The Securities and Exchange Commission has not necessarily reviewed the information in this filing and has not determined if it is accurate and complete.
The reader should not assume that the information is accurate and complete.

UNITED STATES SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549
FORM 13F

FORM 13F INFORMATION TABLE
OMB APPROVAL
OMB Number: 3235-0006
Estimated average burden
hours per response: 23.8
COLUMN 1 COLUMN 2 COLUMN 3 COLUMN 4 COLUMN 5 COLUMN 6 COLUMN 7 COLUMN 8
VALUE SHRS OR SH/ PUT/ INVESTMENT OTHER VOTING AUTHORITY
NAME OF ISSUER TITLE OF CLASS CUSIP FIGI (to the nearest dollar) PRN AMT PRN CALL DISCRETION MANAGER SOLE SHARED NONE
4D MOLECULAR THERAPEUTICS IN COM 35104E100   6,666,789 1,196,910 SH   SOLE   1,196,910 0 0
89BIO INC COM 282559103   16,947,316 2,167,176 SH   SOLE   2,167,176 0 0
ABSCI CORPORATION COM 00091E109   21,623,688 8,253,316 SH   SOLE   8,253,316 0 0
AC IMMUNE SA SHS H00263105   2,792,607 1,034,299 SH   SOLE   1,034,299 0 0
ACHILLES THERAPEUTICS PLC SPONSORED ADS 00449L102   1,833,221 1,608,089 SH   SOLE   1,608,089 0 0
ADAPTIMMUNE THERAPEUTICS PLC SPONDS ADR 00653A107   385,497 715,607 SH   SOLE   715,607 0 0
ADC THERAPEUTICS SA SHS H0036K147   31,176,795 15,666,731 SH   SOLE   15,666,731 0 0
AKERO THERAPEUTICS INC COM 00973Y108   34,363,514 1,235,209 SH   SOLE   1,235,209 0 0
ALLAKOS INC COM 01671P100   3,648,267 3,015,097 SH   SOLE   3,015,097 0 0
ALLOVIR INC COM 019818103   801,347 1,907,969 SH   SOLE   1,907,969 0 0
ALX ONCOLOGY HLDGS INC COM 00166B105   6,161,650 3,689,611 SH   SOLE   3,689,611 0 0
AMICUS THERAPEUTICS INC COM 03152W109   66,457,064 7,054,890 SH   SOLE   7,054,890 0 0
ANNEXON INC COM 03589W102   32,322,304 6,300,644 SH   SOLE   6,300,644 0 0
ARDELYX INC COM 039697107   7,991,633 1,576,259 SH   SOLE   1,576,259 0 0
ASTRIA THERAPEUTICS INC COM 04635X102   3,095,725 346,278 SH   SOLE   346,278 0 0
ATARA BIOTHERAPEUTICS INC COM NEW 046513206   5,879,040 441,701 SH   SOLE   441,701 0 0
BEAM THERAPEUTICS INC COM 07373V105   37,908,462 1,528,567 SH   SOLE   1,528,567 0 0
BIOHAVEN LTD COM G1110E107   33,782,926 904,496 SH   SOLE   904,496 0 0
BIONTECH SE SPONSORED ADS 09075V102   9,511,520 83,471 SH   SOLE   83,471 0 0
BOSTON SCIENTIFIC CORP COM 101137107   27,928,846 312,683 SH   SOLE   312,683 0 0
BOUNDLESS BIO INC COM 10170A100   2,146,592 740,204 SH   SOLE   740,204 0 0
CELLDEX THERAPEUTICS INC NEW COM NEW 15117B202   15,560,634 615,775 SH   SOLE   615,775 0 0
CERIBELL INC COM 15678C102   11,263,985 435,239 SH   SOLE   435,239 0 0
COGENT BIOSCIENCES INC COM 19240Q201   27,727,721 3,554,836 SH   SOLE   3,554,836 0 0
CYTOKINETICS INC COM NEW 23282W605   4,355,810 92,598 SH   SOLE   92,598 0 0
ESTABLISHMENT LABS HLDGS INC COM G31249108   14,749,264 320,149 SH   SOLE   320,149 0 0
FATE THERAPEUTICS INC COM 31189P102   21,240,361 12,872,946 SH   SOLE   12,872,946 0 0
HOOKIPA PHARMA INC COM NEW 43906K209   213,816 106,376 SH   SOLE   106,376 0 0
IDEAYA BIOSCIENCES INC COM 45166A102   15,916,010 619,300 SH   SOLE   619,300 0 0
IGM BIOSCIENCES INC COM 449585108   18,037,520 2,952,131 SH   SOLE   2,952,131 0 0
IMMUNOME INC COM 45257U108   51,273,636 4,828,026 SH   SOLE   4,828,026 0 0
IMMUNOVANT INC COM 45258J102   14,164,080 571,824 SH   SOLE   571,824 0 0
INSULET CORP COM 45784P101   2,495,568 9,559 SH   SOLE   9,559 0 0
INTUITIVE SURGICAL INC COM NEW 46120E602   8,843,568 16,943 SH   SOLE   16,943 0 0
INVIVYD INC COM 00534A102   1,334,730 3,012,254 SH   SOLE   3,012,254 0 0
KEROS THERAPEUTICS INC COM 492327101   8,746,170 552,506 SH   SOLE   552,506 0 0
KRYSTAL BIOTECH INC COM 501147102   117,992,396 753,175 SH   SOLE   753,175 0 0
KYMERA THERAPEUTICS INC COM 501575104   44,270,379 1,100,432 SH   SOLE   1,100,432 0 0
LAVA THERAPEUTICS NV SHS N51517105   1,972,728 2,074,372 SH   SOLE   2,074,372 0 0
LIVANOVA PLC SHS G5509L101   48,326,291 1,043,539 SH   SOLE   1,043,539 0 0
NEUROGENE INC COM 64135M105   30,169,782 1,319,763 SH   SOLE   1,319,763 0 0
NURIX THERAPEUTICS INC COM 67080M103   78,989,093 4,192,627 SH   SOLE   4,192,627 0 0
NUVATION BIO INC COM CL A 67080N101   8,062,484 3,031,009 SH   SOLE   3,031,009 0 0
ORUKA THERAPEUTICS INC COM 687604108   7,983,406 411,728 SH   SOLE   411,728 0 0
PENUMBRA INC COM 70975L107   6,113,448 25,743 SH   SOLE   25,743 0 0
PLIANT THERAPEUTICS INC COM 729139105   38,133,445 2,895,478 SH   SOLE   2,895,478 0 0
PRIME MEDICINE INC COM 74168J101   6,057,102 2,074,350 SH   SOLE   2,074,350 0 0
RAPT THERAPEUTICS INC COM 75382E109   10,231,001 6,475,317 SH   SOLE   6,475,317 0 0
REGENXBIO INC COM 75901B107   37,063,649 4,794,780 SH   SOLE   4,794,780 0 0
REPARE THERAPEUTICS INC COM 760273102   2,510,077 1,916,089 SH   SOLE   1,916,089 0 0
REPLIMUNE GROUP INC COM 76029N106   59,405,932 4,905,527 SH   SOLE   4,905,527 0 0
SCHOLAR ROCK HLDG CORP COM 80706P103   196,645,857 4,549,881 SH   SOLE   4,549,881 0 0
SHATTUCK LABS INC COM 82024L103   6,703,066 5,539,724 SH   SOLE   5,539,724 0 0
SILENCE THERAPEUTICS PLC ADS 82686Q101   16,507,301 2,399,317 SH   SOLE   2,399,317 0 0
SOLID BIOSCIENCES INC COM NEW 83422E204   2,460,984 615,246 SH   SOLE   615,246 0 0
STEREOTAXIS INC COM NEW 85916J409   4,102,780 1,799,465 SH   SOLE   1,799,465 0 0
STOKE THERAPEUTICS INC COM 86150R107   50,667,728 4,593,629 SH   SOLE   4,593,629 0 0
STRYKER CORPORATION COM 863667101   11,044,894 30,676 SH   SOLE   30,676 0 0
VENTYX BIOSCIENCES INC COM 92332V107   271,950 124,178 SH   SOLE   124,178 0 0
VERVE THERAPEUTICS INC COM 92539P101   7,434,445 1,318,164 SH   SOLE   1,318,164 0 0
XERIS BIOPHARMA HOLDINGS INC COM 98422E103   1,529,226 451,099 SH   SOLE   451,099 0 0
ZYMEWORKS INC COM 98985Y108   70,864,378 4,840,463 SH   SOLE   4,840,463 0 0