Held: 503K ($2.27M)
Q3 2025
Driehaus Capital Management LLC Shares Held: 419K ($1.89M)

Top Sells

Q3 2025
Millennium Management LLC Shares Held: 815K ($3.68M)
Q3 2025
Pier 88 Investment Partners LLC Shares Held: 152K ($684K)
Q3 2025
Goldman Sachs Group Inc Shares Held: 125K ($566K)
Q3 2025
Aqr Capital Management LLC Shares Held: 13.8K ($62.4K)
Q3 2025
Qube Research & Technologies LTD Shares Held: 30.8K ($139K)

About PYXS

Pyxis Oncology, Inc., a preclinical stage biopharmaceutical company, engages in the development of therapies to treat cancers. Its immune-oncology product candidates include PYX-106, an investigational fully human immunoglobulin G1 isotype siglec-15 targeting antibody for the treatment of thyroid cancer, head and neck squamous cell carcinoma, non-small cell lung cancer (NSCLC), and other solid tumors; and PYX-102, an investigational immune-therapeutic for treatment of solid tumors. The company's antibody drug conjugate (ADC) product candidates comprise of PYX-201, an investigational novel ADC to treat NSCLC, breast cancer, and other solid tumors; PYX-202, an investigational novel ADC for treatment of SCLC, soft tissue sarcoma, and other solid tumors; and PYX-203, an investigational ADC for the treatment of acute myeloid leukemia and myeloid dysplastic syndrome. The company was incorporated in 2018 and is headquartered in Cambridge, Massachusetts.


Insider Transactions at PYXS

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Date Insider Transaction Ownership Type Shares Traded Value / Price
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Last 12 Months Summary

Buy / Acquisition
0 Shares
From 0 Insiders
Sell / Disposition
0 Shares
From 0 Insiders

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