Javier B. Szwarcberg Spruce Biosciences, Inc. (SPRB) insider trading activity

Javier B. Szwarcberg is CHIEF EXECUTIVE OFFICER of SPRUCE BIOSCIENCES, INC.. Currently has a direct ownership of 19,004 shares of SPRB, which is worth approximately $2.02 Million. The most recent transaction as insider was on Dec 31, 2025, when has been sold 4,690 shares (Common Stock) at a price of $4.53 per share, resulting in proceeds of $21,245. This information was disclosed in a Form 4 filing with the Securities and Exchange Commission (SEC).

Shares Held (Direct Ownership) 19K

95.93% 3M change

95.93% 12M change

Total Value Held $2.02 Million

Javier B. Szwarcberg Transaction History

Date	Transaction	Value	Shares Traded	Shares Held
Dec 31 2025	BUY Grant, award, or other acquisition	$21,245 $4.53 p/Share	4,690 Added 19.79%	19,004 Common Stock
Dec 15 2025	SELL Payment of exercise price or tax liability	$109,711 $80.67 p/Share	1,360 Reduced 8.68%	14,314 Common Stock
Dec 15 2025	BUY Exercise of conversion of derivative security	-	2,676 Added 15.21%	14,922 Common Stock
Dec 11 2025	SELL Payment of exercise price or tax liability	$193,971 $88.41 p/Share	2,194 Reduced 14.44%	12,998 Common Stock
Dec 11 2025	BUY Exercise of conversion of derivative security	-	4,950 Added 24.58%	15,192 Common Stock
Dec 10 2025	SELL Payment of exercise price or tax liability	$36,666 $85.67 p/Share	428 Reduced 4.01%	10,242 Common Stock
Dec 10 2025	BUY Exercise of conversion of derivative security	-	1,196 Added 10.08%	10,670 Common Stock

Oct 20 2025	SELL Payment of exercise price or tax liability	$228,018 $148.16 p/Share	1,539 Reduced 13.97%	9,474 Common Stock
Oct 20 2025	BUY Exercise of conversion of derivative security	-	4,784 Added 30.28%	11,013 Common Stock
Dec 16 2024	SELL Payment of exercise price or tax liability	$27,927 $0.39 p/Share	71,610 Reduced 13.29%	467,191 Common Stock
Dec 16 2024	BUY Exercise of conversion of derivative security	-	200,700 Added 28.37%	506,796 Common Stock
Dec 10 2024	SELL Payment of exercise price or tax liability	$69,130 $0.54 p/Share	128,020 Reduced 27.46%	338,101 Common Stock
Dec 10 2024	BUY Exercise of conversion of derivative security	-	358,800 Added 43.5%	466,121 Common Stock
Dec 15 2023	SELL Payment of exercise price or tax liability	$63,717 $1.66 p/Share	38,384 Reduced 26.34%	107,321 Common Stock
Dec 15 2023	BUY Exercise of conversion of derivative security	-	111,000 Added 43.24%	145,705 Common Stock
Jun 30 2023	BUY Grant, award, or other acquisition	$19,600 $0.98 p/Share	20,000 Added 36.56%	34,705 Common Stock
Dec 30 2022	BUY Grant, award, or other acquisition	$13,675 $0.93 p/Share	14,705 Added 50.0%	14,705 Common Stock

JBS

Javier B. Szwarcberg

CHIEF EXECUTIVE OFFICER

Daly City, CA

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