Rhythm Pharmaceuticals, Inc. RYTM
We take great care to ensure that the data presented and summarized in this overview for RHYTHM PHARMACEUTICALS, INC. is accurate and up-to-date, based on a comprehensive analysis of 13F filing forms for institutional ownership and form 4 filings for insider transactions. Please note that this data may differ from other sources and should not be relied upon as the sole basis for investment decisions.
Top Institutions Holding RYTM
View all-
Perceptive Advisors LLC New York, NY419MShares$41.7 Billion94.44% of portfolio
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Black Rock Inc. New York, NY6.74MShares$670 Million0.01% of portfolio
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Ra Capital Management, L.P. Boston, MA5.68MShares$565 Million9.85% of portfolio
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Baker Bros. Advisors LP New York, NY5.6MShares$557 Million4.61% of portfolio
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Vanguard Group Inc Valley Forge, PA5MShares$497 Million0.01% of portfolio
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Primecap Management CO Pasadena, CA4.26MShares$424 Million0.34% of portfolio
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Nea Management Company, LLC Timonium, MD2.91MShares$289 Million18.37% of portfolio
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State Street Corp Boston, MA2.03MShares$202 Million0.01% of portfolio
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Goldman Sachs Group Inc New York, NY1.89MShares$188 Million0.02% of portfolio
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Federated Hermes, Inc. Pittsburgh, PA1.73MShares$172 Million0.33% of portfolio
Latest Institutional Activity in RYTM
Top Purchases
Top Sells
About RYTM
Rhythm Pharmaceuticals, Inc., a commercial-stage biopharmaceutical company, focuses on the development and commercialization of therapeutics for the treatment of rare genetic diseases of obesity. The company's lead product candidate is IMCIVREE, a potent melanocortin-4 receptor for the treatment of pro-opiomelanocortin (POMC), proprotein convertase subtilisin/kexin type 1, leptin receptor (LEPR) deficiency obesity, and Bardet-Biedl and Alström syndrome. It is also developing setmelanotide, which is in Phase II clinical trials for treating POMC or LEPR heterozygous deficiency obesities, steroid receptor coactivator 1 deficiency obesity, SH2B1 deficiency obesity, MC4 receptor deficiency obesity, Smith-Magenis syndrome obesity, POMC epigenetic disorders, and other MC4R disorders. Rhythm Pharmaceuticals, Inc. has a collaborative research agreement with the Clinical Registry Investigating Bardet-Biedl Syndrome. The company was formerly known as Rhythm Metabolic, Inc. and changed its name to Rhythm Pharmaceuticals, Inc. in October 2015. Rhythm Pharmaceuticals, Inc. was founded in 2008 and is headquartered in Boston, Massachusetts.
Insider Transactions at RYTM
Insider Transaction List
View all| Date | Insider | Transaction | Ownership Type | Shares Traded | Value / Price |
|---|---|---|---|---|---|
|
Nov 20
2025
|
Pamela J. Cramer Chief Human Resources Officer |
SELL
Open market or private sale
|
Direct |
3,350
-13.86%
|
$351,750
$105.0 P/Share
|
|
Nov 20
2025
|
Pamela J. Cramer Chief Human Resources Officer |
BUY
Exercise of conversion of derivative security
|
Direct |
3,350
+12.18%
|
$90,450
$27.35 P/Share
|
|
Nov 10
2025
|
Pamela J. Cramer Chief Human Resources Officer |
SELL
Open market or private sale
|
Direct |
3,515
-14.45%
|
$351,500
$100.0 P/Share
|
|
Nov 10
2025
|
Pamela J. Cramer Chief Human Resources Officer |
BUY
Exercise of conversion of derivative security
|
Direct |
3,515
+12.62%
|
$21,090
$6.8 P/Share
|
|
Nov 07
2025
|
Pamela J. Cramer Chief Human Resources Officer |
SELL
Open market or private sale
|
Direct |
19,351
-48.18%
|
$1,896,398
$98.82 P/Share
|
|
Nov 07
2025
|
Pamela J. Cramer Chief Human Resources Officer |
BUY
Exercise of conversion of derivative security
|
Direct |
19,351
+21.86%
|
$232,212
$12.91 P/Share
|
|
Oct 30
2025
|
Joseph Shulman Chief Technical Officer |
SELL
Open market or private sale
|
Direct |
9,748
-53.39%
|
$1,121,020
$115.24 P/Share
|
|
Oct 30
2025
|
Joseph Shulman Chief Technical Officer |
BUY
Exercise of conversion of derivative security
|
Direct |
9,748
+34.81%
|
$292,440
$30.66 P/Share
|
|
Oct 28
2025
|
Joseph Shulman Chief Technical Officer |
SELL
Open market or private sale
|
Direct |
2,815
-24.86%
|
$323,725
$115.01 P/Share
|
|
Oct 28
2025
|
Joseph Shulman Chief Technical Officer |
BUY
Exercise of conversion of derivative security
|
Direct |
2,815
+11.24%
|
$81,635
$29.01 P/Share
|
|
Oct 16
2025
|
Joseph Shulman Chief Technical Officer |
SELL
Open market or private sale
|
Direct |
14,437
-27.17%
|
$1,602,507
$111.94 P/Share
|
|
Oct 16
2025
|
Joseph Shulman Chief Technical Officer |
BUY
Exercise of conversion of derivative security
|
Direct |
14,437
+25.73%
|
$418,673
$29.01 P/Share
|
|
Sep 02
2025
|
Joseph Shulman Chief Technical Officer |
SELL
Open market or private sale
|
Direct |
16,781
-66.35%
|
$1,762,005
$105.3 P/Share
|
|
Sep 02
2025
|
Joseph Shulman Chief Technical Officer |
BUY
Exercise of conversion of derivative security
|
Direct |
16,781
+26.62%
|
$486,649
$29.01 P/Share
|
|
Aug 21
2025
|
Joseph Shulman Chief Technical Officer |
SELL
Open market or private sale
|
Direct |
4,188
-32.98%
|
$418,800
$100.07 P/Share
|
|
Aug 21
2025
|
Joseph Shulman Chief Technical Officer |
BUY
Exercise of conversion of derivative security
|
Direct |
4,188
+24.8%
|
$113,076
$27.35 P/Share
|
|
Aug 13
2025
|
Hunter C Smith Chief Financial Officer |
SELL
Open market or private sale
|
Direct |
3,477
-2.89%
|
$333,792
$96.0 P/Share
|
|
Aug 13
2025
|
Hunter C Smith Chief Financial Officer |
BUY
Exercise of conversion of derivative security
|
Direct |
3,477
+2.81%
|
$20,862
$6.88 P/Share
|
|
Aug 12
2025
|
Christopher Paul German Corporate Controller & CAO |
SELL
Open market or private sale
|
Direct |
1,500
-61.93%
|
$142,500
$95.0 P/Share
|
|
Aug 12
2025
|
Christopher Paul German Corporate Controller & CAO |
BUY
Exercise of conversion of derivative security
|
Direct |
1,500
+30.12%
|
$49,500
$33.6 P/Share
|
Last 12 Months Summary
| Exercise of conversion of derivative security | 586K shares |
|---|
| Open market or private sale | 491K shares |
|---|